Sentences with phrase «large number of mutations»
The scientists also found that children with congenital heart disease carry large numbers of mutations in genes that are active during brain development.
hhmi.org
In cases where there are lots of T cells in the vicinity of a tumor, or where tumor cells have undergone large numbers of mutations, which creates additional targets for immune sentries, T cells will signal a full - fledged immune response to the cancer.
Cancer cells that have a relatively large number of mutations in their DNA express aberrant proteins — or neoantigens — that reveal the cancer to the immune system.
The upper end of the range is above the results previously reported using more complex design approaches26, 27 (iterative design and design based on Rosetta), which also involved large numbers of mutations to reach those efficiencies, and it is less than two orders of magnitude below the catalytic efficiency for the best Kemp eliminase reported for to date28 (which is the outcome of 17 rounds of directed evolution from an iterative design background).
«Interestingly, despite having a large number of mutations, the young patients present with relatively mild neurological problems.»
Even in areas of Barrett's esophagus without cancer, the researchers found a large number of mutations in their tissue — on average 12,000 per person (compared to an average of 18,000 mutations within the cancer).
«Because skin cancers are so common in the population, it makes sense that individuals would carry a large number of mutations.
They suspected his recovery might have to do with the large number of mutations in his tumors.
For this reason, these tumours contain a large number of mutations.
«Thanks to whole - genome sequencing, we were able to identify a larger number of mutations,» he said.
It turns out that the genes connected to OCD in dogs also display a larger number of mutations in humans with an OCD diagnosis.
An internationally renowned expert in the field of gender - based biology, he has identified a large number of mutations in sex - determining genes, developed animal models with atypical sexual development, and identified novel mechanisms of sex differences in the brain.