Sentences with phrase «large association study»

Reykjavik, ICELAND, December 13, 2002 — deCODE genetics (Nasdaq / Nasdaq Europe: DCGN) announced today that a large association study carried out by its scientists and colleagues in Scotland has confirmed the significant link between the Neuregulin 1 gene and...

One of the largest association studies of the recent past has come from analysis of the data by combining three very large cohort studies — the Nurses Health Studies I and II as well as the Health Professional's Follow Up study.

Not exact matches

Using data from a large - scale study that tracked participants» diet and health information for more than a decade, researchers found an association between moderate chocolate consumption and a lowered risk for atrial fibrillation.

Studies have shown a fairly large percentage of employees are stressed about their financial situation, and worried about not having enough money to retire, said Todd Saulnier, vice-chair of the national policy committee at the Association of Canadian Pension Management (ACPM) in Halifax.

Now, he testified: «A very large majority of studies report a positive association between exposure to media violence and aggressiveness.

Finally, we have reviewed a large - scale study on high blood pressure showing an association between high levels of protein intake (in the vicinity of 100 grams per day) and significantly decreased risk of high blood pressure over an 11 - year period of time.

One study finds an association with disease x, but not y or z, another finds one with y but not x. None of these studies are able to fully control for the critically important confounding variable of maternal health, and none of the decent quality ones have demonstrated a large difference in risk.

Furthermore, there has been no large - scale study of the impact of this intervention on breastfeeding initiation and duration, although a study based in Scotland has provided some evidence for an association between birth in a Baby Friendly facility and increased rates of breastfeeding at 1 week of age.16, 17

«106 Some medical researchers preferred commercial baby food because its large - batch preparation allowed for nutritional uniformity, an asset to their research studies.107 The American Medical Association's Council on Foods, a governing body of doctors, in 1937 issued a report on infant feeding of fruits and vegetables.

Yet another large study in 1987 showed no association between twins and taking oral contraceptives.

My comment came from the finding that preemies are at higher risk of SIDS, and some studies find an association with bedsharing among preemies that is larger than that of term babies.

Some of these studies involved large representative samples from the United States; 2 some studies controlled for potential confounders, such as parental stress3 and socioeconomic status; 4 and some studies examined the potential of parental reasoning to moderate the association between physical punishment and child aggression.5 Virtually without exception, these studies found that physical punishment was associated with higher levels of aggression against parents, siblings, peers and spouses.

In addition, there was no effect on breastfeeding duration when the pacifier was introduced at 1 month of age.280 A more recent systematic review found that the highest level of evidence (ie, from clinical trials) does not support an adverse relationship between pacifier use and breastfeeding duration or exclusivity.281 The association between shortened duration of breastfeeding and pacifier use in observational studies likely reflects a number of complex factors such as breastfeeding difficulties or intent to wean.281 A large multicenter, randomized controlled trial of 1021 mothers who were highly motivated to breastfeed were assigned to 2 groups: mothers advised to offer a pacifier after 15 days and mothers advised not to offer a pacifier.

Breastfeeding is associated with about 10 % lower maternal risk of several major cardiovascular diseases (CVDs) in later life, and the magnitude of the inverse association was stronger among those with a longer duration of breastfeeding, according to a large, prospective, observational study among Chinese women.

Two later studies not included in these meta - analyses reported equivalent or even larger protective associations.265, 266 The mechanism for this apparent strong protective effect is still unclear, but lowered arousal thresholds, favorable modification of autonomic control during sleep, and maintaining airway patency during sleep have been proposed.247, 267, — , 270 It is common for the pacifier to fall from the mouth soon after the infant falls asleep; even so, the protective effect persists throughout that sleep period.247, 271 Two studies have shown that pacifier use is most protective when used for all sleep periods.169, 266 However, these studies also showed increased risk of SIDS when the pacifier was usually used but not used the last time the infant was placed for sleep; the significance of these findings is yet unclear.

Commenting on the study, ESMO spokesperson Dirk Arnold, MD, PhD, from Instituto CUF de Oncologia in Lisbon, Portugal, said «this large population - based cohort - control study impressively confirms the hypothesis of an association of colorectal polyps with diets and other life - style factors.

A large study published last month in The Journal of the American Medical Association found that beta blockers did not prolong the lives of patients — a revelation that must have left many cardiologists shaking their heads (JAMA, vol 308, p 1340).

The authors conclude: «The findings from this large prospective study show that the association between body size and prostate cancer is complex and varies by disease aggressiveness; men who have greater adiposity have an elevated risk of high grade prostate cancer and prostate cancer death.»

The association recently gave Bowser funds for an expanded study, to see whether the biomarkers hold up in a larger population.

African populations harbour the greatest genetic diversity and have the highest per capita health burden, yet they are rarely included in large genome studies of disease association.

New research published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that age (or age at diagnosis) and duration of diabetes disease are linked to the risk of death and marcovascular complications (those in larger blood vessels), whereas only diabetes duration is linked to the risk of microvascular complications (in smaller blood vessels such as those in the eyes).

If the association holds up in larger studies, Chatila says, doctors could use the information to sort out which mutation — or combination of mutations — leads to different kinds of allergic diseases.

Based on these points, Dr. Canli suggests a major research step would be to conduct large - scale studies with depressed patients, controls, and infectious - disease related protocols to determine the association or causal nature of infectious disease and depression.

The association study matches genetic variants with a trait by looking at large groups of people with that trait and then compares how their genomes differ from a group without the trait.

Given their different physiology and risk factors, we have conducted the first large prospective study on the association of fruit with subtypes of stroke in Chinese adults from both rural and urban areas.»

Of these twelve genetic regions, six are also associated with IBD, while the six other regions showed little to no association in a recent large study of IBD.

AERA is the largest interdisciplinary research association in the United States devoted to the scientific study of education and learning.

In the first study to report on the association of aspirin use with breast cancer outcomes in a large patient population, researchers examined the pattern of aspirin use, cancer pathology and overall survival in 1,000 patients treated at the Abramson Cancer Center of the University of Pennsylvania and diagnosed with breast cancers, including receptor positive, HER2 - positive and triple negative cancers.

For pregnant women who are at low risk of complications giving birth, the risk of newborn death and maternal complications is similar for obstetric deliveries by family physicians and obstetricians, according to a large study published in CMAJ (Canadian Medical Association Journal).

According to the researchers, this is the first large - scale study employing epigenome - wide association (EWAS) studies — which look at chromosomal make - up and changes — in relation to the brain and Alzheimer's disease.

So a team of US and German researchers carried out a large prospective study to evaluate associations between migraine, cardiovascular disease and mortality.

In an accompanying editorial, Lawrence J. Schweinhart, Ph.D., of the HighScope Educational Research Foundation, Ann Arbor, Mich., writes that although the associations found in this study were statistically significant, «they may not be substantial enough to justify the larger expense of full - day preschool, essentially twice that of part - day preschool.»

Reporting today in the Journal of the American Medical Association, a team of scientists from the Women's Health Initiative Memory Study (WHIMS), a subset of the larger Women's Health Initiative, report that Prempro provides no boost to cognition or protection against dementia in women 65 years of age and older.

Their study — «Using Facebook to Engage Learners in a Large Introductory Course» — was published in Teaching Sociology, a journal of the American Sociological Association.

To date, the present study is the largest to investigate the association between levels of long - chain omega - 3 and omega - 6 fatty acids in the blood and subsequent development of asthma and other allergic diseases.

The Wellcome Trust, the U.K.'s largest biomedical charity, began to put its weight behind genome - wide association studies in 2005 and recruited 200 researchers to analyze the DNA of 17,000 people from across the United Kingdom.

Now results from the first large population study conducted to assess the association show that older age at natural menopause and the use of oral HT are each associated with a higher risk of hearing loss.

So a team of scientists, led by Lucy Bowes at the University of Oxford, carried out one of the largest studies on the association between bullying by peers in teenage years and depression in early adulthood.

«This is the largest study addressing the association of gum disease and cancer risk using dental examinations to measure gum disease prior to cancer diagnosis,» said first and corresponding author Dominique Michaud, Sc.D., professor of public health and community medicine at Tufts University School of Medicine.

The second tool, SuperExactTest, establishes the very first theoretical framework for assessing the statistical significance of multi-set intersections and enables users to compare very large sets of data, such as gene sets produced from genome - wide association studies (GWAS) and differential expression analysis.

«The study represents the largest cohort of patients with OACICH to date and reports 2 clinically valuable associations.

«Given the expanding prevalence of shift work worldwide and the heavy public burden of cancers, we initiated this study to draw public attention to this issue so that more large cohort studies will be conducted to confirm these associations,» he added.

Chlorpyrifos exposure had a larger association with working memory scores in the boys, who averaged three points lower than the girls with similar exposures, the study found.

One of the largest studies carried out to date in order to determine mercury levels in umbilical cord blood samples and its association with different reproductive effects: measurements of fetal development (weight, height and head circumference at birth), placental weight, duration of pregnancy and risk of premature birth.

Professor Jeremy Pearson, Associate Medical Director at the BHF, which part - funded the study, said: «By using the power of very large scale genetic studies, this research is the first to show that the known association between increased height and a lower risk of coronary heart disease is at least in part due to genetics, rather than purely down to nutrition or lifestyle factors.

The study is the first to analyse the association between sleep duration and serum micronutrient concentrations in a large sample, and it found a link between high serum copper concentration and long sleep duration.

This is the first study to examine the association between the risk of complications after surgery and the rate of unplanned re-hospitalizations in a large, nationally representative sample of patients undergoing general surgery.

Although several case reports have indicated that there may be an association between use of HRT and risk of acute pancreatitis, the evidence from large studies is sparse.

Indeed, research doesn't always support the notion that salt causes high blood pressure: A large, multicenter study known as INTERSALT compared urinary sodium levels — an accurate indicator of prior sodium consumption — with hypertension in more than 10,000 people in 1988 and found no statistically significant association between them.

«Epidemiological studies look for associations in large populations, but it is usually difficult to reliably determine cause and effect — what we call causality.