Sentences with phrase «large animal model of the disease»
«The dog has a retina very similar to ours, much more so than mice, so when you want to bring a visual therapy to the clinic, you want to first show that it works in a large animal model of the disease,» said lead researcher Ehud Isacoff, professor of molecular and cell biology at UC Berkeley.
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«We report here a gene therapy dose - finding study in a large animal model of a severe muscle disease where a single treatment resulted in dramatic rescue,» said Childers.
«Large animal models of human disease, like cats, are really helpful for determining what's going to happen in a child when you're treating them,» Vite said.
These findings are promising for developing a preclinical, large animal model of Huntington's disease for assessing new therapeutics, which could ultimately provide better treatment options, including altering the course of the disease.
Our finding of similarity in clinical progression between human patients and Huntington's disease monkeys suggests monkeys could become a preclinical, large animal model for the development of new treatments.»
The CRISPR - Cas technology generates specific animal models of disease and is transforming model generation in mice, rats, rabbits, and larger animals.