Not exact matches
In
laboratory tests on embryonic
mice engineered to not express myomerger in skeletal muscle, the animals
did not develop enough muscle fiber to live.
Although the researchers emphasized that
laboratory results involving cell lines and
mice do not necessarily translate to human treatment, they say their findings show that new mTOR inhibitors combined with chemotherapy could become a new treatment strategy for T - ALL.
Although the act covers animals like dogs and chimpanzees, it
does not cover rodents like
laboratory mice.
Moreover, in separate experiments conducted in the United States, treatment with antimalarials
did not affect survival in
laboratory mice infected with Ebola virus.
Experimental research on drugs, immunology, and the development of malaria is typically
done on related Plasmodium species that infect rodents, including
laboratory - reared
mice.
Likewise, male
mice with a Rett mutation have much more severe symptoms than the females
do, says Zhong - wei Zhang, associate professor at the Jackson
Laboratory in Bar Harbor, Maine.
The research was
done with
laboratory mice that consumed different diets and then faced a variety of tests, such as water maze testing, to monitor changes in their mental and physical function, and associated impacts on various types of bacteria.
Although the research was
done in
laboratory mice, the findings have possible implications for human stem cell transplants.
«
Mouse models don't represent the full diversity of the human response,» said Joel W. Blanchard, a PhD candidate in the Baldwin
laboratory who was co-lead author of the study with Research Associate Kevin T. Eade.
Laboratory mouse models are commonly used to study A-T; however,
mice with A-T
do not experience the more debilitating effects that humans
do.
Interestingly, conventional
laboratory mice previously infected with this virus died, but
did not develop symptoms of Ebola hemorrhagic fever.
Genotyping of 5 - HT3AGFP and 5 - HT3AKO
mice were
done per distributor recommendations (MMRRC and Jackson
Laboratory, respectively).
Our
laboratory has assembled a comprehensive set of tools for
doing this, including
mice with conditional ablation of the Btla gene in different subsets of immune cells.
He is replicating the salamander studies he
did at MDIBL on
mice at nearby Jackson
Laboratory.
The work was
done in a
mouse developed in d'Azzo's
laboratory that lacked the NEU1 gene.
Research
done decades ago when the Zika virus was first identified showed that the virus
does not replicate within run - of - the - mill
laboratory mice.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM,
Doe B, Dolan ME, Edie SM, Fuchs H, Gailus - Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez - Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke - Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International
Mouse Phenotyping Consortium; Jackson
Laboratory; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource Center, MacArthur DG, Tocchini - Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bucan M, Murray SA.
Even in inbred
laboratory mice, the same diet
does not affect every individual identically eg
Every living thing on the planet will naturally work to attain greater resources / mating opportunities, etc... In countless
laboratory experiments, using a variety of species, from
mice to primates, animals who were trained to work for rewards, continued to
do so, even when given free access to another food supply.
In those days, we didn't call them «pocket pets», and if you were interested in learning to care for rabbits,
mice, gerbils, guinea pigs, hamsters and rats, you would need to take a course of «
Laboratory Animal Medicine».
The U.S. federal Animal Welfare Act
does not require
laboratories to publish the numbers of rats,
mice, and birds they use.