Sentences with phrase «large effect on the resulting»

Co-ingestion of foods that include fibre, fat and vinegar has a large effect on the resulting increase in blood glucose.

«Who gave up and who kept on could have a large effect on the results.

Do the MBH98 problems have a larger effect on the result?

I am fairly sure their error bars don't take these a priori uncertainties into account, but they have a lengthy discussion that says aerosols could conceivably have a large effect on their results if correlated with surface temperature.

Not exact matches

School - based programs that encouraged more physical activity also had no effect on BMI, one large review concluded, though other positive results — like lower blood cholesterol and less time spent watching TV — were observed.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

In 2014, Living Goods informed us that the results of the RCT were available and that the effect on mortality was large enough to overcome the problems with statistical power.

In terms of effect on consumption, Ng et al estimated a reduction in sugar sweetened drink intake of 104 mL (10 %) per person per week compared with our predicted reduction of around 15 %.19 The substitution effects predicted in Ng et al's study are very slight, and as a result the predicted change in energy intake is larger (net decrease of 24 kJ / person / day compared with our estimate of 17 kJ / person / day).

The drought in California does not appear to have had a major effect on this years» crop, but many fear that continuing lack of rainfall could have a large impact on 2015 results.

Thus, a baby born to a mother on this drug during the pregnancy, will have large amounts in his body, and even the small amount added during breastfeeding may result in significant accumulation and side effects.

A small number of secondary prevention programs for fathers of young children have been conducted and evaluated.18 For example, Parent — Child Interaction Therapy (PCIT), a short - term, evidence - based, training intervention for parents dealing with preschool children who display behavioural problems was evaluated in the Netherlands using a quasi-experimental design.19 The results showed a large effect on fathers» reports of child behaviour problems at the completion of the intervention.

The arbitrary thresholds your refer to are a problem, because they will have a distorting effect on the election result, especially if a large number of voters support minor parties, and therefore have their votes discarded when the final count is done.

Subsequent research undertaken at the University of Glasgow has indicated that such health inequalities may be due, at least in part, to epigenetic effects resulting from socio - economic circumstances - http://medicalxpress.com/news/2012-01-health-inequalities-imprinted-dna.html The Economic and Social Research Council (ESRC) is the UK's largest organisation for funding research on economic and social issues.

But ultimately she was both too new to the area and too liberal for much of the district — even though a portion of it featured some of Teachout's best results during her 2014 gubernatorial bid — and attack ads may have had a larger effect on her than on a longtime resident and political figure in Faso.

Early results from a larger, ongoing study led by environmental health scientist Richard Pilsner at the University of Massachusetts Amherst suggest that phthalate levels in expectant fathers have an effect on couples» reproductive success via epigenetic modifications of sperm DNA.

Though the researchers can't disclose the results for individual outlets for confidentiality reasons, they could show that removing larger outlets from the analysis didn't change the effect on public conversation much, suggesting that no single large news organization was responsible for the increase.

Honorton concluded that the results showed a large effect, unrelated to the quality of the study and not dependent on any one researcher.

«The results in our study are very similar to those obtained in a large European randomized clinical study (ERSPC) thus confirming the effect of PSA testing on the risk of prostate cancer death.

«Although this study demonstrates that atrasentan treatment results in clinically significant albuminuria reduction with minimal fluid overload - related or cardiovascular side effects, a larger study on hard renal and / or cardiac outcomes is needed to further support these findings,» said Dr. de Zeeuw.

«The researchers also calculated the likely effect of remediation on the ozone layer, but found that ozone depletion would be short - lived and similar to that resulting from natural processes such as large solar storms and volcanic eruptions.»

He tells Newsweek the findings play into a bigger picture, where we see large volcanic eruptions having an impact on the global climate that causes a chain effect resulting in social unrest.

Ricke and Caldeira sought to correct that by combining the results from two large modeling studies one about the way carbon emissions interact with the global carbon cycle and one about the effect of carbon on the Earth's climate used by the Intergovernmental Panel on Climate Change.

Complex questions such as these are addressed by biological systems science, where these results can be used to understand the effects of genetic perturbations on inherited and expressed characteristics in a larger context.

Using individual - level data from 335,464 participants in the UK Biobank and summary association results from seven large - scale genome wide association studies, we examined the effect of this nitric oxide signaling score on cardiometabolic and other diseases.

Presenting results as hazard ratios or relative risks always makes effects look large — «a 30 per cent heightened risk of developing type 2 diabetes» sounds like a big effect but based on figure 2 it looks like statins may be associated with an increase in the annual rate of new diabetes from about 6 per 100 people to approximately 8 per 100 people over a 10 year period.

And since strongman training takes everything on a whole new level, it also has a great effect on the rate of fat burning, due to its ability to boost the metabolism and result in a large accumulation of lactate in the body.

«Our results will need to be replicated in a larger sample to document the effects of mind - body approaches on stress reduction and depression prevention in this difficult - to - manage population.»

For answers, we will have to wait for results from large - scale, randomized control experiments exploring the effects of keto on mood swings in bipolar disorder.

This most recent study discovered that many psoriasis and psoriatic arthritis patients living in America in particular, are unhappy with their current treatments, and dissatisfaction with the results and unwanted side effects being the two biggest reasons why a large number of psoriasis and psoriatic arthritis patients go untreated or abandon conventional treatment, according to this 2013 study that spanned research based on patients interviewed between 2003 and 2011.

The ketones also cause a strong diuretic effect on the kidneys, resulting in losses of large amounts of fluid.

Indeed, my results confirm that a teacher's gender does have large effects on student test performance, teacher perceptions of students, and students» engagement with academic material.

Nor are results much better for attending college: «While the estimated effect of charter attendance on college attendance is positive, it is not large enough to generate a statistically significant finding.»

Results of examining the differential effects of peers from troubled families by race and gender show relatively large negative and statistically significant test - score effects on white boys and statistically insignificant effects on black boys, black girls, and white girls.

In these models, the effects of pay for performance are shown to be even larger than the results based on comparisons across continents.

Our results indicate that while the pilot evaluation system led to large short - term, positive effects on school reading performance, these effects were concentrated in schools that, on average, served higher - achieving and less - disadvantaged students.

Like virtually all prior work, their results suggested that the effect on educational attainment is largest for urban minority students.

And, in fact, the results of this separate experiment confirmed that ECO-C generally had larger effects on our target group than on these other high achievers.

However, in looking at the results for students separated by race and gender, both types of reforms had fairly large and statistically significant effects on the probability of completing high school for some groups.

As is his wont, he ignores the results from a randomized field trial, conducted by Johns Hopkins researchers, that found that Success for All has large, statistically significant positive effects on student literacy.

The cross-country comparative approach provides a number of unique advantages over national studies: It can exploit institutional variation that does not exist within countries; draw on much larger variation than usually available within any country; reveal whether any result is country - specific or more general; test whether effects are systematically heterogeneous in different settings; circumvent selection issues that plague within - country identification by using system - level aggregated measures; and uncover general - equilibrium effects that often elude studies in a single country.

I do this by looking at the sample of students who are continuously enrolled in a district school between grades 3 and 5 in order to exclude students coming from and going to other schools; their results are nearly identical to, if not slightly larger than, the effects on the full sample.

I have written about voucher results from Louisiana extensively before, especially the large negative effects that the state's program, and a similar program in Ohio, have had on the achievement of students using them to move to private schools.

«It would be difficult to see how the range of teacher effects on the 8th grade Reading test would be considered substantively meaningful if this result holds up in a larger and random sample.

Results showed a medium to large effect on students» reading over the course of the four years (effect size = +0.37) compared to the control group.

These results tend to be larger and are more statistically significant than the estimated effects of proximity to a Superfund site on birth outcomes.

Much of Mike's work supports school and district leaders in planning and implementing large - scale improvement initiatives, visioning, understanding change and its effect on people, evaluating school improvement progress, designing exceptional professional development, and engaging people in productive, relationship - rich, results - based conversations.

The Highway Loss Data Institute said it conducted the first large - scale assessment of the effects of anti-lock brakes on motor vehicle crashes and found «disappointing results.»

Press the centre of the back and there's just a little give which you don't get on the larger iPad, and pressing the screen does result in the LCD distorting more readily but neither detract from the overall effect.

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Such statements reflect the current views of Barnes & Noble with respect to future events, the outcome of which is subject to certain risks, including, among others, the effect of the proposed separation of NOOK Media, the general economic environment and consumer spending patterns, decreased consumer demand for Barnes & Noble's products, low growth or declining sales and net income due to various factors, possible disruptions in Barnes & Noble's computer systems, telephone systems or supply chain, possible risks associated with data privacy, information security and intellectual property, possible work stoppages or increases in labor costs, possible increases in shipping rates or interruptions in shipping service, effects of competition, possible risks that inventory in channels of distribution may be larger than able to be sold, possible risks associated with changes in the strategic direction of the device business, including possible reduction in sales of content, accessories and other merchandise and other adverse financial impacts, possible risk that component parts will be rendered obsolete or otherwise not be able to be effectively utilized in devices to be sold, possible risk that financial and operational forecasts and projections are not achieved, possible risk that returns from consumers or channels of distribution may be greater than estimated, the risk that digital sales growth is less than expectations and the risk that it does not exceed the rate of investment spend, higher - than - anticipated store closing or relocation costs, higher interest rates, the performance of Barnes & Noble's online, digital and other initiatives, the success of Barnes & Noble's strategic investments, unanticipated increases in merchandise, component or occupancy costs, unanticipated adverse litigation results or effects, product and component shortages, risks associated with the commercial agreement with Samsung, the potential adverse impact on the Company's businesses resulting from the Company's prior reviews of strategic alternatives and the potential separation of the Company's businesses (including with respect to the timing of the completion thereof), the risk that the transactions with Pearson and Samsung do not achieve the expected benefits for the parties or impose costs on the Company in excess of what the Company anticipates, including the risk that NOOK Media's applications are not commercially successful or that the expected distribution of those applications is not achieved, risks associated with the international expansion previously undertaken, including any risks associated with a reduction of international operations following termination of the Microsoft commercial agreement, the risk that NOOK Media is not able to perform its obligations under the Pearson and Samsung commercial agreements and the consequences thereof, the risks associated with the termination of Microsoft commercial agreement, including potential customer losses, risks associated with the restatement contained in, the delayed filing of, and the material weakness in internal controls described in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, risks associated with the SEC investigation disclosed in the quarterly report on Form 10 - Q for the fiscal quarter ended October 26, 2013, risks associated with the ongoing efforts to rationalize the NOOK business and the expected costs and benefits of such efforts and associated risks and other factors which may be outside of Barnes & Noble's control, including those factors discussed in detail in Item 1A, «Risk Factors,» in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended May 3, 2014, and in Barnes & Noble's other filings made hereafter from time to time with the SEC.