Most importantly, the collaboration leveraged the expertise of the two groups: Sabeti's team had methods and technologies that enabled them to sequence
a large number of samples in great depth, while CDC was able to provide what Daniel Park, a Broad researcher and the paper's co-first author, described as «some of the cleanest, easiest samples to sequence» his team had ever studied.
The synchronous processing of
a large number of samples in record time and at a reduced cost is not the only advantage of this new tool.
This study, published in the journal Molecular Ecology Resources, presents a revolutionary tool to process a very
large number of samples in parallel, allowing wide coverage of the monitored sites in a reduced time and at a lower cost.
Not exact matches
Now, when you take basic statistics
in college and start to learn the rule
of proper population
samples and the rule
of large numbers, get back to me.
It follows that, if the discrepancy between the
number of possible states and the
number of possible
samples is
large enough, we can assert without fear
of contradiction that no two members
of a class, e.g., no two members
of an animal or plant species, not even two bacteria, can ever be
in the same internal state.
I believe, a good exercise would be to take a sufficiently
large sample size
of players who played for Arsenal and some other club for a long period, say at least 3 - 4 years and compare their injury records
in the two phases (
number, frequency and nature
of injuries incurred).
One
of the first such studies25 linked slapping and spanking
in childhood with psychiatric disorders
in adulthood
in a
large Canadian
sample, and its findings have since been supported by an ever - growing
number of studies.
We looked at the record
of a
number of individual committees — specifically those calling more than 20 witnesses
in this period, providing a
larger sample size.
One method, called intracytoplasmic sperm injection (ICSI), has the potential to allow greater
numbers of offspring to be produced from individual mares and from stallions where sperm
samples are limited, allowing breeds to continue
in larger numbers.
However,
in later studies, researchers evaluating much
larger numbers of virus
samples could not confirm the high rate.
The strength
of the paper, he says, is that the
large number of animals involved provide a good
sample of the different ways
in which chimp brains age.
Tissue engineers have been unable to grow epidermis with the functional barrier needed for drug testing, and have been further limited
in producing an
in vitro (lab) model for
large - scale drug screening by the
number of cells that can be grown from a single skin biopsy
sample.
Yet because
of the difficulty
in collecting
samples from so far below the ocean surface, and because
of the
large area that was impacted by the spill, a
number of gaps
in understanding the fate
of the oil over time remained.
The assay was implemented
in five countries and tested using a
large number of clinical
samples from travelers and patients living
in areas with a high level
of exposure to Zika virus and other flaviviruses.
Researchers from the University
of Leicester's Department
of Cancer Studies and Molecular Medicine,
in collaboration with Cleaver Scientific Ltd., have developed a novel, high throughput method
of performing the assay which is set to overcome this problem and to push down the costs
of processing
large numbers of samples.
By looking at the changes
in healthy food availability
in a
sample of food stores
in the city
of Baltimore between 2006 and 2012, researchers found that corner stores, particularly
in neighborhoods with
large numbers of black residents, were modestly but significantly more likely to carry a
larger number of those healthful choices.
«Tim and I were able to work very closely
in all the steps
of the project from the experimental design
in the wet lab to the final analysis
of the results; the major challenge was how to handle the very
large number of barley
samples and for this we designed a novel approach to sequencing that exploited deep results
in combinatorics,» Lonardi said.
Twenty - four hours after the injection, the researchers saw
large numbers of immune system white blood cells
in tissue
samples of the rodent brains near the site
of injury
of those mice injected with the cytokine IL - 1b, but not
in the brain tissue
of the control group
of mice.
Cahill has led some
of the most exhaustive scientific studies
of 9 / 11 - related toxins, and he has discovered a
large number of health - threatening substances from air
samples taken
in the weeks and months after 9/11.
With its
large sample size, this study had the power to find copy
number variants with
large effects that occur
in more than 0.1 percent
of schizophrenia cases.
The authors caution that their study was conducted
in a country with strong social welfare supports and that while the
sample overall was
large, the
number of children with many symptoms
of ADHD was relatively small.
Although none
of the German Neolithic
samples carries the copy
number expansion
of the AMY2B gene associated with starch digestion, we find that this gene is present
in three copies
in NGD, though this is due to a
large segmental duplication that is shared with multiple modern dogs, an event separate from the tandem AMY2B duplications.
Finally, some researchers worry that even though these registries are supposed to reduce the
number of animals
in biomedical research, their labs may end up using more animals because they feel they need
larger sample sizes to conduct more robust research as part
of these registries.
g (acceleration due to gravity) G (gravitational constant) G star G1.9 +0.3 gabbro Gabor, Dennis (1900 — 1979) Gabriel's Horn Gacrux (Gamma Crucis) gadolinium Gagarin, Yuri Alexeyevich (1934 — 1968) Gagarin Cosmonaut Training Center GAIA Gaia Hypothesis galactic anticenter galactic bulge galactic center Galactic Club galactic coordinates galactic disk galactic empire galactic equator galactic habitable zone galactic halo galactic magnetic field galactic noise galactic plane galactic rotation galactose Galatea GALAXIES galaxy galaxy cannibalism galaxy classification galaxy formation galaxy interaction galaxy merger Galaxy, The Galaxy satellite series Gale Crater Galen (c. AD 129 — c. 216) galena GALEX (Galaxy Evolution Explorer) Galilean satellites Galilean telescope Galileo (Galilei, Galileo)(1564 — 1642) Galileo (spacecraft) Galileo Europa Mission (GEM) Galileo satellite navigation system gall gall bladder Galle, Johann Gottfried (1812 — 1910) gallic acid gallium gallon gallstone Galois, Évariste (1811 — 1832) Galois theory Galton, Francis (1822 — 1911) Galvani, Luigi (1737 — 1798) galvanizing galvanometer game game theory GAMES AND PUZZLES gamete gametophyte Gamma (Soviet orbiting telescope) Gamma Cassiopeiae Gamma Cassiopeiae star gamma function gamma globulin gamma rays Gamma Velorum gamma - ray burst gamma - ray satellites Gamow, George (1904 — 1968) ganglion gangrene Ganswindt, Hermann (1856 — 1934) Ganymede «garbage theory»,
of the origin
of life Gardner, Martin (1914 — 2010) Garneau, Marc (1949 ---RRB- garnet Garnet Star (Mu Cephei) Garnet Star Nebula (IC 1396) garnierite Garriott, Owen K. (1930 ---RRB- Garuda gas gas chromatography gas constant gas giant gas laws gas - bounded nebula gaseous nebula gaseous propellant gaseous - propellant rocket engine gasoline Gaspra (minor planet 951) Gassendi, Pierre (1592 — 1655) gastric juice gastrin gastrocnemius gastroenteritis gastrointestinal tract gastropod gastrulation Gatewood, George D. (1940 ---RRB- Gauer - Henry reflex gauge boson gauge theory gauss (unit) Gauss, Carl Friedrich (1777 — 1855) Gaussian distribution Gay - Lussac, Joseph Louis (1778 — 1850) GCOM (Global Change Observing Mission) Geber (c. 720 — 815) gegenschein Geiger, Hans Wilhelm (1882 — 1945) Geiger - Müller counter Giessler tube gel gelatin Gelfond's theorem Gell - Mann, Murray (1929 ---RRB- GEM «gemination,»
of martian canals Geminga Gemini (constellation) Gemini Observatory Gemini Project Gemini - Titan II gemstone gene gene expression gene mapping gene pool gene therapy gene transfer General Catalogue
of Variable Stars (GCVS) general precession general theory
of relativity generation ship generator Genesis (inflatable orbiting module) Genesis (
sample return probe) genetic code genetic counseling genetic disorder genetic drift genetic engineering genetic marker genetic material genetic pool genetic recombination genetics GENETICS AND HEREDITY Geneva Extrasolar Planet Search Program genome genome, interstellar transmission
of genotype gentian violet genus geoboard geode geodesic geodesy geodesy satellites geodetic precession Geographos (minor planet 1620) geography GEOGRAPHY Geo - IK geologic time geology GEOLOGY AND PLANETARY SCIENCE geomagnetic field geomagnetic storm geometric mean geometric sequence geometry GEOMETRY geometry puzzles geophysics GEOS (Geodetic Earth Orbiting Satellite) Geosat geostationary orbit geosynchronous orbit geosynchronous / geostationary transfer orbit (GTO) geosyncline Geotail (satellite) geotropism germ germ cells Germain, Sophie (1776 — 1831) German Rocket Society germanium germination Gesner, Konrad von (1516 — 1565) gestation Get Off the Earth puzzle Gettier problem geyser g - force GFO (Geosat Follow - On) GFZ - 1 (GeoForschungsZentrum) ghost crater Ghost Head Nebula (NGC 2080) ghost image Ghost
of Jupiter (NGC 3242) Giacconi, Riccardo (1931 ---RRB- Giacobini - Zinner, Comet (Comet 21P /) Giaever, Ivar (1929 ---RRB- giant branch Giant Magellan Telescope giant molecular cloud giant planet giant star Giant's Causeway Giauque, William Francis (1895 — 1982) gibberellins Gibbs, Josiah Willard (1839 — 1903) Gibbs free energy Gibson, Edward G. (1936 ---RRB- Gilbert, William (1544 — 1603) gilbert (unit) Gilbreath's conjecture gilding gill gill (unit) Gilruth, Robert R. (1913 — 2000) gilsonite gimbal Ginga ginkgo Giotto (ESA Halley probe) GIRD (Gruppa Isutcheniya Reaktivnovo Dvisheniya) girder glacial drift glacial groove glacier gland Glaser, Donald Arthur (1926 — 2013) Glashow, Sheldon (1932 ---RRB- glass GLAST (Gamma - ray
Large Area Space Telescope) Glauber, Johann Rudolf (1607 — 1670) glaucoma glauconite Glenn, John Herschel, Jr. (1921 ---RRB- Glenn Research Center Glennan, T (homas) Keith (1905 — 1995) glenoid cavity glia glial cell glider Gliese 229B Gliese 581 Gliese 67 (HD 10307, HIP 7918) Gliese 710 (HD 168442, HIP 89825) Gliese 86 Gliese 876 Gliese Catalogue glioma glissette glitch Global Astrometric Interferometer for Astrophysics (GAIA) Global Oscillation Network Group (GONG) Globalstar globe Globigerina globular cluster globular proteins globule globulin globus pallidus GLOMR (Global Low Orbiting Message Relay) GLONASS (Global Navigation Satellite System) glossopharyngeal nerve Gloster E. 28/39 glottis glow - worm glucagon glucocorticoid glucose glucoside gluon Glushko, Valentin Petrovitch (1908 — 1989) glutamic acid glutamine gluten gluteus maximus glycerol glycine glycogen glycol glycolysis glycoprotein glycosidic bond glycosuria glyoxysome GMS (Geosynchronous Meteorological Satellite) GMT (Greenwich Mean Time) Gnathostomata gneiss Go Go, No - go goblet cell GOCE (Gravity field and steady - state Ocean Circulation Explorer) God Goddard, Robert Hutchings (1882 — 1945) Goddard Institute for Space Studies Goddard Space Flight Center Gödel, Kurt (1906 — 1978) Gödel universe Godwin, Francis (1562 — 1633) GOES (Geostationary Operational Environmental Satellite) goethite goiter gold Gold, Thomas (1920 — 2004) Goldbach conjecture golden ratio (phi) Goldin, Daniel Saul (1940 ---RRB- gold - leaf electroscope Goldstone Tracking Facility Golgi, Camillo (1844 — 1926) Golgi apparatus Golomb, Solomon W. (1932 — 2016) golygon GOMS (Geostationary Operational Meteorological Satellite) gonad gonadotrophin - releasing hormone gonadotrophins Gondwanaland Gonets goniatite goniometer gonorrhea Goodricke, John (1764 — 1786) googol Gordian Knot Gordon, Richard Francis, Jr. (1929 — 2017) Gore, John Ellard (1845 — 1910) gorge gorilla Gorizont Gott loop Goudsmit, Samuel Abraham (1902 — 1978) Gould, Benjamin Apthorp (1824 — 1896) Gould, Stephen Jay (1941 — 2002) Gould Belt gout governor GPS (Global Positioning System) Graaf, Regnier de (1641 — 1673) Graafian follicle GRAB graben GRACE (Gravity Recovery and Climate Experiment) graceful graph gradient Graham, Ronald (1935 ---RRB- Graham, Thomas (1805 — 1869) Graham's law
of diffusion Graham's
number GRAIL (Gravity Recovery and Interior Laboratory) grain (cereal) grain (unit) gram gram - atom Gramme, Zénobe Théophile (1826 — 1901) gramophone Gram's stain Gran Telescopio Canarias (GTC) Granat Grand Tour grand unified theory (GUT) Grandfather Paradox Granit, Ragnar Arthur (1900 — 1991) granite granulation granule granulocyte graph graph theory graphene graphite GRAPHS AND GRAPH THEORY graptolite grass grassland gravel graveyard orbit gravimeter gravimetric analysis Gravitational Biology Facility gravitational collapse gravitational constant (G) gravitational instability gravitational lens gravitational life gravitational lock gravitational microlensing GRAVITATIONAL PHYSICS gravitational slingshot effect gravitational waves graviton gravity gravity gradient gravity gradient stabilization Gravity Probe A Gravity Probe B gravity - assist gray (Gy) gray goo gray matter grazing - incidence telescope Great Annihilator Great Attractor great circle Great Comets Great Hercules Cluster (M13, NGC 6205) Great Monad Great Observatories Great Red Spot Great Rift (
in Milky Way) Great Rift Valley Great Square
of Pegasus Great Wall greater omentum greatest elongation Green, George (1793 — 1841) Green, Nathaniel E. Green, Thomas Hill (1836 — 1882) green algae Green Bank Green Bank conference (1961) Green Bank Telescope green flash greenhouse effect greenhouse gases Green's theorem Greg, Percy (1836 — 1889) Gregorian calendar Grelling's paradox Griffith, George (1857 — 1906) Griffith Observatory Grignard, François Auguste Victor (1871 — 1935) Grignard reagent grike Grimaldi, Francesco Maria (1618 — 1663) Grissom, Virgil (1926 — 1967) grit gritstone Groom Lake Groombridge 34 Groombridge Catalogue gross ground, electrical ground state ground - track group group theory GROUPS AND GROUP THEORY growing season growth growth hormone growth hormone - releasing hormone growth plate Grudge, Project Gruithuisen, Franz von Paula (1774 — 1852) Grus (constellation) Grus Quartet (NGC 7552, NGC 7582, NGC 7590, and NGC 7599) GSLV (Geosynchronous Satellite Launch Vehicle) g - suit G - type asteroid Guericke, Otto von (1602 — 1686) guanine Guiana Space Centre guidance, inertial Guide Star Catalog (GSC) guided missile guided missiles, postwar development Guillaume, Charles Édouard (1861 — 1938) Gulf Stream (ocean current) Gulfstream (jet plane) Gullstrand, Allvar (1862 — 1930) gum Gum Nebula gun metal gunpowder Gurwin Gusev Crater gut Gutenberg, Johann (c. 1400 — 1468) Guy, Richard Kenneth (1916 ---RRB- guyot Guzman Prize gymnosperm gynecology gynoecium gypsum gyrocompass gyrofrequency gyropilot gyroscope gyrostabilizer Gyulbudagian's Nebula (HH215)
The objective
of this study is to validate the diagnostic performance and practical feasibility
of massively parallel genomic sequencing for the non-invasive prenatal assessment
of trisomy 21
in a
large number of pregnancies that have undergone conventional screening and were clinically indicated for definitive testing by amniocentesis or chorionic villus
sampling.
Yet the only way we'll make progress is to study them
in large cohorts
numbering thousands
of samples.
The
large number of DNA
samples brought together
in this study may enable the researchers to detect genes whose individual effects
in the disorder may be small but may still play a role.
As outlined below, we used a microfluidic quantitative PCR (qPCR) system to elucidate the gene expression profiles
of individual human oocytes and small
numbers of cumulus cells using a combination
of a
large number of samples and targets [12], and then extended our studies via the use
of parthenogenesis,
in conjunction with gene expression profiling, as a functional assay
of cytoplasmic maturation
of oocytes.
I like this study because it demonstrates the importance
of looking at both common and rare variants,
in a
large number of samples, to more comprehensively interrogate the genome for complex disease loci.
However, the turnaround time for
larger projects will be based on the
number of samples and the queue
in the laboratory.
These analyses resulted
in an
in - depth characterization
of the CSF proteome and the combined results
of abundant protein and less abundant protein fractions allowed the creation
of an AMT tag database [19] for high - throughput analysis
of a
larger number of individual subject
samples using LC - MS.
Running as facility
of this size requires a massive amount
of support and we work closely with the library preparation team that supplies
large numbers of DNA templates
in a from ready to be sequenced, the Institute's IT team that maintains the extensive amount
of compute and storage infrastructure necessary, sequencing informatics which develops software tools to process, analyse, store and track all the data, projects and
samples for the Illumina pipeline and the development team which invents novel and improved protocols to take better advantage
of this new technology.
For the first time, customers can analyze
large sample numbers at reasonable cost
in short time with ultra-broad coverage
of lipids absolutely quantified to develop new products
in medical, nutritional and cosmetics markets.
«
In our
sample, I expected to see a
large number of negative tweets based on traditional news coverage
of the topic and because HPV can be portrayed as controversial because it brings together the fields
of sexually transmitted infections, immunizations and cancer prevention,» said study co-author Philip Massey.
«The sophisticated gene analysis that led to this finding was only possible because
of the
large number of ALS
samples available,» said ALS Association chief scientist Lucie Bruijn, PhD,
in a press release.
In general, survey results based on
larger numbers of observations are more precise, that is, less prone to
sampling variance than those made across groups with fewer
numbers of observations.
Activities to help learners
of secondary mathematics to interpret frequency graphs, cumulative frequency graphs and box and whisker plots for
large samples and to see how a
large number of data points can result
in the graph being approximated by a continuous distribution.
In the study's
sample of students used to measure effects, the
number of students that used a voucher for one year is ten times
larger than the
number that used a voucher for four years (Appendix Table 1).
In general, survey responses based on
larger numbers of observations are more precise, that is, less prone to
sampling variance, than those made across groups with fewer
numbers of observations.
To obtain a score the
number of your learners responding must represent a sufficiently
large sample of all the
in - scope learners
in your organisation during the survey period.
In truth, the use of commas in the tests was made clear when the sample tests were published in July 2015 where all large numbers included comma
In truth, the use
of commas
in the tests was made clear when the sample tests were published in July 2015 where all large numbers included comma
in the tests was made clear when the
sample tests were published
in July 2015 where all large numbers included comma
in July 2015 where all
large numbers included commas.
Let's look at a
sample composed
of elementary schools that are
larger than the median charter elementary enrollment, and where the foster youth population is higher than 2.26 % (The reason I chose those
numbers is
in footnotes) ¹.
(2) From the group
of borrowers identified under paragraph (d)(1)
of this section, the data manager identifies a
sample that is
large enough to derive an estimate, acceptable at a 95 percent confidence level with a plus or minus 5 percent confidence interval, for use
in determining the
number of borrowers who should be excluded from the calculation
of the program cohort default rate due to improper loan servicing or collection.
You keep repeating that a
sample size
of 100 is small etc etc, but there is a very famous theorem
in statistics called «Law
of large numbers» that actually will disagree with you.
Thorp, the quantitative investor, valued securities on a probabilistic basis and relied on the statistical phenomenon known as «the law
of large numbers» — the law states that more observations we make, the closer our
sample will be to the population, and hence greater the certainty
of our prediction — to construct portfolios
of securities that would,
in aggregate, outperform the market.
Metabolomics is an emerging field
in which a very
large number of small chemicals can be analyzed from
samples of body fluids and tissues.
So far this mutation has been detected
in this breed only, with an estimated carrier frequency
of 25 % based on a
large number of samples collected form dogs originated from Finland, Sweden, United Kingdom and United States.
Further complicating the use
of these proxies is the fact that the deviation
in oxygen - 18 ratios is affected by the amount
of TC rainfall, the distance from the center
of the cyclone at which the rain was produced, and the intensity
of the cyclone — so I doubt these proxies alone will enable disentangling intensity and rainfall, tnough a
large number of samples over an area could reveal information about the track and extent
of the TC event.
Hence, it possible for a
large number of measurements at different locations to result
in a meaningful reduction
in the level
of error
of a quantity, provided that the value
of the quantity does not vary much across the
sample space.
The PDF has been computed
in the same way (apart from the reciprocal relationship) as the climate sensitivity PDF
in Figure 2
in the original paper, using the same data and error distribution assumptions but with a
larger number of random
samples to improve accuracy.