Sentences with phrase «large durations of time»

«Advances in numerical algorithms, automatic grid generation, and increased supercomputer power will eventually make the simulations of flood waves over large durations of time possible using Titan, and even more so with Summit,» Constantinescu said.

You are responsible for not only what happens inside that room (a small duration of time) but also what happens outside of it (a larger duration of time).

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Transfer to a large baking sheet spreading out evenly and bake for 1 hour tossing the granola 3 - 4 times for the duration of the cooking time.

However, compared to previous studies of regulation compliance that have utilised data sets ranging in duration from 63 hours [9] to 80 hours of programming [24], this was a relatively large sample that was purposively selected to cover both school holidays and term time.

Perhaps the most tangible change to intelligence work addressed in Obama's speech is the end of the Section 215 program — which enables the government to collect large volumes of metadata, including phone numbers as well as the time and duration of calls.

The individual durations of the first pull, transition, second pull, turnover, and catch phases of the snatch are around 0.45 — 0.55, 0.1 — 0.15, 0.15, 0.25, and 0.30 — 0.35 seconds, respectively (Gourgoulis et al. 2002; Campos et al. 2006; Gourgoulis et al. 2009; Harbili, 2012), with no differences between successful and unsuccessful lifts (Gourgoulis et al. 2009) but with heavier athletes and heavier loads spending a larger proportion of total lift time in the first pull (Campos et al. 2006; Hadi et al. 2012).

According to this graph, rats fed an amount of protein that Harlan and the scientific community in general consider adequate (18 %) grow from 50 grams to over 100 grams during the course of time corresponding to the duration of Campbell's study, indicated by the large red bracket.

Over a short duration of time, we have established a strong academic base and have given satisfactory results to a large number of students.

Results of the present study indicate that a large percentage of healthy dogs have serum antibody titers to CPV and CDV, regardless of duration of time since last vaccination.

A private service will allow for a customized tour in which you can choose the sites you wish to visit, as well as the duration of the visit in each case, not being subject to a larger group itinerary and timings.

Players are encouraged to share, stream, record and discuss their experiences with Quake Champions freely for the duration of the large scale tech test limited - time open beta thing.

With the exception of Scandinavia, the duration of the largest droughts in Europe will also last three to four times longer than in the past.

Most Arizona judges consider a marriage lasting between ten to fifteen years to be marriages of moderate duration, which may justify a larger award of alimony for a greater length of time.

«Life + 70 years» is the duration under current US law, however, copyright in the US has been subject to a large number of durations at different times.

Because the reversion often needs to be discounted over a long period of time — over the duration of the existing lease — small changes in the deferment rate can cause large changes in the end valuation.