Sentences with phrase «laboratory models derived»

Establishing a repository of laboratory models derived from patient tumor samples that will enable researchers to more thoroughly investigate drug resistance

Not exact matches

Currently, Deng's laboratory is conducting additional preclinical studies using the human - derived stem cells from Down syndrome patients and mouse models to determine whether cellular and behavioral abnormalities can be improved with minocycline therapy and other candidate drugs.
In his current position at The Jackson Laboratory, he has overall responsibility for the ongoing operational development of the PDX resource, which generates, banks, and distributes patient - derived xenograft (PDX) mouse models of human cancers.
NCI's efforts to develop new laboratory models of human cancer includes vastly increasing the number of human cancer cell lines (grown as two - dimensional and three - dimensional cultures) and patient - derived tumor xenografts.
Methods: As reported in Geophysical Research Letters, the team led by scientists from PNNL and the National Oceanic and Atmospheric Administration's Atlantic Oceanographic and Meteorological Laboratory used both observations and models to derive their new formula.
The mean high temperature projections for 2050 and 2100 were derived from a suite of 28 climate models (CMIP5 / Oak Ridge National Laboratory) under IPCC emissions scenario RCP8.5, averaged over November 22 - 28 for 2030 - 2049 and 2080 - 2099, respectively.»
«Scientific conclusions derive from an understanding of basic laws supported by laboratory experiments, observations of nature, and mathematical and computer modeling.
These simulations can be used as a numerical laboratory in which we can test the reconstruction methods and assess their potential limitations, by pretending to derive proxy records of the model climate, called «pseudo-proxies».
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