Sentences with phrase «large number of mice»

They conducted a very well designed study that included a large number of mice treated with CTEP in two different ways - for a very short time (1 week), or a prolonged window of 3 months.

We conclude that the large number of mouse mutants and human de novo mutations may be due to the combination of the Chd7 gene being a large target and the fact that many heterozygous carriers of the mutations are viable individuals with a readily detectable phenotype.

Not exact matches

This week, the House of Mouse reported favorable attendance numbers at its only theme park on mainland China amid questions about the fallout from a trade war between the world's two largest economies.

I could go on and elaborate on a number of other disciplines or facts that creationists have to pretend into oblivion to retain their faith, including the Ice Ages, cavemen and early hominids, much of microbiology, paleontology and archeology, continental drift and plate tectonics, even large parts of medical research (medical research on monkeys and mice only works because they share a common ancestor with us and therefore our fundamental cell biology and basic body architecture is identical to theirs).

«Indeed, in a second tumor model of metastatic breast cancer, we demonstrated that mice treated with the EphA2 - targeting paclitaxel conjugate presented nearly no lung metastases, while a large numbers of lesions were observed in both untreated mice and in mice treated with just paclitaxel.»

The largest effect was on the number of times the mice went in and out of a sleep phase called paradoxical sleep, which resembles REM (rapid eye movement) sleep in humans, when dreams occur and memories are strengthened.

Running produced a large increase in the number of new neurons in the hippocampus — a brain region shown to regulate anxiety — of a mouse that ran for six weeks (above).

Zelikoff's studies found mice exposed in utero to gutkha had a larger number of cardiovascular risk factors.

The new findings, recently published in Inflammatory Bowel Diseases, revealed increases in the numbers of Proteobacteria, a large phylum [group] of microbes, in the intestines of mice drinking water supplemented with Splenda.

The scientific community uses knockout mice to analyze basal phenotypes (the appearance of genetic characteristics) to analyze the function of such a large number of genes.

This is not easy, however, as it requires a large number of immune cells and a lot of mice need to be bred as donors.

By allowing a large number of ovulation ovum from a small number of female mice, it makes it easier to perform IVF and embryo transfers.

Later, when these mice were weaned onto a solid food diet, large numbers of pTreg cells in the small intestine emerged rapidly within a few weeks.

Twenty - four hours after the injection, the researchers saw large numbers of immune system white blood cells in tissue samples of the rodent brains near the site of injury of those mice injected with the cytokine IL - 1b, but not in the brain tissue of the control group of mice.

«When we compared the gene signature activity of glioblastoma cells from around 60 patients we found that a large number of patients could be divided into subgroups that showed a correlation between gene activity, tumor cell characteristics and cell of origin similar to the one we had seen in the mouse study.

The researchers found that the mice responded to the parasite by shifting their immune system into high gear, producing large numbers of white blood cells.

The mice seem to develop normally when only one copy of the gene is removed, but microscopic inspection reveals a number of small «gaps,» or disorganized regions of tissue (on the scale of a few nanometers) on their aortas, the largest artery in their bodies.

A large number of lab studies using rats and mice exposed to high doses of BPA failed to show measurable effects on key aspects of reproductive development, function and behaviour.

Similarly, we observed that male IL - 15Rα — KO mice produced 6.3-fold more wheel revolutions compared with B1629 control mice in cage wheel running experiments and had a larger number of ambulatory photobeam breaks in the light and dark cycles.

This result implies that only large treatment effects can be detected by efficacy studies in hAPP mice, since the number of mice per group will likely not be greater than 50, for practical and ethical reasons.

This is likely true for two reasons; 1) there would not have been much time for a large number of chromosomal rearrangements to occur between these early ancestral human and mouse genomes, 2) and that since divergence with the boreoeutherian ancestor the human genome has undergone only a small number of chromosomal rearrangements meaning that many human telomeric regions are ancestral [58, 73].

Histopathological examination of rejected corneal allografts in CD4 KO mice revealed a mixed inflammatory infiltrate containing large numbers of neutrophils and mononuclear cells, which was indistinguishable from the infiltrate seen in rejected corneal allografts in wild - type mice (data not shown).

Secondly, the mouse genome is significantly smaller than the human genome, making it possible to detect a large number of lineage - specific deletion events [17, 19].

A very large number of changes have been discovered in HD model mice and then subsequently observed in human HD patients, suggesting the mice are useful research tools, even if they don't really have Huntington's disease.

Researchers have discovered a large - and continually growing - number of ways to significantly extend healthy and maximum life span in mice.

As potential lead drug candidates, we generated a large number of derivatives of the curry spice curcumin, which is effective in AD transgenic mice [8, 9].

But, by focusing on tissue obtained from mouse embryos, the Salk researchers were able for the first time to identify and isolate a sufficiently large number of fetal breast stem cells to begin to understand how their GPS works.

This new mouse model could be very useful in allowing an initial comparative assessment of the likely potential value of the large number of Zika vaccine candidates being developed around the world.

For meaningful scientific interpretation of histopathological data through analysis of large cohorts of mice, we recommend, 24 mice per age group (i.e., number used in systematic clinical tests).

Despite a large number of sex - specific gametogenesis proteins uncovered in the model organisms Drosophila, C. elegans and mice, no conserved male - or female - specific gametogenic factors common to all lineages of animals have been clearly demonstrated [30]--[33].

A series of mouse brain sections is explored for protein expression and distribution in a large number of brain regions.

There are a large number of laboratory strains available, and their long breeding history means that mice of a single laboratory strain are isogenic.

We recently described retinal regeneration in rd10 mice, which is a model of retinitis pigmentosa, a severe disease that affects a large number of individuals and that results in progressive loss of vision (Sanges et al JCI 2010).

The Sanger Institute Gene Trap Resource (SIGTR) mouse ES cell line collection was developed to provide a powerful and cost effective approach using gene trapping to create large numbers of insertional mutations that are immediately accessible to molecular characterization.

And while the human and T cells they studied in the laboratory were not specifically skin T cells they were isolated from mouse cell culture and from human blood — the skin has a large share of T cells in humans, he says, approximately twice the number circulating in the blood.

In the process of exploring how the liver's daily cycles work, Panda found that mice which eat within a set amount of time (12 hours) resulted in slimmer, healthier mice than those who ate the same number of calories in a larger window of time, showing that when one eats may be as important as what one eats.

There are several 28 - toed kitties currently reported to be padding about, but the largest ever verified number of toes was 32, 8 per foot, reported in 1974 on a male cat named «Mickey Mouse» from California.

It's a Rube Goldberg machine that uses an unnecessarily large number of moving parts to catch a mouse.

While the G602 has a hefty helping of extra buttons, it's worth noting that the mouse lacks the larger 12 - button number pads of the Razer Naga and Logitech G600, both of which match the G602's retail value of $ 79.

Faces: There are three new watch faces in watchOS 3: Minnie Mouse (similar to Mickey Mouse face, except the dress is customisable to match Apple Watch bands), Activity (shows a larger view of your daily activity rings at a glance and can be set to an analog clock, a digital clock, or a chronograph), and Numerals (displays a single number with watch hands; the number changes and rotates as time passes).

With sites out there like career builder and monster dot com it is much easier to submit your resume to a large number of employers with the click of a mouse.