The phrase
"laboratory strains" refers to specific types of organisms that have been altered or genetically modified to be used for scientific experiments and research conducted in a laboratory. These organisms are specially bred or engineered to have certain characteristics or traits that make them more useful for specific scientific purposes.
Full definition
A team of international researchers has found that a strain of anthrax - causing bacterium thought to have been viable 80 years after a thwarted World War I espionage attack, was, in reality, a much younger
standard laboratory strain.
But Trudy MacKay, a geneticist at North Carolina State University in Raleigh whose research group published a similar study in PLoS Genetics on 2 August, says that Dierick and Greenspan may have missed many aggression - linked genes because they used inbred
laboratory strains with a limited amount of genetic variation.
Their content is optimized for genetic mapping in the Collaborative Cross and Diveristy Outbred populations; for discriminating haplotypes from
common laboratory strains and substrains; and for evaluating the ancestry of wild - caught mice.
In what was originally a separate line of investigation, David Baker and Taane Clark and colleagues at the London School of Hygiene & Tropical Medicine and the Wellcome Trust Sanger Institute analyzed the whole - genome sequences of two P.
falciparum laboratory strains that they knew were unable to produce gametocytes.
The researchers modified an
ordinary laboratory strain of the ubiquitous human gut microbe Escherichia coli, enabling the bacteria to not only record their interactions with the environment but also time - stamp the events.
For these experiments, mice were treated with 200 µg of mAb intraperitoneally 12 h before infection with a lethal dose of either pandemic H1N1 influenza or either of the two common
influenza laboratory strains PR / 8/34 or FM / 1/47.
Comparative efficacy of four commercially available heartworm preventive products against the
MP3 laboratory strain of Dirofilaria immitis.
Valway then infected mice with the new strain and found 1000 times more bacteria in their lungs after 20 days than in mice infected with a
standard laboratory strain.
These laboratory strains could be passed between mammals more easily than wild strains of the virus.
This could also be the reason why
some laboratory strains seem to have lost the ability to produce darcin: Because laboratory mice are usually group - housed, they have been selected to be less aggressive, and not producing darcin could help reduce tensions.
While
the laboratory strain of Dicty grazes contentedly on bacteria provided for it by its keepers, roughly a third of the wild strains turned out to be primitive farmers.
Roberts» lab introduced the protein, an enzyme with the shorthand name of APOBEC, into
a laboratory strain of the baker's yeast Saccharomyces cerevisiae.
So beyond the «regular» high occurrence of benign and malignant tumors in rats,
the laboratory strains are probably going to have even higher rates of cancer incidence — they're just not as genetically varied as pet rats who've been allowed to explore OKCupid or, more likely, had a descendant who met a special someone from another alley [source: Ducummon].
There are a large number of
laboratory strains available, and their long breeding history means that mice of a single laboratory strain are isogenic.