Sentences with word «laminin»

As expected, additional experiments by Abe showed that the F1 - actin flow was dependent on L1 - CAM interactions with laminin.

Antibody - induced activation of betal integrin receptors stimulates cAMP - dependent migration of breast cells on laminin - 5.

Professor Karl Tryggvason discusses the use of biologically relevant human recombinant laminins from BioLamina that successfully recreates specific cell niches in the cell culture dish.

An expansive portfolio of chemically defined and xeno - free laminin proteins for a variety of cell culture applications

This form of muscular dystrophy results from a genetic defect in laminin - α2.

Human recombinant laminin isoforms are developed for defined and xeno - free stem cell culturing and primary cell cultures.

This protein, called laminin - α4, however, is only a poor replacement because it is not well integrated into the cell scaffolding.

When cultured upon selected combination of islet - specific laminins, pancreatic islets exhibited following effects: (1) robust spreading into flattened adherent clusters with heterocellular organization, (2) islets maintain functional ability for glucose - dependent insulin release, (3) all the endocrine cell types maintain specific markers expression and ability to proliferate.

Mutations in the LAMB3 gene prevented the boy from making laminin 332 protein (top middle, white dashed line indicates where the protein should be), which helps fuse skin layers together.

(D) Representative laminin - and H&E - stained EDL muscle sections demonstrate these morphological changes.

Biologically relevant laminins enable mouse pancreatic islets in vitro culture: expansion, phenotype maintenance and glucose - dependent insulin release.

Morphogenetic effects of soluble laminin - 5 on cultured epithelial cells and tissue explants.

Stem cell culturing of human ES and iPS cells on recombinant laminin matrices is easy and efficient.

Unless, of course, you can prove that the «apostle» Paul had knowledge of laminins during the time in which he lived?

«Laminins function as attractive chemical cues for haptotaxis of axonal growth cones,» explains NAIST Prof. Naoyuki Inagaki, whose lab studies how forces are generated in the cellular microenvironment to create directed axonal migration.

The different grip ratio seen between laminin and polylysine was lost, and the directional axon migration was disturbed,» said Inagaki.

Microscope images show that in normal skin (left) the top layer, called the epidermis (purple in bottom images), is fused to the dermis by laminin 332 (green, in top images) and other proteins.

Gene therapy (right panels show the boy's skin 21 months after therapy) restored laminin 332 (top, green) and his skin stopped blistering (bottom).

We now demonstrate that B. burgdorferi adheres to the extracellular matrix component laminin.

Giannelli G, Pozzi A, Stetler - Stevenson WG, Gardner HA, Quaranta V. Expression of matrix metalloprotease -2-cleaved laminin - 5 in breast remodeling stimulated by sex steroids.

ES derived hepatocyte differentiation on laminins represent significant improvement of metabolic activity and functional organisation

Laminins plays an important role in more and more applications moving into the regenerative medicine filed.

The cells were plated at a density of 2.5 × 105 cells / 0.2 ml on a glass - bottomed dish (35 - mm dish, 14 - mm coverglass, Mat Tek Co., Ashland, MA, USA) that was pre-coated with 0.1 mg / ml poly - L - lysine (Sigma - Aldrich) and 10 µg / ml laminin (BD Biosciences, Franklin Lakes, NJ, USA).

Tumor cell alpha3beta 1 integrin and vascular laminin - 5 mediate pulmonary arrest and metastasis.

and cultured in 5 % O2 / 7 % CO2 in Bottenstein - Sato F12 medium with 10 ng / ml human recombinant basic fibroblast growth factor (Peprotech) on a substrate of 1 µg / cm2 fibronectin (Chemicon) and 0.5 µg / cm2 laminin (Invitrogen).

Further experiments indicated that the cells would recover their normal behavior in high - stiffness gels if they were exposed to increasing concentrations of laminin, a protein naturally found in the basement membrane.

Laminin cell culture matrices — The key to efficient derivation and reliable culture of stem cells and specialized cells lies within these extracellular matrix proteins

Here, we show hES cells plated as single cells on top of recombinant laminin - 521, growing from day 0 to day 5 when they are ready to be split again.

Consequently, as a result of gene defects in laminin - α2 the muscles are extremely unstable and even normal use of the muscles leads to muscle injuries, inflammation and finally to the degeneration of muscle fibers.

The boy's mutation is in the gene LAMB3, one of three that instruct epidermis cells to make laminin - 332, a protein that links the layers.

(H) Representative laminin and H&E - stained TA muscle sections demonstrate these morphological changes.

Dr. Kristian Tryggvason tells the story about BioLamina and why biologically relevant laminins are the best matrix for cell culturing, including culture of stem cells and primary cells.

Rapid spreading and mature hemidesmosome formation in HaCaT Keratinocytes induced by incubation with soluble laminin - 5r.

Go to google images and type in «Laminin».

I ran accross the laminin thing on the internet and wanted to see the reactions it stirred up.

You need to look at this cross-shaped diagram of a laminin protein and then you'll no longer doubt God.»

I challenge anyone to google «Laminin» if you want biological proof of God... read what the function of this protein is... then go read Colossians 1:17... GO DO IT RIGHT NOW!

Now they report recovering not just collagen — which conveys little evolutionary information because it is the same in almost all animals — but also haemoglobin, elastin and laminin, as well as cell - like structures resembling blood and bone cells.

They found very similar structural defects and laminin - α4 was also found in place of laminin - α2 in the diseased muscle fibers.

The researchers designed two proteins that allow the integration of laminin - α4 and anchor it to the muscle cell.