Like many influenza virologists, John Steel of Emory University in Atlanta often uses a feeble
lab strain of influenza in his studies of how seasonal flu spreads.
The big community of researchers regularly studying C. elegans had missed discovering the selfish role for a simple reason: The main
lab strain of nematodes carries the selfish element, explains study coauthor Eyal Ben - David.
Pletcher's group exposed two
lab strains of fruit flies on caloric restriction to smells created by live yeast, an important constituent of the fly's diet.
Not exact matches
The company currently uses a
lab test that takes a minimum
of eight hours, and sometimes up to a day or two, to get a readout
of what phage or phages will work best against a particular
strain of bacteria.
LAB with improved functionality
of colonic
strains has been achieved in presence
of prebiotics such as non-digestible components viz., glucan, arabinoxylan, oligosachharides, resistant starch in cereals; and glucose, fructose, hemicelluloses and dietary fibersin fruits and vegetables.
Probiotic
strains of lactic acid bacteria (
LAB) can also bring health benefits by releasing bioactive peptides.
Stability
of Antiradical Activity
of Protein Extracts and Hydrolysates from Dry - Cured Pork Loins with Probiotic
Strains of LAB
The microfluidic technology, developed in the
lab of professor Mark Hayes in the Department
of Chemistry and Biochemistry at Arizona State University, uses microscale electric field gradients, acting on extremely small samples, to tell the difference between the two
strains (antibiotic - resistant and antibiotic - susceptible)
of Staphylococcus epidermidis.
Strains of the
lab workhorse roundworm C. elegans that lived longer added more time being frail and had the same portion
of their lives being healthy as normal worms.
FOLLOWING an astonishing blunder that may have allowed a lethal pandemic flu
strain to escape from the
lab, researchers are calling for a higher level
of security to be imposed on work with flu viruses.
The intact virus is pretty redundant as a research tool: the genomes
of many
strains have been thoroughly sequenced and key proteins required by the functioning virus can be made in the
lab.
It was kind
of a silly thing — identifying how much iron a particular
strain of yeast needed to grow optimally but it hooked me on science and
lab work.
After eradication, the WHO closed smallpox research
labs across the world and destroyed all stocks
of the virus except for two duplicate sets
of representative
strains, which were kept for research in two high - security establishments.
In
lab tests, the material killed 99.97 percent
of MRSA, the
strain of Staphylococcus aureus that is resistant to methicillin and other antibiotics, and 99.85 percent
of a multidrug - resistant
strain of E. coli.
Prior tests found that high concentrations
of the soccer ball — shaped buckyballs can kill pure
strains of bacteria growing in the
lab.
In the
lab, the team mixed each
strain of K. veneficum with a species
of algae on which it preys, and recorded the three - dimensional motions
of thousands
of cells using a high - speed holographic microscopy technique they described in 20071.
Now, an international team
of scientists led by Stewart Cole's
lab at EPFL's Global Health Institute have isolated, sequenced and analyzed the genomes
of 154
strains of M. leprae from around the world.
Columbia University microbiologist Vincent Racaniello, who helped develop the first artificial virus in the 1980s, cites the stir created four years ago when nearly 5,000
labs seeking accreditation were mistakenly shipped vials
of the 1957 pandemic flu
strain as part
of their test kits.
As a graduate student in the
lab of microbiologist John Boothroyd
of Stanford University School
of Medicine, Pernas questioned two existing assumptions: that all three main
strains of Toxoplasma interact with mitochondria in the same way, and that the key protein underpinning this relationship had already been found.
Conlon's team is now sequencing P. aeruginosa
strains to see how gene sequences vary between
strains and how this variance affects the ability
of these
strains to produce the aforementioned factors Conlon's
lab has described.
So, researchers at CDC and collaborators used a
lab technique called reverse genetics to make combinations
of H3N2, a seasonal human flu
strain, and the 1997
strain of H5N1.
Then the researchers pitted the bugs against a batch
of susceptible
strains, dumping both onto
lab dishes to see which would reproduce more effectively.
Department
of Energy national
lab researchers found
strain dramatically influences low - temperature oxygen electrocatalysis on perovskite oxides, enhancing bifunctional activity essential for fuel cells and metal — air batteries.
In
lab tests, bacterial
strains of the genera Bacillus, Lactococcus, Pantoea and Burkholderia effectively inhibited the growth
of Pseudomonas bacteria isolated from infected acacia leaves.
Gilmore's
lab sequenced the toxin producing E. faecium
strain as part
of a much wider search for the origins
of enterococcal antibiotic resistance and disease - causing ability.
Lab tests found the exact same
strain of GBS that had infected the baby in the placenta pills.
Investigators found four other incidents in the past decade when deadly pathogens were mishandled, including an event in March when a sample
of the avian flu
strain H5N1 was contaminated with a more lethal
strain and accidentally shipped to a USDA
lab without proper protections.
Researchers at the U.S. Department
of Energy's Lawrence Berkeley National Laboratory (Berkeley
Lab) have engineered a
strain of bacteria that enables a «one - pot» method for producing advanced biofuels from a slurry
of pre-treated plant material.
Proponents
of PPP experiments argue that by studying the properties
of transmissible, virulent flu in the
lab, we can better prepare for
strains that become pandemic naturally — for example, by developing «prepandemic» vaccines.
Prather's
lab has previously engineered E. coli to produce glucaric acid by adding three genes — one each from yeast, mice, and a
strain of bacteria called Pseudomonas syringae.
By isolating five bacterial
strains of endophytes found inside S. halepense rhizomes (subterranean stems used for storage and vegetative reproduction) and growing them in the
lab in different mixtures
of substrates, the authors determined that these microbes were able to fix and mobilize nitrogen, phosphorus, and iron.
The researchers studied growth rates and lag times in both
lab strains and wild yeast by varying the amount
of its prime carbon food source, glucose.
«It's a nasty virus if you're a mouse» but doesn't sicken humans, Steel says
of this 80 - year - old
lab strain, known as PR8.
Roundy begins the tests in Weaver's
lab by mixing a specific
strain of Zika with human blood donated by a local hospital.
The exciting thing is that RNase E is found in many pathogenic bacteria as well as the harmless
strain of E. coli we study in the
lab.»
Although Jackson
Lab probably stocks some 200
strains of mice with disordered personalities, the world still does not have enough — or good enough — crazy mice.
His
lab is looking to see if other materials can show the same behavior and if mechanical
strain can affect the superconducting properties
of the material (these experiments were not carried out at temperatures where BaFe2As2 is a superconductor).
Today, the company announced that sequencing at its
lab in Darmstadt, Germany, in collaboration with the nearby University
of Münster, «strongly suggests that the bacterium... is a new hybrid type
of pathogenic E. coli
strains.»
That very likely means that the virus will transmit between humans as well, Fouchier told ScienceInsider last month, adding that the
lab strain is «probably one
of the most dangerous viruses you can make.»
One panelist was David Furlow, a University
of California at Davis endocrinologist with extensive experience in rat -
strain variations and how they can affect outcomes in the
lab.
The
lab identified the E. coli
strain as a variant
of ST405, one
of the main disease - causing
strains of the bacteria.
His
lab grows row upon row
of corn in upstate New York, crossbreeding one reference
strain — the widely grown B73 — with 25 different varieties.
In
lab dishes with the bacterium and the fungus, P. putida grew six times as dense as did a mutant
strain of the bacterium that couldn't swim.
His
lab has created a
strain of flies in which broken chromosomes are common due to the expression
of a DNA - cutting enzyme.
Last December, Peter Stäheli and his team at the University
of Freiburg, Germany, reported that most
of the human isolates found so far were most closely related to the
strains used in the
labs that had found them — suggesting the findings had been artifacts, caused by contamination.
The flu incident occurred in March when a sample
of a relatively benign avian flu was accidentally contaminated with a deadly influenza
strain at a CDC
lab before being sent out.
Researchers Herman Dierick and Ralph Greenspan
of The Neurosciences Institute in San Diego, California, set out to see if they could breed high levels
of belligerence back into
lab strains and to learn what genes might be implicated.
These assays were used to study the more than 1000 isolates
of the Ames
strain — the
strain used in the attacks — that the FBI rounded up from 16 U.S.
labs, including USAMRIID, and
labs in Canada, Sweden, and the United Kingdom.
A large - scale study
of two
strains of lab mouse by Viola André, Martin Hrabé de Angelis and co-authors shows that the inclusion
of nesting material and shelters as environmental enrichment does not impair the scientific assessment
of a battery
of 164 physiological parameters in mice.
«So far, no one has looked across a variety
of strains of bacteria, as we have done with Staphylococcus aureus, to find these extrachromosomal phages that have potential to play an important role in disease,» says Bryan Utter a postdoc in the
lab and the first author
of the research published June 25 in PLoS ONE.