Sentences with phrase «lab mice whose»

To find out, Einstein's George Karagiannis spent nearly three years experimenting with lab mice whose genetic mutations make them spontaneously develop breast cancer, as well as mice given human breast tumors.

Not exact matches

Next, the team tested the GD2 CAR - T cells in mice whose brainstem was implanted with human DIPG tumors, an experimental system that Monje's lab pioneered.

Realizing they might have a potentially effective drug on their hands, Bogyo and his colleagues brought in Sonnenburg, whose lab is adept at using mouse models of C. difficile infection.

Their lab animals of choice were mice and rats, whose physiology is similar to that of humans.

In a paper published Sept. 21 in Cell, Harvard Medical School genetics professor Olivier Pourquié — whose lab discovered the segmentation clock 20 years ago — and colleagues report that they used mouse cells to reconstitute a stable version of this clockwork for the first time in a petri dish, leading to several new discoveries about where the clock is located, what makes it tick and how the vertebral column takes shape.

After eight weeks on a high - fat diet, mice that had been engineered with genes to activate the Hedgehog signaling pathway didn't gain weight (left), but control animals whose Hedgehog pathways were not activated became obese (right)(Credit: Long Lab)

Her lab's most recent work, led by HMS Instructor Cristina Aguayo - Mazzucato, started instead with very old mice, created for another experiment, whose beta cells emitted fluorescent signals.

Another early adopter of the technology is Benoit Bruneau, PhD, whose lab members are using the Lightsheet to capture the origins of congenital heart defects precisely when and where they occur in a mouse embryo.