Lundblad's group has engineered yeast cells that
lack telomerase, to study how cells respond to eroding telomeres when telomerase is not present to counter-balance.
Scientists think that normal cells, which apparently
lack the telomerase enzyme, stop dividing and die off appropriately after 50 to 100 divisions when their telomeres are worn to the nub.
Several years ago, Ronald DePinho of the Dana - Farber Cancer Institute in Boston and his colleagues genetically engineered a strain of mice that
lacks telomerase.
Not exact matches
This widespread
lack of the need for
telomerase is used by evolution as a key component of our defense against cancer, because having a limit to the size and renewal of telomeres prevents our cells from replicating themselves indefinitely — the crucial hallmark of cancer.
In tomorrow's Cell, researchers describe how older mice
lacking the enzyme
telomerase — which helps protect dividing chromosomes — go prematurely grey and begin to lose their fur.
«The
lack of
telomerase results in the telomeres shrinking, which provides a way for the cells to mark time and age every time they divide.»
Lack of
telomerase activity in human mesenchymal stem cells.
Various types of meditation have been shown to improve well - being among different populations such as physicians and the general public.14, 15, 16 Preliminary evidence suggests that meditation - based interventions may slow cellular aging rates by increasing
telomerase activity, but many such studies
lacked an active control group.17, 18 Recent randomized trials in breast cancer suggest that long - term intensive meditation interventions might have positive effects on
telomerase activity.
The FTC charged
Telomerase Activation Sciences, Inc. and Noel Patton (collectively, TA Sciences) with
lacking the scientific evidence to support claims that their capsules, powders, and creams could provide a broad range of anti-aging and other health benefits.