Sentences with phrase «lack estrogen receptors»

The study found that curcumin is able to induce apoptosis (normal programmed cell death) in the most resistant breast cancer cells that lack estrogen receptors.

But recent work shows that while these cancers lack estrogen receptors, progesterone receptors, and aren't driven by the gene HER2, up to a third of these tumors express the androgen receptor — clinical trials are underway to inhibit the androgen receptor in these tumors in much the same way that the drug Tamoxifen inhibits estrogen receptor in estrogen - receptor - positive breast cancers.

Triple - negative breast cancers are those whose cells lack estrogen receptors and progesterone receptors, and do not have an excess of the HER2 protein on their surfaces.

Not exact matches

The draft lacks a clear description of the criteria for eliminating an increasing number of non-GLP studies that indicate the possibility of toxic effects that are not mediated by interaction of BPA with the estrogen receptor, and the Subcommittee does not agree with the exclusion of the non-GLP studies in the safety assessment.

Triple negative breast cancer is especially hard to treat because it lacks the receptors, such as the estrogen receptor, targeted with other cancer drugs.

It is called triple negative because it lacks receptors for the hormones estrogen and progesterone and makes little of a protein called HER2.

It derives its name from the lack of receptors for estrogen, progesterone and Her2.

They massively overexpress the estrogen receptor to compensate for a lack of estrogen.

Ince and his team found that although TNBC lacks the three receptors that fuel most breast cancers — estrogen receptors, progesterone receptors, and human epidermal growth factor receptor 2 — it does express androgen receptors (AR) and vitamin D receptors (VDR).

Triple - negative breast cancer (TNBC), a tumor type defined by its lack of estrogen receptor, progesterone receptor, and Her2 (ERBB2) amplification, accounts for 16 % of breast cancers.

Chemotherapy is a key part of the standard treatment regimen for triple - negative breast cancer patients whose cancer lacks expression of estrogen and progesterone receptors and the human epidermal growth factor receptor 2...

Despite marked advances in breast cancer therapy, basal - like breast cancer (BBC), an aggressive subtype of breast cancer usually lacking estrogen and progesterone receptors, remains difficult to treat.

Triple - negative tumors are in the 4th category, and are lacking receptors for estrogen, progesterone, and a protein known as HER2 / neu.