Sentences with phrase «large number of treatment»

Not exact matches

As I've said, there have been a number of research papers of late, led in large part by the work of French scientist Laurence Zitvogel, that are building a strong case for a central role for the microbiome in cancer treatment response.

A number of outfits who say it will expedite the availability of treatments for unmet medical needs, including the largest cancer physician group in the U.S., hailed its passage on Wednesday.

These figures are as large as they are partly because 60 % of sufferers don't comply with their medication or treatment regimen — for any number of reasons including cost, stress, work patterns or lack of education about how to self - manage the disease.

A small number of large video companies such as Netflix, Hulu and YouTube have the massive reach and capital to pay additional fees for preferential treatment to speed video content delivery to end - users.

«Current treatments for depression work for many people but there is still a significant unmet need for a large number of patients living with this very challenging condition.»

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

We operate the largest number of hazardous waste incinerators, landfills, wastewater and other treatment facilities, and treatment, storage and disposal facilities in North America.

In Southern California, a number of water utilities have begun to install large batteries alongside their pumping plants and water treatment facilities.

Although Lu - PSMA - 617 put up good numbers in its small single - arm study, it still needs to outperform a physician's choice of approved treatments in a much larger global trial.

Early and aggressive marketing of a sexually active lifestyle, free birth control and a four times per year purchasing pattern are the Planned Parenthood funnel, out of which comes a large and growing number of big - ticket sales - infection treatment and abortions - for which Planned Parenthood works very hard.

Even if one agrees that synonyms may exist in a natural language (and I don't), this casual treatment of such a large number of terms is unfortunate.

«We know that it takes a large number of bacteria to ultimately produce an infection, and antibacterial treatments can greatly reduce their number» said David Bearden, a clinical associate professor at OSU.

A large number of ovaries increases the chance of pregnancy, but unfortunately has also been associated with ovarian hyperstimulation syndrome (OHSS), which is sometimes called the most important side effect of fertility treatment.

In the last 10 years, a large number of twin and multiple births are attributed to fertility treatments including fertility drugs and in vitro fertilization.

Unlike large residential treatment facilities or psychiatric hospitals, group homes serve a small number of teens.

The only outcome categorised as «high quality» is that treatment for GD reduces the chance of having a baby 4 kg + (number needed to treat NNT = 11.4 to prevent 1 large baby).

Los Angeles has a large number of fertility clinics available to provide these treatments, called In Vitro Fertilization.

Moreover, while moratoria on executions should be welcomed, if they are not accompanied by a change in judicial practice, long - term moratoria result in a large number of people languishing on «death row», a condition which may amount to cruel, inhuman or degrading treatment.

This month's referral to treatment times in Wales have shown a large increase in the number of patients waiting over 9 months to start a course of treatment.

The Welsh Liberal Democrats have questioned Labour's ability to deliver on their new mental health targets, as new figures show a large increase in the number of young people waiting over the target time for specialist treatment.

«This study demonstrates the value of using the SEER database to analyze factors associated with surgery as a treatment for localized pancreatic cancer in a large number of patients over a prolonged period of time,» says Dr. Kim, who is also Chief Medical Officer of UH Seidman Cancer Center and the Charles Hubay Professor at Case Western Reserve School of Medicine.

Very large numbers of eggs (28 - 33) were retrieved and they underwent many more rounds of treatment (up to 10) with fertility drugs than is common practice.

Although changes in treatment methodology still have to be studied, Dr. Cripe believes it may be that the timing of various treatments is what matters, and that perhaps initially suppressing immunity could allow the virus to infect a large number of tumor cells before relieving the immunosuppression to allow the body's own T cells to fight off the tumor.

In Suwa in Nagano Prefecture, a treatment plant near a large number of precision equipment manufacturers reportedly collected nearly 2 kilograms of gold in every metric ton of ash left from burning sludge, making it more gold - rich than the ore in many mines.

«I anticipate a large number of follow - up studies searching for causes and the best treatment option for this newly identified morbidity associated with carotid narrowing.»

«This interesting study looking at maternal ethnicity provides useful data based on a large number of women undergoing fertility treatment.

Gadolinium - based contrast agents have a proven track record for accurate diagnosis and treatment monitoring of a large number of diseases including cancer, neurological pathology, heart disease, liver disease, and many other important conditions afflicting adults and children.

«Roughly one - third of DSM - 5 mild cases would not receive a diagnosis per the ICD - 10 clinical version, which in turn translates to reduced access to treatment services for a fairly large number of individuals,» he said.

There are a number of water - purification technologies on the market today, although many come with drawbacks: Systems that rely on chlorine treatment work well at large scales, but are expensive.

Analyzing large numbers of cells, each with slight differences in their DNA, for their ability to carry out a behavior or survive a drug treatment can reveal the importance of particular genes, or sections of genes, in those abilities.

«Our findings suggest that e-learning can provide an efficient and scalable approach to training large numbers of clinicians in new evidence - based treatments,» said Dr. Bradley D. Stein, the study's lead author, a practicing psychiatrist and a senior scientist at RAND, a nonprofit research organization.

Staffing: Large numbers of staff are needed to care for an individual patient due to the intensity of treatment, the extended need for personal protective equipment, and the necessity to limit work shifts in the patient room to 2 - 4 hours to combat physical and mental fatigue.

This means that hospital - level statistics that include large numbers of infants who did not get active treatment may not be helpful when counseling families about the benefits or burdens of treatment.

Unfortunately, laser treatment has a number of significant drawbacks including a high recurrence rate, laser injury to the retina, and an inability to treat the majority of patients affected with neovascular membranes (because the lesions are too large or ill - defined when discovered).

It also excitingly demonstrates the potential for treatment of a large number of other diseases for which existing therapies are either unsatisfactory or unavailable.»

In research published today in Cell Reports, the team identify a large number of genes that could serve as potential targets for anti-AML treatments and describe how inhibition of one of these genes, KAT2A, destroys AML cells without harming non-leukaemic blood cells.

«Our analysis suggests treatment of the retina with a large number of very small laser burns could prevent this «domino - like» progressive loss of small retinal blood vessels and prevent elevation of VEGF and the major complications of diabetic retinopathy,» Gast said.

This result implies that only large treatment effects can be detected by efficacy studies in hAPP mice, since the number of mice per group will likely not be greater than 50, for practical and ethical reasons.

The research demonstrates a faster, more reliable way to identify large numbers of antigens, the targets of the immune response, which could speed the discovery of disease treatments.

Using good quality data from a large number of people, the experienced scientists conducting this research found that people who took certain types of arthritis drugs had a lower risk of dementia than people not taking this treatment.

In the first trial (Neurology 2007; 68:51 — 55), 12 weeks of phenylbutyrate treatment produced no beneficial effects, although the small number and relatively large age range of the patients may have hidden a modest effect.

As long - term iPSC expansion can give rise to huge amounts of NK cells which are not HLA - restricted, they can serve as an allogenic treatment, this option may allow the treatment of large numbers of patients over a prolonged period of time of required.

Most published studies entailed small number of subjects; well - designed studies with larger sample sizes are needed to ascertain how this test can reduce clinical diagnostic uncertainty or impact treatment planning.

In a pilot study, these investigators examined the safety and feasibility of the protocol in a large number of patients from different institutions, and identified predictors of the clinical response to the treatment.

«This grant enables us to bring our bench - to - bedside treatment program to larger numbers of people recovering from right brain stroke, and produce systematic information supporting its impact,» said A.M. Barrett, MD, director of Stroke Rehabilitation Research at Kessler Foundation.

'' Eric has organized several yearly seminars on the diagnosis and treatment of adrenal fatigue in New Zealand for a large number of health professionals.

Not all summits are noteworthy, but a large number of them provide valuable resources to learn about health and recovery — resources typically unavailable to the busy, overwhelmed, and suffering chronic illness patient whose doctor doesn't keep up with research and new treatment protocols.

You will often find that successful candida treatment can cause in many cases, but certainly not all cases, the rapid death of large numbers of yeast organisms, during which time great amounts of toxins are released from the dead candida microorganisms.

Before the new findings may find their way into treatment, they need to be backed up in a clinical trial with larger numbers of patients and MRI as the endpoint.

They didn't have any knowledge of nutrition, they weren't able to eat nutritious, calorie dense food whenever they wanted due to the absence of agriculture, and their immune systems were likely weaker than ours (living together in large numbers placed enormous selective pressure on our early agricultural ancestors to develop strong immune systems, keep in mind that early human civilizations did not have indoor plumbing... so they were sometimes exposed to fecal matter both from fellow humans and from livestock and they didn't have the kinds of disinfectants and anti-biotics we have today,) so for them to have serious health complications makes perfect sense, nature can be very harsh and doesn't care how long its been since your last meal or what your calorie and micro nutrient needs are... a lot of people died at very young ages back then simply because they got sick and didn't have proper medical treatment or due to malnutrition or starvation.