Acupuncture is used successfully for
a large number of conditions including sore backs and necks, lameness, neuropathies (peripheral nerve paralysis), gastrointestinal motility disorders (including ileus and chronic mild colic) and reproductive disorders (including fluid retention and endometritis).
Inflammation plays a large role in many of the symptoms associated with
a large number of conditions (i.e., Lyme disease, CFS, FM, autoimmune diseases, infections, etc.), making the potential impact of Tβ4 quite extensive.
Not exact matches
More favourable growing
conditions this season should lead to a sharp increase in the
number of red and white grapes crushed, while regions such as Swan and Manjimup should continue to see increasingly
larger yields over the next five years.
«Current treatments for depression work for many people but there is still a significant unmet need for a
large number of patients living with this very challenging
condition.»
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a
larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect
of lowering prices or reducing the
number of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market
conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Additionally, the legislation left in place a
large number of legal requirements in the ACA, including the essential benefits package requirements, the prohibition on insurers denying or charging more for coverage for those pre-existing
conditions, the limits on «medical loss ratios,» and other changes that do not have a direct budgetary effect.
In my humble opinion, global financial
conditions in the light
of European instability will play a
larger role in the Fed's decision to raise rates, which is why I maintain it will take a
large number to give voice to those Fed voters wishing to raise rates.
Such a society depends on the willingness
of large numbers of people to undertake tedious and unrewarding work at low pay and in very poor
conditions.
This sentiment did not exclude awareness
of real problems, one
of which is the
condition and status
of large numbers of foreign workers (half
of them illegal) from Indonesia, the Philippines and India.
A great many people are trying to ban forms
of womens» healthcare, and perhaps you are too young to remember, but when it was illegal before,
large numbers of women turned to «back alley» abortions, often performed in unsanitary
conditions by untrained people.
Yet if the Requiem can call
large numbers of people, regardless
of their religious views, to consider just for a second the human
condition and what people have inflicted on one another, then I am truly happy to have «failed.»
Starting with the LARVIVA diets for hatcheries and a
number of specific types
of fry feeds we offer a
large variety
of transfer feeds and grower feeds developed to match the nutritional needs
of specific species in various farming
conditions.
Our side has enjoyed a very impressive season in front
of our home crowd, with much
of our disappointments coming on the road, but with the adverse weather
conditions and warnings, a
large number of supporters will not have been able to make the trip, and we therefore ended up playing out the match in front
of a minimal size crowd.
Moreover, while moratoria on executions should be welcomed, if they are not accompanied by a change in judicial practice, long - term moratoria result in a
large number of people languishing on «death row», a
condition which may amount to cruel, inhuman or degrading treatment.
A source, who spoke to one
of our correspondents on
condition of anonymity, said, «There were coordinated attacks on five communities by the well - armed herdsmen who stormed our villages in
large number, around 10 pm to 4 am.
Peter Goldmark, Washington's commissioner
of public lands, said that beyond the challenge in addressing the
large number of incidents, «it's also the very adversarial weather
conditions that we've found ourselves in.»
«Essentially, they showed me that a
large number of traffic incidents are caused by medical
conditions while driving, specifically cardiovascular events, such as myocardial infraction and myocardial ischemia,» says Najarian, director
of data science at the Michigan Center for Integrative Research in Critical Care.
Researchers also need to test a
large number of battery cells over a long enough period
of time under various physical
conditions and temperatures to ensure that dendrites will never grow.
Laboratory studies suggest that explosive development
of ice crystals can occur in these
conditions, at temperatures between -4 and -8 degrees Celsius, and this «rime - splintering» mechanism is often invoked to explain past observations
of the rapid development
of large numbers of ice crystals in cumuli.
In addition to helping farmers check crop health, the new system will be helpful for studying how plants respond to changes in growing
conditions and for high - throughput phenotyping, an automated method used in crop research and development to analyze how genetic modifications affect plant characteristics such as leaf size or drought resistance in a
large number of plants.
COSEPUP surveyed 25 academic institutions in the U.S. that had the
largest numbers of postdocs, as well as governmental labs and industry, to get a better sense
of postdoctoral employment
conditions.
Gadolinium - based contrast agents have a proven track record for accurate diagnosis and treatment monitoring
of a
large number of diseases including cancer, neurological pathology, heart disease, liver disease, and many other important
conditions afflicting adults and children.
To be able to experimentally verify this «and» state and its unique quantum mechanical properties, the team had to create a
large number of these atomic systems under the same
conditions and with different settings
of the lab setup.
Indeed, under these
conditions an atom belonging to a given sublattice has only a very small
number of neighbors (one or two) in each
of the other sublattices, and the molecular field method, which consists in replacing the instantaneous action
of an atom by that
of an average atom, will be more likely to yield a correct result, the
larger the
number of atoms to which it is applied.
Cooler climatic
conditions and an excess
of rain had led to failed crop harvests and widespread hunger, in addition to
large numbers of people living in crowded — and already pathogen - filled — medieval cities.
In a letter to the chairman
of the investigation, Feynman explained his findings: «The
large number of negative observations are a result
of the appalling
condition the NASA shuttle program has gotten into.»
The
number of hatchlings in the Gulf
of Mexico has increased substantially since the mid-1980s, but it has varied quite a bit in recent years, suggesting that oceanographic
conditions may also be behind this year's
large crop
of stranded turtles.
«However, we hadn't realised there may be a
large number of genes fueling the interactions, or that these types
of genes hamper a species» ability to adapt to new
conditions.»
«We observed that a
large number of genes were involved in pathways related to wound healing, immunity, and metabolism, and this is consistent with the idea that the earliest stages
of domestication may involve adapting to highly crowded
conditions,» said Mark Christie, lead author
of the study.
«The anoxic
conditions have been present in this area for hundreds
of years, but the
large numbers of jellyfish are a recent occurrence, so their tolerance
of their stinging tentacles is presumably a more recent adaptation, as is their use
of jellyfish as a food source,» Braithwaite says.
«We are now at a stage where a
large enough
number of these simulations can be run to map out
large parts
of the phase diagram
of materials under extreme
conditions in sufficient detail to effectively support experimental efforts.»
The
condition was compared to two market
conditions in which either only one buyer and one seller (bilateral market) or a
larger number of buyers and sellers (multilateral market) could trade with each other.
«Our new imagery shows
large variability in the
conditions along the megathrust, which may be linked to a
number of earthquake phenomena we observe in the region,» Edwards said.
«The way most industrial processes are designed today is by doing an exhaustively
large number of experiments to find out how crystals grow and at what rate they grow under different
conditions,» said UCSB chemical engineer Michael Doherty, an author
of a paper that appears in the Proceedings
of the National Academy
of Sciences.
Furthermore the modelling approach is inherently
of no value for predicting future temperature with any calculable certainty because
of the difficulty
of specifying the initial
conditions of a
large number of variables with sufficient precision prior to multiple iterations.
They find that wind delays smaller ants more than
larger ones and that in windy
conditions, colonies increase the
number of larger ants, which are better able to deal with wind.
The accessibility
of a
large numbers of tidewater glaciers, subject to warming
conditions, provides a unique opportunity to observe processes and enable more accurate predictions
of sea level response to ocean warming around Antarctica.
They can be easily frozen and thawed, ensuring production
of a
large number of qualified feeder cells and allowing comparison
of the variables influencing reprogramming efficiency under relatively stable
conditions.
«We have a
larger number of patients in our group than on any single clinical trial, so we hope this will be an opportunity for researchers to learn about us and a way for us to learn more about our
condition.
In the inner solar system, beyond Earth the best example
of this is Venus but thanks to the obsession over the fantastically nasty surface
conditions the exploration
of this fascinating environment has been woefully neglected in favour
of large numbers of missions to the frozen dirtball that is Mars.
The implication is that the current epidemic is the result
of a familiar virus invading a new geographical area where
conditions for it to spread are highly favourable, with high densities
of people who have never been exposed to Zika virus before, and
large numbers of the mosquitoes which transmit the virus.
Whilst a
number of genes have been identified previously from investigation
of families with Mendelian inheritance patterns, sequencing the DNA from
large cohorts
of individuals with congenital heart disease is now providing fresh insights into the genetics
of these
conditions.
That makes it relatively simple to gauge the effectiveness
of large numbers of drug candidates in treating a
condition caused by a particular mutation.
The effect
of the LGR4 mutation on many other
conditions was further investigated taking advantage
of a
large number of human diseases and other traits that are available at deCODE.
The team finds that including more realistic starting
conditions (a
larger number of planetesimals and planetesimals with higher ice content) than usually assumed, red dwarf planets will not be dry.
Sleep is vital to health and lack
of it or a poor sleep quality is associated with a
large number of medical and psychiatric
conditions.
It's hard not to be affected by the entire buzz about the amazing maca root benefits starting from nutrition benefits and ending with
large number of health
conditions that maca might have positive effects on.
Excess consumption
of polyunsaturated oils has been shown to contribute to a
large number of disease
conditions including increased cancer and heart disease; immune system dysfunction; damage to the liver, reproductive organs and lungs; digestive disorders; depressed learning ability; impaired growth; and weight gain.31
SIBO (Small Intestinal Bacterial Overgrowth) is a
condition in which abnormally
large numbers of bacteria — the types that are normally found in the
large intestine — are present in the small intestine.
Effectiveness trials aim to test the intervention under realistic
conditions in a
large number of schools.