Sentences with phrase «large cohort studies of»

Several large cohort studies of medical x-ray technicians and nuclear industry workers suggest a slight increase in cancer risk at exposures below 100 mSv, Shore says.
Our study adds to the body of large cohort studies of planned home births that have reported on the relative safety of home versus hospital birth.
The study adds to the body of large cohort studies of planned home births that have reported on the relative safety of home versus hospital births.
ACCHS provide comprehensive primary healthcare to Aboriginal people in a culturally appropriate manner.14 The children participated in phase I of the Study of Environment on Aboriginal Resilience and Child Health (SEARCH), the largest cohort study of urban Aboriginal children ever conducted.15 Specifically, we aim to describe:

Not exact matches

A study published in 2000 by the ELCA revealed that of the cohort of newly minted pastors, 71 percent placed constraints upon where they could move due to the needs or desires of a spouse; 58 percent restricted their first call to a location in or near a large city; 36 percent were opposed to serving in a small congregation; and 32 percent were opposed to serving in a rural setting.
Last week, we posted to the site a group of four articles about a peer - reviewed study in the Journal of Neurosurgery showing that football helmet design affected concussion risk among a large group (or what scientists call a «cohort») of college football players.
Most studies of homebirth in other countries have found no statistically significant differences in perinatal outcomes between home and hospital births for women at low risk of complications.36, 37,39 However, a recent study in the United States showed poorer neonatal outcomes for births occurring at home or in birth centres.40 A meta - analysis in the same year demonstrated higher perinatal mortality associated with homebirth41 but has been strongly criticised on methodological grounds.5, 42 The Birthplace in England study, 43 the largest prospective cohort study on place of birth for women at low risk of complications, analysed a composite outcome, which included stillbirth and early neonatal death among other serious morbidity.
The strength of this study is its prospective population - based cohort design with a large number of subjects and the possibility to adjust for all major confounders.
An UpToDate review on «Planned home birth» (Declercq and Stotland, 2015) stated that «Large cohort studies using intent - to - treat analysis of midwife - attended, planned, out - of - hospital birth of low - risk women in developed countries have reported reduced rates of cesarean birth, perineal lacerations, and medical interventions, and similar rates of maternal and early perinatal morbidity and mortality compared to planned hospital birth.
When logistic models were stratified by the presence or absence of hypertensive disease, only maternal age older than 34 years (odds ratio [OR], 1.4; 95 % confidence interval [CI], 1.0 - 2.0), pregnancy - associated plasma protein - A of the 95th percentile or less (OR, 1.9; 95 % CI, 1.2 - 3.1), and alpha fetoprotein of the 95th percentile or greater (OR, 2.3; 95 % CI, 1.4 - 3.8) remained statistically significantly associated for abruption.In this large, population - based cohort study, abnormal maternal aneuploidy serum analyte levels were associated with placental abruption, regardless of the presence of hypertensive disease.
This also was found in a large, retrospective cohort study of 15,759 nulliparous women even in a group of women whose second stage progressed beyond 4 hours (29).
«For this large cohort of women who planned midwife - led home births in the United States, outcomes are congruent with the best available data from population - based, observational studies that evaluated outcomes by intended place of birth and perinatal risk factors.
Studies also suggest a potential role for selected probiotics in atopic dermatitis prevention, and future studies will need to standardize the probiotic strain as well as amount used in a larger cohort of pregnant women in order to better assess these eStudies also suggest a potential role for selected probiotics in atopic dermatitis prevention, and future studies will need to standardize the probiotic strain as well as amount used in a larger cohort of pregnant women in order to better assess these estudies will need to standardize the probiotic strain as well as amount used in a larger cohort of pregnant women in order to better assess these effects.
Commenting on the study, ESMO spokesperson Dirk Arnold, MD, PhD, from Instituto CUF de Oncologia in Lisbon, Portugal, said «this large population - based cohort - control study impressively confirms the hypothesis of an association of colorectal polyps with diets and other life - style factors.
While further study of larger patient groups with longer follow - up times is needed for this cohort of prostate cancer patients, this study is pivotal in providing evidence for change in practice.»
Additional studies in larger cohorts will be needed to validate these findings, and more biomarkers will be needed to get the completely accurate set needed to screen the general population with the long term goal of identifying precursor lesions before they become malignant.
Data was gathered on 2,424 participants of the Rotterdam study, a large population - based cohort study including participants 45 years or older living in a suburb of Rotterdam, The Netherlands.
To identify the relevant mutations the scientists analyzed the blood samples of 1,858 men from three independent cohorts in Europe and North America: the Swiss arm of the European Randomized Study for Prostate Cancer Screening, the large American Screening trial, Prostate, Lung, Colorectal, and Ovarian (PLCO), Princess Margaret Cancer Centre (University Health Network) and Mount Sinai Hospital (Sinai Health System) in Toronto.
A phase II basket study is ongoing to determine whether these early results can be confirmed in a much larger cohort of patients.
The Chronic Hepatitis Cohort Study is an analysis of records from a large, geographically and racially diverse group of 9,783 patients receiving care at four large U.S. health systems: Henry Ford Health System in Detroit; Kaiser Permanente Northwest in Portland, Oregon; Kaiser Permanente in Honolulu and Geisinger Health System in Danville, Pennsylvania.
Findings from this UK cohort are confirmed by evidence for adult - onset ADHD world - wide: a study from Brazil will be published by JAMA Psychiatry alongside this research, which also identified a large proportion of adults with ADHD as not having the disorder in childhood.
Similar cohort studies sponsored by the National Heart, Lung, and Blood Institute are confronting a similar fate and some observers suggest that the era of such large, costly long - termstudies is drawing to a close.
Adams points out that Cohort A is the first phase II study of an immunotherapy for triple negative breast cancer to be reported and represents the largest cohort of patients with mTNBC treated with immunotherapy toCohort A is the first phase II study of an immunotherapy for triple negative breast cancer to be reported and represents the largest cohort of patients with mTNBC treated with immunotherapy tocohort of patients with mTNBC treated with immunotherapy to date.
Young adults with thinner cortex in particular brain regions are more impulsive during a decision - making task than teens with thicker cortex, according to a large correlational study of adolescents from the Philadelphia Neurodevelopmental Cohort.
The researchers analysed data from a large Norwegian population - based pregnancy cohort study called MoBa, which involves a range of data collected from mothers and children during and after pregnancy.
This is the largest cohort study to analyze changes in rates of pre-eclampsia in the U.S.
From this survey data, NASA's James Webb Space Telescope as well as large ground - based observatories will be able to further characterize the targets, making it possible for the first time to study the masses, sizes, densities, orbits, and atmospheres of a large cohort of small planets, including a sample of rocky worlds in the habitable zones of their host stars.
Dr. Zhang points out that the unique value of this study derives from the ability to perform longitudinal assessments of cognition in PD patients over a long time period and access to data from a large cohort that began when patients were in the earliest stage of disease.
Dr Matt Hurles, who led the study from the Sanger Institute, said: «This study has the largest cohort of such families in the world, and harnesses the power of the NHS, with 200 clinical geneticists and 4,000 patients.
Researchers expect the data presented in this study to fuel the formation of large national and international research consortiums to conduct comprehensive, systematic analysis of inherited (germline) genome data in large cohorts of uveal melanoma patients.
The cohort program is the largest piece of the PMI: A 1 - million - volunteer health study that will probe the interplay among genetics, lifestyle factors, and health.
Researchers were able to access CSF samples from the deprenyl and tocopherol antioxidative therapy of Parkinsonism (DATATOP) study, which is the largest cohort assembled to date with longitudinal collection of biological fluids and clinical data from PD patients.
The aim of this new study was to determine whether 2D: 4D was associated with the risk of severe knee or hip OA requiring total joint replacement in a large cohort study.
Nechuta and colleagues used data from the Shanghai Women's Health Study, a large, population - based prospective cohort study of about 75,000 women ages 40 to 70, from Shanghai, China, led by Wei Zheng, MD, PhD, at the Vanderbilt Epidemiology CeStudy, a large, population - based prospective cohort study of about 75,000 women ages 40 to 70, from Shanghai, China, led by Wei Zheng, MD, PhD, at the Vanderbilt Epidemiology Cestudy of about 75,000 women ages 40 to 70, from Shanghai, China, led by Wei Zheng, MD, PhD, at the Vanderbilt Epidemiology Center.
«The study represents the largest cohort of patients with OACICH to date and reports 2 clinically valuable associations.
«Given the expanding prevalence of shift work worldwide and the heavy public burden of cancers, we initiated this study to draw public attention to this issue so that more large cohort studies will be conducted to confirm these associations,» he added.
According to Eva S. Schernhammer, MD, DrPH, currently Associate Professor of Medicine, Harvard Medical School, and Associate Epidemiologist, Department of Medicine, Brigham and Women's Hospital, Boston, this study «is one of the largest prospective cohort studies worldwide with a high proportion of rotating night shift workers and long follow - up time.
For this population - based research, investigators pooled data from large cohort studies conducted in Asia and included demographic and risk factor information collected in seven Asian regions from the early 1960s through the late 1990s (although most of the studies enrolled participants after the mid-1980s).
Conducting a cross-sectional study of a large cohort of patients with different levels of cognitive impairment and different disease stages, the researchers found that the amounts of a TREM2 fragment in the cerebrospinal fluid were highest during early stages characterized by mild cognitive impairment symptoms.
The study comprised data from three large cohorts, where individuals were subjected to repeated lung function measurements over the course of many years.
Several countries, including the United Kingdom and Estonia, have assembled similar studies of large groups of people, or cohorts, that collect DNA and health information on volunteers in repositories, sometimes called «biobanks.»
This study represents the largest reported cohort of CRC patients diagnosed in this age range in the U.S.
They are now in their 25th year of follow - up as part of a large, prospective cohort study.
Researchers believe it is the largest epigenetic study yet for any single cancer type and, importantly, the first to use a large cohort of primary patient tumor tissues instead of cell lines grown in the laboratory.
The Columbia researchers with colleagues in Finland conducted an analysis of data from the Finnish Prenatal Study of Schizophrenia, a large, national birth cohort with an extensive bio-bank.
Our study is one of the largest to explore the efficacy and safety of anti-TNF therapy in a large independent cohort of JDM patients.»
Of the dozen of these metabolites that were measured in cohorts from the longitudinal Framingham Heart Study (the long - term 1948 study to identify the common contributive factors of cardiovascular disease by following its development in a large subject group) levels of glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the studOf the dozen of these metabolites that were measured in cohorts from the longitudinal Framingham Heart Study (the long - term 1948 study to identify the common contributive factors of cardiovascular disease by following its development in a large subject group) levels of glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the studof these metabolites that were measured in cohorts from the longitudinal Framingham Heart Study (the long - term 1948 study to identify the common contributive factors of cardiovascular disease by following its development in a large subject group) levels of glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the sStudy (the long - term 1948 study to identify the common contributive factors of cardiovascular disease by following its development in a large subject group) levels of glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the sstudy to identify the common contributive factors of cardiovascular disease by following its development in a large subject group) levels of glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the studof cardiovascular disease by following its development in a large subject group) levels of glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the studof glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the studof fitness, as measured in the studystudy.
Limitations of the study included the small number of participants; the authors advise that the study should be replicated ideally with a larger cohort.
Researchers analyzed data from a large national birth cohort of pregnant women who participated in the Finnish Prenatal Study of Schizophrenia and their offspring from the Finnish Maternity Cohort, which archived over 1 million prenatal serum specimens sincecohort of pregnant women who participated in the Finnish Prenatal Study of Schizophrenia and their offspring from the Finnish Maternity Cohort, which archived over 1 million prenatal serum specimens sinceCohort, which archived over 1 million prenatal serum specimens since 1983.
She and her team had previously analyzed blood samples of children in a biobank established by Professor Anette - Gabriele Ziegler, director of the IDF, within the framework of large - scale cohort studies.
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