Using the fruit fly Drosophila, a standard
lab model for studying animal biology, the researchers discovered a cascade of molecular signals that program gene activity to drive the fly from one stage of maturation to the next, like a baby turning into an adult.
The new epidermis, grown from human pluripotent stem cells, offers a cost - effective alternative
lab model for testing drugs and cosmetics, and could also help to develop new therapies for rare and common skin disorders.
Not exact matches
It is no coincidence that the school system in Finland, the darling of the international educational community
for its superior test scores, is built on an experience - based
model, where science and math are taught through doing, and
labs take precedence over textbooks.
And that's clutch
for Dinner
Lab, whose pop - up business
model can lend itself to unforeseen mistakes and problems.
Some restaurant owners and chefs might cringe, but Dinner
Lab's
model shows certain advantages
for getting a side of data with each dish served.
ACC Accounting & Auditing, AFR Africa, AGE Economics of Ageing, AGR Agricultural Economics, ARA Arab World, BAN Banking, BEC Business Economics, CBA Central Banking, CBE Cognitive & Behavioural Economics, CDM Collective Decision - Making, CFN Corporate Finance, CIS Confederation of Independent States, CMP Computational Economics, CNA China, COM Industrial Competition, CSE Economics of Strategic Management, CTA Contract Theory & Applications, CUL Cultural Economics, CWA Central & Western Asia, DCM Discrete Choice
Models, DEM Demographic Economics, DEV Development, DGE Dynamic General Equilibrium, ECM Econometrics, EDU Education, EEC European Economics, EFF Efficiency & Productivity, ENE Energy Economics, ENT Entrepreneurship, ENV Environmental Economics, ETS Econometric Time Series, EUR Microeconomics European Issues, EVO Evolutionary Economics, EXP Experimental Economics, FDG Financial Development & Growth, FIN Finance, FMK Financial Markets,
FOR Forecasting, GEO Economic Geography, GRO Economic Growth, GTH Game Theory, HAP Economics of Happiness, HEA Health Economics, HIS Business, Economic & Financial History, HME Heterodox Microeconomics, HPE History & Philosophy of Economics, HRM Human Capital & Human Resource Management, IAS Insurance Economics, ICT Information & Communication Technologies, IFN International Finance, IND Industrial Organization, INO Innovation, INT International Trade, IPR Intellectual Property Rights, IUE Informal & Underground Economics, KNM Knowledge Management & Knowledge Economy,
LAB Labour Economics, LAM Central & South America, LAW Law & Economics, LMA Labor Markets - Supply, Demand & Wages, LTV Unemployment, Inequality & Poverty, MAC Macroeconomics, MFD Microfinance, MIC Microeconomics, MIG Economics of Human Migration, MKT Marketing, MON Monetary Economics, MST Market Microstructure, NET Network Economics, NEU Neuroeconomics, OPM Open Macroeconomics, ORE Operations Research, PBE Public Economics, PKE Post Keynesian Economics, POL Positive Political Economics, PPM Project, Program & Portfolio Management, PUB Public Finance, REG Regulation, RES Resource Economics, RMG Risk Management, SBM Small Business Management, SEA South East Asia, SOC Social Norms & Social Capital, SOG Sociology of Economics, SPO Sports & Economics, TID Technology & Industrial Dynamics, TRA Transition Economics, TRE Transport Economics, TUR Tourism Economics, UPT Utility
Models & Prospect Theory, URE Urban & Real Estate Economics.
ACC Accounting & Auditing, AFR Africa, AGE Economics of Ageing, AGR Agricultural Economics, ARA Arab World, BAN Banking, BEC Business Economics, CBA Central Banking, CBE Cognitive & Behavioural Economics, CDM Collective Decision - Making, CFN Corporate Finance, CIS Confederation of Independent States, CMP Computational Economics, CNA China, COM Industrial Competition, CSE Economics of Strategic Management, CTA Contract Theory & Applications, CUL Cultural Economics, CWA Central & Western Asia, DCM Discrete Choice
Models, DEM Demographic Economics, DEV Development, DGE Dynamic General Equilibrium, ECM Econometrics, EDU Education, EEC European Economics, EFF Efficiency & Productivity, ENE Energy Economics, ENT Entrepreneurship, ENV Environmental Economics, ETS Econometric Time Series, EUR Microeconomic European Issues, EVO Evolutionary Economics, EXP Experimental Economics, FDG Financial Development & Growth, FIN Finance, FMK Financial Markets,
FOR Forecasting, GEO Economic Geography, GRO Economic Growth, GTH Game Theory, HAP Economics of Happiness, HEA Health Economics, HIS Business, Economic & Financial History, HME Heterodox Microeconomics, HPE History & Philosophy of Economics, HRM Human Capital & Human Resource Management, IAS Insurance Economics, ICT Information & Communication Technologies, IFN International Finance, IND Industrial Organization, INO Innovation, INT International Trade, IPR Intellectual Property Rights, IUE Informal & Underground Economics, KNM Knowledge Management & Knowledge Economy,
LAB Labour Economics, LAM Central & South America, LAW Law & Economics, LMA Labor Markets - Supply, Demand & Wages, LTV Unemployment, Inequality & Poverty, MAC Macroeconomics, MFD Microfinance, MIC Microeconomics, MIG Economics of Human Migration, MKT Marketing, MON Monetary Economics, MST Market Microstructure, NET Network Economics, NEU Neuroeconomics, OPM Open Macroeconomics, PBE Public Economics, PKE Post Keynesian Economics, POL Positive Political Economics, PPM Project, Program & Portfolio Management, PUB Public Finance, REG Regulation, RES Resource Economics, RMG Risk Management, SBM Small Business Management, SEA South East Asia, SOC Social Norms & Social Capital, SOG Sociology of Economics, SPO Sports & Economics, TID Technology & Industrial Dynamics, TRA Transition Economics, TRE Transport Economics, TUR Tourism Economics, UPT Utility
Models & Prospect Theory, URE Urban & Real Estate Economics.
A new business
model, however, is now emerging
for digital art that could alter this perspective.CryptoPunks by Larva
Labs is one known example.
Other indications of evolution are too numerous to actually list in full, but a few might be the clear genetic distinction between Neanderthals and modern man; the overlapping features of hominid and pre-hominid fossil forms; the progressive order of the fossil record (that is, first fish, then amphibians, then reptiles, then mammals, then birds; contradicting the Genesis order and all flood
models); the phylogenetic relationships between extant and extinct species (including distributions of parasitic genetic elements like Endogenous Retroviruses); the real time observations of speciation in the
lab and in the wild; the real time observations of novel functionality in the
lab and wild (both genetic, Lenski's E. coli, and organsimal, the Pod Mrcaru lizards); the observation of convergent evolution defeating arguments of common component creationism (new world v. old world vultures
for instance); and... well... I guess you get the picture.
The Mettler - Toledo stand will feature
models of production lines
for dry, wet, and packaged products, as well as
lab and industrial weighing applications.
Dressed in his blue Knicks practice shorts, he stepped out of the car and slowly walked to the building, where six people were waiting
for him: Laura Tate, a 28 - year - old aspiring
model from Los Angeles who had conducted a 15 - month affair with Johnson; Tate's father, Dennis; her lawyer; two
lab workers; and a three - month - old girl named Taylor Tate Johnson, who was resting quietly in Laura's lap, oblivious to the awkward situation around her.
Daily Fantasy players looking
for additional information and advice should make sure to check out Fantasy
Labs for access to Pro
Models, Lineup Optimizer and other unique data
for your Week 14 lineup.
There are plenty of opportunities to look
for some potentially exploitable prop bets by leveraging our NHL
Models and Trends tool as well as the Bet
Labs database.
Wednesday's opening night features only three games, but there are still plenty of opportunities to look
for some potentially exploitable prop bets by leveraging our NHL
Models and Trends tool as well as the Bet
Labs database.
That means lots of opportunities to look
for some potentially exploitable prop bets by leveraging our NHL
Models and Trends tool as well as the Bet
Labs database.
Sunday features only three games, but there are still plenty of opportunities to look
for some potentially exploitable prop bets by leveraging our NHL
Models and Trends tool as well as the Bet
Labs database.
I will now use my nURS
model described in step 4 to generate an election forecast
for a variety of CON -
LAB leads shown in the blue and green labels in table P0.
«It's impressive, considering that current state - of - the - art numerical weather
models, such as NOA's Global Forecast System, or the European Centre
for Medium - Range Weather Forecasts» operational
model, are only skillful up to one to two weeks in advance,» says paper co-author Cory Baggett, a postdoctoral researcher in the Barnes and Maloney
labs.
«I came to Berkeley
Lab 21 years ago to work on supernova radiative - transfer
modeling and now
for the first time we've used these theoretical
models to prove that we can do cosmology better,» says Nugent.
Strategies that boost the cell's quality control programs, rather than disarm specific pathologic proteins, have looked promising in
lab animals that serve as
models for human neurodegenerative disorders including Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.
Chalfie's
lab did not own a fluorescence microscope and needed to monitor the results; he solved the problem in part by asking microscope salesmen to bring in demo
models, which his
lab hastily used
for real experiments.
«The previous cellular
models were great,» says John Hogenesch, Professor of Pharmacology at the University of Pennsylvania Perelman School of Medicine, «but they needed high end imaging equipment that is out of reach
for most
labs and early stage startups.»
However, existing
model systems
for observing this process in the
lab do not capture this feedback dynamic.
He put together an independent research proposal that was based on research he was already working on in his PI's
lab: the development of computer
models for gamma - ray bursts.
But in the effort to do good, community
lab leaders may have ignored the fact that they're also running businesses, and the current business
models, which rely on classes and membership dues
for revenue, aren't sustainable.
In a new study, Murphy, a molecular biologist at Princeton University, showed that long - lived bodily, or somatic, cells in Caenorhabditis elegans, a one - millimeter nematode commonly used as a
model for aging studies in
labs, activate genetic pathways completely separate from those found in long - lived egg, or oocyte, cells.
When looking
for model organisms, Edsinger explains, it's a real boon to be able to keep many in the
lab at once.
Rossetto has been leading a collaborative effort to create a better experimental setup
for generating
model tsunami waves in the
lab, something she had been told was impossible due to tsunamis» extremely long wavelengths.
Franco is also collaborating with a researcher who came to his
lab seeking help in refining his mouse
models for diabetes.
Tissue engineers have been unable to grow epidermis with the functional barrier needed
for drug testing, and have been further limited in producing an in vitro (
lab)
model for large - scale drug screening by the number of cells that can be grown from a single skin biopsy sample.
«We have found an implementation of the system that allows us to go in the
lab and actually test the predictions of the Dicke
model, and some extensions of it as well, in a system that is not nearly as complicated as people always thought it has to be
for the Dicke physics,» Engels said.
To better determine the role of specific chemoattractants in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow in Luster's
lab, used multiphoton intravital microscopy — an imaging technology pioneered
for studies of immune cell movements in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow in real time the development of IC - induced arthritis in a mouse
model of rheumatoid arthritis.
To examine the role
for endocannabinoids generated in peripheral organs in controlling the overeating of western diet, DiPatrizio and coauthor Donovan A. Argueta, a bioengineering Ph.D. student in his
lab, used a mouse
model of western diet - induced obesity (chronic exposure to high levels of sugars and fats).
Now Lawrence Berkeley National Laboratory (Berkeley
Lab) researchers have extended cryo - EM's impact further by developing a new computational algorithm that was instrumental in constructing a 3 - D atomic - scale
model of bacteriophage P22
for the first time.
Sometimes, a girl can tire of
modelling freebie biotech T - shirts and yearn
for a more stylish look, even in a
lab.
Funding from Future Energy Source Ltd. has allowed Dr Khan and his team to set up
labs in Poole, which include a scale
model of the solar thermal system — an invaluable tool
for testing.
Enormous projects such as ENCODE (
for humans and mice) or modENCODE (
for other
lab model systems, such as the fly Drosophila or the worm C. elegans) have been devoted to collecting these data in order to analyse and interpret them in the framework of genomic data and to form hypotheses about functions and relations.
A fruit fly
model of Duchenne muscular dystrophy allowed Ruohola - Baker's
lab to rapidly score small molecule therapy candidates
for raising the level of sphingosine 1 - phosphate.
Because the amount of fibrosis in the liver is associated with a greater risk of death from NASH, Xiaobo Wang, PhD, associate research scientist in the Department of Medicine at CUMC working in the
lab of Ira Tabas, MD, PhD, looked
for ways to stop fibrosis in a mouse
model of NASH.
Mitchell's prior analysis examined
lab studies that used an Alzheimer's
lab mouse
model that did not allow
for the study of p - tau.
The only reason
for her to be in the
lab during her Ph.D. was to validate the
models she developed.
A friend in another
lab was studying seed beetles, and Tatar realized that the insects, easy to raise and manipulate, would make a good
model for investigating his questions about aging.
For example, in colorectal cancer
lab models, where a mutation in the beta - catenin gene drives MYC to cancerous levels, eliminating PVT1 from these cells made the tumors nearly disappear.
Her
lab is now developing a
model system
for Parkinson's disease that includes brain, liver, and gastrointestinal tissue, which she plans to use to investigate the hypothesis that bacteria found in the gut can influence the development of Parkinson's disease.
For postdocs ready to establish their own lab, the report proposes an idea that we at Next Wave have advocated for years: The creation of larger, more numerous, and more standardized training awards, modeled on some of NIH's «K - 22» awards and — more closely — on the Burroughs Wellcome Fund Career Awar
For postdocs ready to establish their own
lab, the report proposes an idea that we at Next Wave have advocated
for years: The creation of larger, more numerous, and more standardized training awards, modeled on some of NIH's «K - 22» awards and — more closely — on the Burroughs Wellcome Fund Career Awar
for years: The creation of larger, more numerous, and more standardized training awards,
modeled on some of NIH's «K - 22» awards and — more closely — on the Burroughs Wellcome Fund Career Awards.
By creating MARRVEL (
Model organism Aggregated Resources
for Rare Variant ExpLoration) they are now able to help not only their own
lab but also researchers everywhere search databases all at once and in a matter of minutes.
Working with Liangxue Lai, the Li
lab has generated transgenic — not «knock - in» — pigs that are
models for HD.
Ongoing studies from the Discher
lab are focused on finding that sweet spot with additional tumor
models, as well as on how to engineer macrophages
for longer - lasting effect.
With TeraGrid, the Cornell
lab plans to marry such
models to scenarios
for climate change from the Intergovernmental Panel on Climate Change, in hopes of predicting migratory changes — and perhaps extinctions —
for hundreds of species.
Researchers with the Urban Education
Lab and the UChicago Crime
Lab are evaluating the effects of Match's tutoring
model and BAM mentoring
for CPS students.