Sentences with phrase «laboratory uses proteomics»
The Speicher laboratory uses proteomics, metabolomics, computational methods, and biophysical approaches to characterize the roles of normal and mutant proteins in cancers and other human diseases.
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The research team identified over one thousand such proteins by using innovative proteomic methods, developed by Professor Matthias Hentze and colleagues from EMBL, which is Europe's flagship laboratory for the life sciences.
His laboratory uses a multidisciplinary approach encompassing systems biology, molecular pharmacology, biochemistry / proteomics, cell and structural biology, and computation / bioinformatics.
His laboratory is also keenly interested in utilizing high - throughput proteomic approaches for the discovery of biomarkers for diseases such as cancer and exploring the use of proteomic and metabolomic technology for the routine interrogation of clinical samples.
He was promoted to Director of Proteomics, where he designed and implemented a number of technologies currently used in many proteomics laboratories across Proteomics, where he designed and implemented a number of technologies currently used in many proteomics laboratories across proteomics laboratories across the world.
His laboratory uses integrated genomics and proteomics as well as computational methods to elucidate disease mechanisms and discover biomarkers for non-communicable and infectious diseases.
Results: Scientists at Pacific Northwest National Laboratory (PNNL) have reported the first systematic investigation using global proteomics to identify changes in the abundance of bacterial proteins associated with macrophage colonization and a new protein that helps the bacterium to survive inside macrophages.
Methods: The researchers used mass spectrometry - based proteomics at the U.S. Department of Energy's Environmental Molecular Science Laboratory, a national scientific user facility at PNNL, on platelets from healthy and type 2 diabetics collected at the University of Rochester Blood Bank.
Using state - of - the - art proteomics and associated computational methods, the Speicher laboratory is investigating protein changes associated with ovarian cancer, melanoma, cardiac injury resulting from breast cancer therapies, ectopic pregnancy, red cell diseases, and other clinical disorders.
My laboratory also conducts fundamental research using genetics, biochemistry, cell biology and proteomics to define mechanisms of ECM assembly and turnover and their effects on cell behavior.