Sentences with phrase «large numbers involved»

Despite the large numbers involved, Bitcoin's latest downturn is, in fact, milder than those seen both this year and further back, when corrections up to 45 percent were fairly common.

Sarah continues, «The comparative element of the tool makes it easy to digest the large numbers involved in the decrease in travel time over the years.

The odds of the finely tuned universe we live in coming about by chance are so unlikely that it's difficult to conceive of the astronomically large numbers involved.

A surprisingly large number involve goalies who played at international level...

Not exact matches

As Fusion notes, «the nootropics community is surprisingly large and involved,» with a number of online forums offering recipes and information on users» drugs of choice.

Thanks largely to the app revolution that took the smartphone world by storm, software developers (and to a larger extent, IT companies) are getting involved in a number of interesting ways.

«The large number of database query incidents, which involve previously collected communications, confirms long - standing suspicions that the NSA's vast data banks — with code names such as MARINA, PINWALE and XKEYSCORE — house a considerable volume of information about Americans.»

«Glubz» said they believe that as many as «20 +» people subsequently «got involved» (a far larger number than that given by «Vamp»).

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Creating a new platform out of your product involves attracting a large number of users, but our research suggests that user growth isn't linear.

WordStream is a provider of PPC management software and SEO tools for continuously optimizing and expanding Internet marketing efforts, involving large numbers of keywords, such as long tail keywords and search engine keywords.

In this respect, the approach proposed by the Jenkins Panel of separating from the National Research Council a number of its existing technology institutes into a constellation of large - scale, sectoral, collaborative R&D centres involving business, the university sector and the provinces is an important proposal.

Crowdfunding involves raising funds to run a business from a large number of people.

Evidently we have been able to bring in a large number of ideas and proposals, because each of us has been involved, often for a long time, in the action process.

However improbable in a mechanistic sense the elaborate organic structure created by life may appear, it seems increasingly evident that the cosmic substance is drawn toward these states of extreme arrangement by a particular kind of attraction which compels it, by the play of large numbers in which it is involved, to miss no opportunity of becoming more complex and thus achieving a higher degree of freedom.

I do not mean that a happening must involve large numbers to be a crowd event.

Indeed, many of them do and that large proportions are currently involved in such a relationship and that a substantial number of those couples have been together 10 or more years.

As a rule, this happened under the cloak of fighting the partisans [in Soviet territories], yet those who were directly or indirectly involved could scarcely fail to see that the SS brigades and Einsatzgruppen were carrying out a comprehensive «ethnic cleansing,» to which the Wehrmacht, if only by condemning large numbers of Russians to starvation, were giving active support.»

While per capita costs of mass - produced items are low, because of the large numbers of people involved, the cost per issue or per program is normally high.

Introspective self - consciousness involves causal objectification by the dominant occasion of some of the unimaginably large number of concreta making up the human mind / brain, including what can be called the subordinate nonconscious living persons responsible for our habitual behavior, that is, sub-personalities (RHNB 148f).

Also involved is the highly technical discipline of interpreting and revising Whitehead's very sophisticated and rigorous metaphysics, an endeavor which was undertaken in a major way only after 1950 but since then has been carried on by an increasingly large number of both secular philosophers and Christian theologians.

But famine, like a plague, spreads, and, «In reality it's a very large food security crisis involving a number of countries and millions at risk,» said Golden, referring to the crisis situation in vast regions of east Africa.

The large number of people who are involved in small groups, the depth of their involvement, the extent of their caring for each other, and even the degree to which they reach out to others in the wider community all suggest that the social fabric has not unraveled nearly to the extent that many critics have suggested.

He helps show that a variety of forms of imagination is required to bridge the chasm opened up by Plato between the sensible and the intelligible, a bridging that must take into account a large number of fundamental polar contrasts involved in the contrast of physical - mental?

The stability of the crystal of elemental iodine is due to an analagous balance, but one involving a larger number of factors.

The question of providing spiritual fellowship to those committed to Christ in different religious communities is a peculiarly Indian ecclesiological problem which has been with us for many decades and needs to be faced squarely, for the number involved is large and the stand of many of them based on the distinction between the spiritual fellowship of faith and the Christian communality, have theological justification.

Incidentally instead of being killed themselves, the Jews were permitted to slaughter a large number who were involved in the plot against them.

Mr Sims said it was the regulator's biggest merger investigation this year, involving a large number of submissions from motoring organisations, competitors and consumers.

Throughout our website, we strive to provide you with health benefit information that is based on human studies involving large numbers of people who consume foods in an everyday way.

The size of the stadiums involved must also be taken in to account with these numbers, as sides such as the Gunners and the Red Devils are able to fit in far more supporters with their larger grounds.

The large number of athletes involved indicates the discounts were no secret among the students.

In addition, SportsInsights» researchers have shown that «anti-public» sports investing systems can be aided by keying in on games with a lot of public interest (such as games involving nationally - ranked teams, nationally - televised games, big rivalries or popular teams, or games with a large number of bets).

And though NASCAR touts the number of large corporations involved in the sport in some capacity, the reality is these companies are not spending anywhere close to what was being invested during the sport's zenith.

While he was praised highly for some of his shrewd purchases of players, it isn't until you really delve through the Villa ranks and discover who is no longer involved in first - team affairs that you unravel where the whole Randy Lerner (Aston Villa owner) Martin O'Neill relationship really went wrong, with the club's acquisitions of several talented individuals not enough to overshadow the large number of flops which entered Villa Park via O'Neill's say - so, nor did it help balance the books.

I would suggest you read http://www.ahrq.gov/Clinic/tp/brfouttp.htm"rel = «nofollow» > Breastfeeding and Maternal and Infant Health Outcomes in Developed Countries, which is a metaanalysis of a large number of studies involving breastfeeding and formula feeding in developed countries.

I thought it was a lot of fun, but more importantly, it got a large number of people involved in something related to adoption during November.

So all those whimsical pictures completely ignore the large number of animal infant deaths... Anyone, actually involved in rural life, especially in livestock management, is fully aware of this, not least because they often have to intervene to improve the survival rates of these already developed mammalian offspring.

School Bus Safety School bus safety involves the cooperation of a large number of people: the bus driver; each rider; pedestrians and bikers who move in and around the bus, and other drivers.

There are a surprisingly large number of accidents involving kids and high chairs.

Preparing for their communications strategy probably involved examining contingencies, arranging responses to a large number of possibilities and making sure the process of broadcasting on so many different channels was prepared.

Moreover, the British government is involved in a large number of international organizations that share «best practice» for how markets should be regulated, how different regulations interact, and how much it costs to do business across different regulatory jurisdictions.

That is not «movement politics» however - rather the reverse, a low level of engagement from a large number of people, with very little activism involved even from the candidates.

Positions are chosen and policies are made through a process involving a very large number of people, from the individual voters on up to representatives, senators, party elites, and eventually the presidential candidates.

According to another labor source involved in these talks, a number of the largest and most significant unions — including 1199 SEIU, HTC, the laborers, RWDSU, and the UFT — were prepared to call it quits with the WFP, knowing that their withdrawal could very well lead to the party's «collapse.»

She said that since she decided to run, she has received a large number of calls from parents with older children «that are alarmed who have a child involved or a friend of a child and they're begging for somebody to take a stand and say something.»

A large number of genes involved in nervous system development and function were also deregulated.

Such farming involves large fields and / or numbers of animals, large resource inputs (pesticides, fertilizers, etc.), and a high level of mechanization.

One of the team's new biosensors is made from a nanoplasmonic material that is able to accommodate a large number of cells on a single substrate and to monitor cell proliferation, a fundamental process involving cell growth and division, in real time.

«If we find that lymphoscintigrams using tilmanocept are at least as good as the conventional radiocolloid tracer in identification and visualization of sentinel nodes, we would like to see a randomised clinical trial involving large numbers of patients,» says Prof de Bree.

My artistic nephew is making a lamp which involves using the largest possible number of regular tetrahedra — solid bodies with four faces, each an equilateral triangle — whose faces will be painted with various colours.