Sentences with phrase «laboratory mouse»

The laboratory mouse is the classic model vertebrate.

The more than $ 30 million effort to sequence Tasha «opened everybody's eyes to just how similar the basic genome structure was for dogs and humans — much more so than for the human and laboratory mouse,» Breen says.

«Influence of Intermittent Fasting and High - Fat Diet on Morphological Changes of the Digestive System and On Changes of Lipid Metabolism in the Laboratory Mouse,» Physiological Research, 45 (2), 145 — 51.

«Effect of Intermittent Feeding with High - Fat Diet on Changes of Glycogen, Protein and Fat Content in Liver and Skeletal Muscle in the Laboratory Mouse,» Physiological Research, 45 (5), 379 - 83 Publisher — Google Scholar

Mouse Genome Database (MGD)-2018: knowledgebase for the laboratory mouse.

Mouse Genome Informatics; international database resource for the laboratory mouse, including integrated genetic, genomic, and biological data.

The project was born in 2011, when Golshani read about a miniaturized microscope developed at Stanford University that was light enough to be worn by a laboratory mouse.

Basic overview of laboratory mouse genetics / Advanced mouse genetics programs: European and international new programs.

CNR Monterotondo Workshop on Cryopreservation and Recovery Techniques in the Laboratory Mouse, November 07 - 10, 2016

The laboratory mouse, small and easy to breed, has long been biologists» favorite model organism for studying mammalian development.

A breed of dwarf mouse that entirely lacks growth hormone is the present winner of the Mprize for longevity, living 60 - 70 % longer than the compeition's standard laboratory mouse species.

Researchers at the MDI Biological Laboratory have been using animal models beyond the well - known laboratory mouse for decades.

The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse.

This species has served as the laboratory mouse of botanical research.

We are currently focusing our efforts on an exceptional resource of laboratory mouse strains with proven Mendelian disorders with unknown genetic etiology, strains stewarded by the Mouse Mutant Resource at The Jackson Laboratory for over 50 years.

Using cell culture and laboratory mouse experiments, the researchers showed that the enzyme, aldose reductase, is essential to a process known as goblet cell metaplasia that is seen in both asthma and COPD.

Our results not only will illuminate how a laboratory mouse behaves but might one day even explain how a professional tennis player hits a forehand.

One of the most important tools at our scientific disposal in understanding mammalian gene function is the laboratory mouse.

In: The Laboratory Mouse, 2nd Edition, edited by Hans J. Hedrich.

In: Laboratory Mouse, Handbook of Experimental Animals Series, Hedrich HJ, Bullock G, Petrusz P (eds.)

In a series of publications today in the British scientific journal Nature, international teams of researchers published a nearly complete sequence of the genetic instructions of «Black 6,» the most common breed of laboratory mouse, and matched its traits with the recently decoded human genome.

CRISPR genome editing has made it easier to create knockout alleles in a variety of species, including the standard laboratory mouse.

Kohn, Nakhleh and lead author Kevin Liu, their former postdoctoral researcher and now an assistant professor at Michigan State University, employed Rice's supercomputers and the Nakhleh lab's open - source PhyloNet - HMM software to locate statistically likely connections between the re-sequenced complete genomes, some newly determined and some collected previously in a massive effort to understand the evolutionary origins of the laboratory mouse genome.

There was no military band or White House reception this time, but researchers celebrated the release of an important mammalian genome 6 May — that of a laboratory mouse called the «black 6.»

Laboratory mouse models are commonly used to study A-T; however, mice with A-T do not experience the more debilitating effects that humans do.

Next, the scientists cloned the gene from the prairie vole's vasopressin receptor and implanted it in an embryo of the less sociable laboratory mouse.

In testing on laboratory mouse models and human MDS / AML samples, the researchers identified a novel substrate of TRAF6 called hnRNPA1, an RNA binding protein.

Using laboratory mouse models of inflammatory and neuropathic pain, they showed that the antibody can target the Nav1.7 channel and reduce the pain sensation in these mice.

A cousin of cabbage and radishes, Arabidopsis is the laboratory mouse of the plant world.

The scientists are able to use tissue not only from laboratory mouse models, but also from human patients.

The Jackson Laboratory mouse population is the largest collection of its kind in the world.

To gain new insights, Luther Bartelt of the University of North Carolina at Chapel Hill and colleagues developed a new laboratory mouse model of co-infection during malnutrition.

This study identifies myomerger as a fundmentally required protein for muscle development using cell culture and laboratory mouse models.

Influence of intermittent fasting and high - fat diet on morphological changes of the digestive system and on changes of lipid metabolism in the laboratory mouse

But, as journalist Steve Connor reports, the reference to editing was intentional: «Scientists have used the genome - editing technology to cure adult laboratory mice of an inherited liver disease by correcting a single «letter» of the genetic alphabet which had been mutated in a vital gene involved in liver metabolism.»

Testing with laboratory mice have shown negative impacts on respiratory, digestive, and reproductive systems, among others.

Researchers at the University of Michigan's Mary H Weiser Food Allergy Center have developed a nasal vaccine that protects laboratory mice from allergic reactions upon exposure to peanuts, after just three monthly doses.

Researchers have developed a vaccine for preventing allergic reactions to peanuts in laboratory mice.

Researchers at the University of Michigan's Mary H Weiser Food Allergy Center have developed a nasal vaccine that protects laboratory mice from allergic reactions upon exposure to peanuts, after just...

A study published in the October, 1999 issue of the Archives of Environmental Health found that laboratory mice exposed to various brands of disposable diapers suffered increased eye, nose, and throat irritation, including bronchoconstriction similar to that of an asthma attack.

In a breakthrough study that could improve how people learn and retain information, the researchers significantly boosted the memory and mental performance of laboratory mice through electrical stimulation.

However, in some studies with laboratory mice, Feinberg had observed that these epigenetic tags varied considerably among the mice even when comparing the same type of tissue in animals that have been living in the exact same conditions.

Laboratory mice that have received rapamycin have reduced the age - dependent decline in spontaneous activity, demonstrated more fitness, improved cognition and cardiovascular health, had less cancer and lived substantially longer than mice fed a normal diet.

Aside from a food intake in laboratory mice that's about 40 percent fewer calories than normal, however, it's been found that another way to activate this pathway is with rapamycin, which appears to have a significant impact even when used late in life.

Although the act covers animals like dogs and chimpanzees, it does not cover rodents like laboratory mice.

(It's relatively easy to cure cancer in laboratory mice — «If you can't cure cancer in a mouse,» a cancer researcher once said to me, «then you should change careers» — but certainly not easy in people.

The scientists then exposed humanized laboratory mice to either brain or skin extracts from two of the CJD patients.

Compared with earlier methods to tweak the genomes of bacteria, plants, laboratory mice and human cells, the Crispr - Cas9 gene - editing method is fast, precise and cheap, an order of magnitude better than the others.

Moreover, in separate experiments conducted in the United States, treatment with antimalarials did not affect survival in laboratory mice infected with Ebola virus.

This approach is still at the experimental stage (laboratory mice only).