Sentences with phrase «laboratory used human»

In a series of studies published since 2009, researchers in Wells» laboratory used human pluripotent stem cells (hPSCs) to grow embryonic - stage small intestines with a functioning nervous system, and the antrum and fundus regions of the human stomach.

Gage's lab also models diseases in the laboratory using human stem cells.

Not exact matches

A related area of problems arises in connection with the probable increase of organ transplants, the use of artificial bodily parts, and the probability of growing human embryos in the laboratory.

A panel of nineteen experts appointed by the National Institutes of Health has recommended government funding for conceiving human embryos in the laboratory for the sole purpose of using them as materials for research.

His article is occasioned by the National Institutes of Health proposal to fund producing human embryos in the laboratory solely for the purpose of research (see «The Inhuman Use of Human Beings,» FT, January 1human embryos in the laboratory solely for the purpose of research (see «The Inhuman Use of Human Beings,» FT, January 1Human Beings,» FT, January 1995).

Extensive research using improved epidemiologic methods and modern laboratory techniques documents diverse and compelling advantages for infants, mothers, families, and society from breastfeeding and use of human milk for infant feeding.1 These advantages include health, nutritional, immunologic, developmental, psychologic, social, economic, and environmental benefits.

Researchers at the European Union Reference Laboratory for alternatives to animal testing developed five different tests that use human blood cells to detect contaminants in drugs that cause a potentially dangerous fever response.

While other papers have examined these mutations using expensive and time - consuming experiments on live ferrets and laboratory cell cultures, Deem and Melia Bonomo used the pEpitope method to rapidly calculate how much the egg - passage mutations would decrease vaccine efficacy in humans.

«The stringent application of medical device standards to our laboratory research means that these sensors will be qualified at the highest level for human use and translatable between sports science and medicine.

Dr. Zubair, medical and scientific director of the Cell Therapy Laboratory at Mayo Clinic in Florida, says the experiment will be the first one Mayo Clinic has conducted in space and the first to use these human stem cells, which are found in bone marrow.

With between 80,000 and 150,000 different synthetic chemicals manufactured regularly, it might be too much to expect that a small number of laboratory tests could be used to judge their effect on humans.

A big drawback to long - term use of rapamycin, however, is the increase in insulin resistance, observed in both humans and laboratory animals.

Used in gardens, farms, and parks around the world, the weed killer Roundup contains an ingredient that can suffocate human cells in a laboratory, researchers say

Currently, Deng's laboratory is conducting additional preclinical studies using the human - derived stem cells from Down syndrome patients and mouse models to determine whether cellular and behavioral abnormalities can be improved with minocycline therapy and other candidate drugs.

His laboratory discovered that some of the same RNA that is inside human cells are also present in saliva and can be used to detect diseases — a surprising finding, he said, because enzymes in saliva can degrade RNA, making the mouth «a hostile environment.»

Using the supercomputers at Almaden and Lawrence Livermore National Laboratory, the group simulated networks that crudely approximated the brains of mice, rats, cats and humans.

Building on the newly - published pilot study, the team will conduct experiments using a windtunnel which measures the behaviour of mosquitoes towards odours and electrodes which track the response of individual odour - detecting cells from within the antenna of the mosquito in specially - designed secure laboratories at the School to measure the responses of malaria - infected Anopheles gambiae s.s. females to human odours.

The model has been validated through laboratory experiments on a human - made freak or rogue wave (the so - called «soliton splash») using test tanks.

Most animal studies of the disease are conducted with laboratory mice that have been genetically engineered and bred to model ALS, but for this research, investigators used rats with ALS because they more accurately portray the disease's variable course in humans.

The laboratory process, described in the journal Scientific Reports, entails genetically modifying a line of human embryonic stem cells to become fluorescent upon their differentiation to retinal ganglion cells, and then using that cell line for development of new differentiation methods and characterization of the resulting cells.

In laboratory tests using fruit flies, the researchers discovered that a human genetic mutation that causes Parkinson's amplified visual signals in young flies dramatically.

Research in the laboratory of Rebecca Wingert, the Gallagher Family Associate Professor of Adult Stem Cell Research in the Department of Biological Sciences at the University of Notre Dame, has confirmed the key role of a certain small molecule in the development of kidney structures in zebrafish, a widely used model for human kidneys.

Unique protein markers in hair could be used alongside DNA profiling for human identification, according to a study published September 7, 2016 in the open - access journal PLOS ONE by Glendon Parker from Lawrence Livermore National Laboratory, USA, and colleagues.

Hudson's laboratory used laser light to cool tiny amounts of the reactant atoms and molecules to an extremely low temperature — one one - thousandth of a degree above absolute zero — and then levitate them in a space smaller than the width of a human hair, inside of a vacuum chamber.

The scientists are able to use tissue not only from laboratory mouse models, but also from human patients.

Such ease of use will likely encourage the use of more animal models in the study of human diseases, says Rhonda Wiler, a geneticist at biotech giant Genentech in San Francisco, California, who co-chairs the Roundtable on Science and Welfare in Laboratory Animal Use (which organized the workshouse will likely encourage the use of more animal models in the study of human diseases, says Rhonda Wiler, a geneticist at biotech giant Genentech in San Francisco, California, who co-chairs the Roundtable on Science and Welfare in Laboratory Animal Use (which organized the workshouse of more animal models in the study of human diseases, says Rhonda Wiler, a geneticist at biotech giant Genentech in San Francisco, California, who co-chairs the Roundtable on Science and Welfare in Laboratory Animal Use (which organized the workshoUse (which organized the workshop).

Combining chemotherapy and birinapant significantly improved disease - free survival in laboratory models of human ovarian cancer compared to using either therapy alone.

Prusiner, together with Fred Cohen and his colleagues, also at UCSF, and Ruth Gabizon at Hadassah University Hospital in Israel, used human prions to infect a special strain of laboratory mice.

A team of researchers led by the Department of Energy's Oak Ridge National Laboratory used neutron macromolecular crystallography to investigate the different states of three glaucoma drugs as they interact with the targeted enzyme, human carbonic anhydrase II (hCA II).

By using supercomputers such as Titan, a large multidisciplinary team of scientists led by Peter Thornton of the US Department of Energy's (DOE's) Oak Ridge National Laboratory (ORNL) had the power required to integrate massive codes that combine physical and biological processes in Earth system with feedbacks from human activity.

5Representative works are the classic Efficient Use of Energy: A Physics Perspective (American Physical Society / American Institute of Physics, 1975) and the recent, massive, Lawrence Berkeley Laboratory / International Agency collaboration, Indicators of Energy Use and Efficiency: Understanding the Link Between Energy and Human Activity (OECD / IEA 1997).

The new NIST human genome RMs increase the ability of DNA sequencing laboratories to be more confident in their reporting of true positives, false positives, true negatives and false negatives, and therefore, significantly improve genetic tests used for disease risk prediction, diagnosis, and progression tracking.

Using the natural human development process as a guide, the researchers developed ways to mature muscle cells in the laboratory to create muscle fibers that restore dystrophin, the protein that is missing in the muscles of boys with Duchenne.

However, the genetic techniques used to block Hhat in the laboratory are not possible with animal models or humans.

«This is the first study to demonstrate that functional muscle cells can be created in a laboratory and restore dystrophin in animal models of Duchenne using the human development process as a guide.»

Laboratory mouse models are commonly used to study A-T; however, mice with A-T do not experience the more debilitating effects that humans do.

While NASA tends to use the ISS as a research ground for human spaceflight, the National Laboratory has launched a wide range of basic and applied research and educational opportunities into low orbit, under the motto «off the Earth, for the Earth,» she said.

Specifically, the imaging agents developed in the laboratory for use in fluorescence molecular tomography, are now even being translated into the clinic for human diagnostic applications.

Its first target was the regulatory network involved in controlling the differentiation of THP - 1 cells, a line of human leukemia cells used in laboratory experiments.

That's because most studies on single human brain cells use dead rather than living tissue, and many others rely on cells from common laboratory animals, especially mice.

Fruit flies are small insects that are often used for genetic research as they reproduce quickly, are easy to breed in laboratory conditions and share many of the same fundamental mechanisms and pathways found in more complex organisms such as humans.

Nagrath, who directs Rice's Laboratory for Systems Biology of Human Diseases, found that some cancer cells are capable of using these information packets as a source of energy to fuel tumor growth.

But while most PDX mice are used as general models of human cancer in the laboratory, others seek to use them as Fiebig originally hoped — as avatars to guide customized patient care.

Dr. Chartoff's Neurobiology of Motivated Behavior Laboratory, founded in 2009, investigates the molecular, biochemical, and cellular mechanisms underlying drug dependence and withdrawal using animal behavioral models with high relevance to the human condition.

BPRC housing and animal care procedures comply with Dutch law, European Directive 2010 / 63 / EU, and with the «Standards for Humane Care and Use of Laboratory Animals by Foreign Institutions», identification number A5539 - 01, provided by the Department of Health and Human Services of the US National Institutes of Health.

The University of California, San Diego (UCSD) Human Stem Cell Core Facility, which supports multiple research projects using stem cells to advance the understanding and ultimately the treatment of disease and injury, will receive a $ 2.8 million Shared Research Laboratory Grant from the California Institute for Regenerative Medicine (CIRM).

There is increasing evidence in humans and laboratory animals for biologically - based sex differences in every phase of drug addiction including acute reinforcing effects, transition from occasional to compulsive use, withdrawal - associated negative affective states, craving, and relapse.

In their study, to be published in the online edition of the Proceedings of the National Academy of Sciences during the week of Jan. 26 - 30, researchers from Fukui Prefectural University in Obama, Japan, and the National Human Genome Research Institute (NHGRI), which is part of the National Institutes of Health (NIH), describe the innovative techniques they used to produce genetically modified zebrafish using sperm cells grown under laboratory, or «in vitro,» conditions.

Only a few laboratories in the world are attempting this technique in human stem cell research and, thus far, no human stem cell lines have been derived using this method.

This year has been an enormous step forward for us in developing the tools that we will use to transition our laboratory studies into human studies.