Sentences with phrase «laboratory mice at»

Not exact matches

Researchers at the University of Michigan's Mary H Weiser Food Allergy Center have developed a nasal vaccine that protects laboratory mice from allergic reactions upon exposure to peanuts, after just three monthly doses.

Researchers at the University of Michigan's Mary H Weiser Food Allergy Center have developed a nasal vaccine that protects laboratory mice from allergic reactions upon exposure to peanuts, after just...

In 2014, highly publicized work in the laboratories of Villeda and Tony Wyss - Coray, PhD, professor of neurology at Stanford, showed that connecting the circulatory system of a young mouse to that of an old mouse could reverse the declines in learning ability that typically emerge as mice age.

One of the research lines that John, an investigator of the Howard Hughes Medical Institute (HHMI) and a professor at The Jackson Laboratory in Bar Harbor, Maine, currently has going is the development of a wireless sensor so tiny it can be implanted into the eye of a mouse.

The result is a repulsive effect, which was used by Yuanming Liu and colleagues at the Jet Propulsion Laboratory in Pasadena, California, to lift a young mouse weighing 10 grams.

Neuroscientists at Cold Spring Harbor Laboratory (CSHL) have mobilized advanced imaging and computational methods to comprehensively map — «count» — the total populations of specific types of cells throughout the mouse brain.

An additional study, currently available at bioRxiv, led by the researchers from the CRG and Cold Spring Harbour Laboratory, highlights the fact that a substantial part of human and mice genes have maintained an essentially constant expression throughout evolution, in tissues and various organs.

Now, in a new study using laboratory - grown cells and mice, Johns Hopkins scientists report that a method they used to track metabolic pathways heavily favored by cancer cells provides scientific evidence for combining anti-cancer drugs, including one in a nanoparticle format developed at Johns Hopkins, that specifically target those pathways.

Using the supercomputers at Almaden and Lawrence Livermore National Laboratory, the group simulated networks that crudely approximated the brains of mice, rats, cats and humans.

With the move to India, Colleen left the lab bench so that she could coordinate the development of facilities at inStem; this included new laboratory space and an animal facility housing mice, rats, fish, and frogs.

With researchers at the Jackson Laboratory in Bar Harbor, Maine, George and colleagues transplanted mouse skin to 19 mice.

This approach is still at the experimental stage (laboratory mice only).

To gain new insights, Luther Bartelt of the University of North Carolina at Chapel Hill and colleagues developed a new laboratory mouse model of co-infection during malnutrition.

Critics postulated that mouse DNA was floating in the air in the laboratories, or lying in wait in the chemical reagents used to find the virus, or sitting at the bottoms of test tubes used to collect blood specimens.

For the new study, researchers in Diamond's laboratory, led by first author Helen Lazear, PhD, now at the University of North Carolina at Chapel Hill, tested five strains of the Zika virus in the mice: the original strain acquired from Uganda in 1947; three strains that circulated in Senegal in the 1980s; and the French Polynesian strain, which caused infections in 2013 and is nearly identical to the strain causing the current outbreak.

Co-author and renal physiology expert Jurgen Schnermann, M.D., and members of his laboratory at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), also part of NIH, demonstrated the early and significant decrease in this rate in MMA mice.

He was conducting laboratory experiments aimed at finding ways to lessen the effects of cancer therapy on ovaries when he noticed that healthy female mice seemed to be losing eggs at unsustainable rates.

Researchers at the Scripps Institution of Oceanography in San Diego, California, suggest that high levels of carbon monoxide in the seals» blood has a protective effect — echoing laboratory research on rats and mice that has found the gas has anti-inflammatory properties and can lead to better outcomes after organ transplant.

The study, which Shay conducted with colleagues at the University of Florida and University of Nebraska, complements work with mice he leads at his OSU laboratory.

In 2005, Rudolf Jaenisch's laboratory at Whitehead reported preliminary success with this strategy, using mouse cells.

Stix: His laboratory is at the Scripps Research Institute in La Jolla very near San Diego and what he showed is that this process could be blocked in mice, but they actually have to come up with a small molecule that is non-toxic.

The study by neurological scientists at Rush University Medical Center found that feeding cinnamon to laboratory mice determined to have poor learning ability made the mice better learners.

Likewise, male mice with a Rett mutation have much more severe symptoms than the females do, says Zhong - wei Zhang, associate professor at the Jackson Laboratory in Bar Harbor, Maine.

In his current position at The Jackson Laboratory, he has overall responsibility for the ongoing operational development of the PDX resource, which generates, banks, and distributes patient - derived xenograft (PDX) mouse models of human cancers.

Published in Neuron, scientists at Cold Spring Harbor Laboratory (CSHL) report their discovery of a neural circuit in the mouse olfactory bulb that explains how our mammalian cousins (and by extension, we) are able to adjust the gain on intense odors.

«We now have a really good picture of this abnormality in mice, and we suspect it is very similar in humans,» said Fuming Zhang, a research professor in the laboratory of Robert J. Linhardt, the Ann and John H. Broadbent Jr»59 Senior Constellation Professor of Biocatalysis and Metabolic Engineering, and a member of the Center for Biotechnology and Interdisciplinary Studies at Rensselaer.

Because the mouse is so well studied, its sequence will speed the understanding of how our own genes work, says mouse geneticist Barbara Knowles, director of research at the Jackson Laboratory in Bar Harbor, Maine.

In the new study, published today in Science Advances, Charles Limoli, a molecular biologist at the University of California, Irvine, and colleagues took male mice to a particle accelerator at the NASA Space Radiation Laboratory in Upton, New York.

Denis Duboule and his colleagues at the European Molecular Biology Laboratory in Heidelberg, working with mice, showed that genes in the Hox - D cluster, which define the head - to - tail body axis, are activated one after another and at a precise time during development of the embryo.

In the Rutgers study, Zong and lead author Ji - An Pan, a scientist in his laboratory, looked at liver and heart damage in laboratory mice and found that the mice in which the TRIM21 gene was inactivated suffered little heart or liver damage when put through the same laboratory procedures used to produce tissue damage in mice with the gene.

In both mouse and fruit fly embryos, Detlev Arendt, an evolutionary biologist at the European Molecular Biology Laboratory in Heidelberg, Germany, has found that cells involved in forming the brain and nerve cord divide into three columns of cells.

Prusiner, together with Fred Cohen and his colleagues, also at UCSF, and Ruth Gabizon at Hadassah University Hospital in Israel, used human prions to infect a special strain of laboratory mice.

In their research, scientists at Rutgers created animal models that closely resemble the cancerous tumors found in women with ovarian cancer by injecting tumor tissues obtained from gynecological cancer patients treated at the Cancer Institute into laboratory mice.

Researchers at Cold Spring Harbor Laboratory have identified the neurons in the brain that determine if a mouse will learn to cope with stress or become depressed.

Rabbits are more similar to humans than laboratory rats or mice, which explains why Jean - Paul Renard, a developmental biologist at the French Agronomy Research Institute in Jouy - en - Josas, spent the better part of three years figuring out how to clone them.

Joshua Hamilton at the Marine Biological Laboratory in Woods Hole, Massachusetts, and his colleagues gave water containing arsenic at 10 ppb to pregnant and lactating mice, then monitored the development of their pups.

Stem cells obtained in mice also show totipotent characteristics never generated in a laboratory, equivalent to those present in human embryos at the 72 - hour stage of development, when they are composed of just 16 cells.

Even small children might be surprised to discover that their representatives in Washington no longer consider rats, mice, and birds used in laboratory experiments to be animals, or at least animals worthy of protection.

Now, the Laboratory of Malaria Immunology Team at the Immunology Frontier Research Center (IFReC), Osaka University, headed by Professor Cevayir COBAN, have used mouse malaria models to show that robust immune activation and invasion of parasite by - products into the bone marrow during and after malaria infection leads to an adverse balance in bone homeostasis - a process usually tightly controlled - by bone forming osteoblasts and bone resorbing osteoclasts.

«The one thing that I think that is useful is maybe when people write knockout papers they might describe the housing conditions in more detail,» says Chris Paszty, scientific director at the biotech company Amgen, Inc., headquartered in Thousand Oaks, Calif., who as a postdoctoral researcher at Lawrence Berkeley National Laboratory developed a mouse model for the study of sickle cell anemia.

A team in the laboratory of Atsuo Ogura at the National Institute of Infectious Diseases in Shinjuku, Tokyo, cloned 12 mice by removing nuclei from testis cells and inserting them into enucleated egg cells.

The following strains of male mice were purchased from The Jackson Laboratory at 8 weeks of age: IL - 15Rα — KO mice (stock no. 003723; n = 20); B6129SF2 / J background control (101045; n = 16).

In addition, the mutant mice responded better to treatment with chemotherapy», says Lena Claesson - Welsh, professor at the Department of Immunology, Genetics and Pathology, at Uppsala University and Science for Life Laboratory, who led the study.

Kohn, Nakhleh and lead author Kevin Liu, their former postdoctoral researcher and now an assistant professor at Michigan State University, employed Rice's supercomputers and the Nakhleh lab's open - source PhyloNet - HMM software to locate statistically likely connections between the re-sequenced complete genomes, some newly determined and some collected previously in a massive effort to understand the evolutionary origins of the laboratory mouse genome.

In 1969 V. Bocchini and Pietro U. Angeletti at the Laboratory of Cell Biology in Rome devised a method for purifying NGF from mouse salivary glands.

Sangwon Kim, Ph.D., of the Johns Hopkins University School of Medicine's Division of Endocrinology, Diabetes and Metabolism, along with researchers at the University of Pennsylvania, found that laboratory mice that had been exposed to a two - week regimen of nicotine displayed no withdrawal symptoms when given the diabetes drug metformin.

Unless otherwise noted, all mice were obtained from The Jackson Laboratory (Bar Harbor, Maine, USA) at 6 — 8 weeks of age and housed in ventilated Plexiglas cages (one to three animals per cage) within a pathogen - free barrier facility that maintained a 12 - hour light / dark cycle.

In the mid-1990s, Woloschak had worked on samples from 7,000 beagles and 50,000 mice that had been irradiated in experiments at the Argonne Research Laboratory in Illinois between 1969 and 1992.

Xiaowei «George» Xu, MD, PhD, associate professor of Pathology and Laboratory Medicine and Dermatology at the Perelman School of Medicine, University of Pennsylvania, and colleagues published in Nature Communications a method for converting adult cells into epithelial stem cells (EpSCs), the first time anyone has achieved this in either humans or mice.

For example, we showed in collaborative work with Jeffrey I. Gordon's laboratory at Washington University in St. Louis last year that transferring the microbes from an obese person into mice raised in a bubble with no microbes of their own resulted in fatter mice.