Sentences with phrase «large dollar holdings»

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These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Gold fell as the dollar held near the highest level in five years and investors reduced holdings in the largest exchange - traded product backed by the metal, curbing demand for a store of value.

In the wake of the U.S. Department of Commerce's announcement of the countervailing duties on Canadian softwood lumber Tuesday, the Canadian dollar fell due to expectations of large job losses that could begin to take hold as early as this fall.

Credit Suisse Credit Suisse, the Fund's largest holding, had a volatile quarter due to recent news, but it ended the quarter with a gain of 6.5 % in U.S. dollar terms over the period.

A large part of the Dollar's strength (beyond «just» the data) post - the election has been based upon this, where if the corporate tax rate were cut to say 20 %, the Dollar would by economic theory have to then appreciate 20 % (and of course too, an additional «tax factor» driving the USD bull - thesis is that a meaningful chunk of $ 2.5 T of profits held overseas by US corporates would be repatriated following a «business friendly» incentive package / one - time cut to the repatriation tax to say 8 - 10 %).

The clearest available explanation for this crazy price outcome is supply: the total dollar amount of market value in $ WFC - L, an amount that has to find a home in someone's portfolio at all times, is roughly 1000X larger than the total amount of $ KSU - to be held.

The offering, which was sold as a private placement, was the largest dollar - denominated corporate bond sale since Roche Holding issued $ 16.5 billion of debt in February 2009.

A large exchange might be holding hundreds of millions of dollars worth of cryptocurrency.

I'd bet my bottom dollar that if Asano or Holding had turned us down this summer there'd be headlines of: «Japanese wonderkid having brilliant Olympics turned down chance to join Wenger and Arsenal»» U19 English international and Bolton's player of the season having a great tournament turned down Gunners» And a large portion of the fanbase would be lapping it up and joining in any excuse to criticize..

For some inexpensive Halloween decor head to the dollar store and pick up a plastic skull and turn it into a creepy gold candle holder perfect for holding a large pillar candle.

Get an assortment of balls (available at the dollar store), like those odd - textured koosh balls, a stress - reducing hand - held ball which can be squeezed, balloons, a large beach ball or a stress - relieving exercise balls on which a child can sit when they get fidgety.

Produced by Jimmy Siegel, a noted political adman, the ad cost hundreds of thousands of dollars and comes as charter operators are set to hold a large rally on September 30, according to Politico New York.

WHEREAS, women make up 50 % of the population in Santa Clara County but face significant economic disparities, with an average pay difference that is larger than the national wage gap of $.72 for a man's dollar, with women holding advanced degrees earning roughly $ 40,000 less than their male counterparts, and 11 % of the County's female population living in poverty and approximately 33 % of the homeless population being women and girls, and

Lipper published a study several years ago that estimated the average mutual fund carries transaction expenses of about 0.15 % per year - which can cost investors with larger share holdings thousands of dollars over time.

With interest rates nearly zero at present, people are directly and indirectly holding much larger amounts of base money, currently slightly more than 13 cents for every dollar of GDP.

Many small countries will peg their currency's value to that of the US dollar, whilst global banks will hold a large portion of currency reserves in US dollar.

It presumes that (i) when comparing the outcomes from using different accounts it is necessary to presume that all savings go into those accounts, (ii) when wages and living expenses are held constant between options, any option that reduces taxes should result in larger savings, (iii) the RRSP's benefits accrue only to the dollars in the account.

Penny stocks are sub one dollar priced, typically small companies which in theory can grow to be large companies, but the available information tends to be tougher to get hold of.

The emerging evidence is that this particular investor cohort has earned negative dollar - weighted alphas on a gross - of - fee basis, as indicated by their large negative return gaps versus a buy - and - hold strategy.

In fact, large or small, value or growth, investors» dollar - weighted returns are overwhelmingly lower than the fund managers» buy - and - hold or time - weighted returns.

Net effect: larger holding of a good company with a dollar - cost averaged purchase price and decreased average commissions / fees.

From an investment perspective, it's often best to have larger dollar figures to invest and help truly diviersify holdings.

The fund's largest holdings include the usual suspects — government bonds, a couple of ETFs (Canadian Dollar hedged, of course), and banks that aren't Bank of Montreal, because apparently this fund manager WANTS to get fired.

There may be some risk to holding a large amount of assets in foreign currencies, since you are still dependent on the strength of the Canadian dollar when you receive dividends or sell the assets.

Corporate leaders, government ministers and international development banks leading the transition to a green economy were also in Paris to highlight the multi-trillion dollar business opportunities in responding to climate change at the Sustainable Innovation Forum, the largest business - focused event held during the COP21 Paris Climate Summit.

And there's often more at stake, because if the privately - held farm goes under, a family's livelihood is potentially destroyed, whereas if a CEO at a large public company pulls off a terrible merger, he lies low for a while, and re-emerges at another Fortune company on a multi-million dollar salary.

Tanya Viner's practice focuses on mergers and acquisitions, representing both the buyer and seller in large complex transactions ranging from the sale of closely - held family businesses to transactions in excess of a billion dollars.

Investment of premium dollars is, of course, one way that insurance companies can take small premiums and hold out the promise of large death benefits.

A large exchange might be holding hundreds of millions of dollars worth of cryptocurrency.

Banks and thrifts saw the largest increase in dollar terms in their holdings of commercial / multifamily mortgage debt at $ 16.3 billion, or 1.8 percent.

As a result, the million - dollar home no longer holds the same cache it once did and in larger markets such as Vancouver, Calgary and Toronto, it's simply a starting price.»