Sentences with phrase «large numbers of stem cells»

«Our group pioneered the development of cell culture technology for harvesting large numbers of stem cells from human bone marrow and human umbilical cord blood,» Dr. Yeh said, noting that stem cells from these two sources are abundant and can be guided into different types of cells using tissue engineering.

One possibility is that a large number of stem cells populate the skin.

In order to collect a large number of stem cells, the bone marrow is stimulated to mobilize the stem cells from inside the bone marrow out into the blood stream where it is easily accessible.

By collecting and banking your stem cells — especially while you are healthy — you are collecting a large number of stem cells and an array of differentiated cell lines, including the ones committed to form immune cells.

Not exact matches

The new method, described in the journal Stem Cells Translational Medicine, could be used to generate large numbers of muscle cells and muscle progenitors directly from human pluripotent stem ceStem Cells Translational Medicine, could be used to generate large numbers of muscle cells and muscle progenitors directly from human pluripotent stem cCells Translational Medicine, could be used to generate large numbers of muscle cells and muscle progenitors directly from human pluripotent stem ccells and muscle progenitors directly from human pluripotent stem cestem cellscells.

«We have just allocated $ 271 million in funds, which leveraged over $ 500 million from donors and the institutions» own reserves to build 12 stem cell institutes in California; these are really large institutes that will accommodate a very large number of scientists,» says Trounson, an Australian native who pioneered in vitro fertilization in the 1980s and relocated to California to head up the CIRM in December 2007.

«A large number of quiescent hematopoietic stem cells was activated simultaneously when the epigenetic control provided by genomic imprinting was removed,» explains Venkatraman.

But if homologous recombination could be worked out in human (embryonic) stem cells, then cardiomyocytes with mutations in ion channels could be derived, as well as a large number of other very useful disease models of other tissues.

Weissman says that most clinical studies of stem cells fail to meet what he sees as key criteria: They should be based on clear, peer - reviewed demonstrations of tissue regeneration, replicated by a large number of independent groups that provide rapid, long - lasting benefits.

The team found that people have large numbers of neural stem cells and progenitors early in life — an average of 1618 young neurons per square millimeter of brain tissue at birth.

To address these limitations, Zimmer and senior study author Lorenz Studer of the Sloan Kettering Institute for Cancer Research developed a simple, efficient, and robust stem cell - based strategy for reliably producing a large number of diverse, functional pituitary cell types suitable for therapeutic use.

«There are large numbers of bone marrow — like stem cells with huge growth potential.»

This is both a useful tool for giving us a better understanding of the genetic and epigenetic program controlling the self - renewal of stem cells, and on a practical side, it could allow us to inexpensively produce large numbers of immune cells, which could then be used for regenerative medicine or immune therapy.»

«The use of nonhuman oocytes for SCNT is currently the only ethically justifiable option given the large numbers of eggs required to derive cloned human stem cell lines,» he said.

Starting with procedures other research teams had previously worked out to convert iPSCs into keratinocytes, Xu's team demonstrated that by carefully controlling the timing of the growth factors the cells received, they could force the iPSCs to generate large numbers of epithelial stem cells.

In the meantime a large number of federally funded human embryonic stem cell projects have been placed on hold, and even more are potentially at risk.

SCNT requires a large number of eggs and produces very few stem cell lines.

Embryonic stem cells (ESCs) represent a source for the large numbers of modified EPCs required to therapeutically inhibit tumorigenesis [3], although patient - specific induced pluripotent stem cells (iPSCs) represent a more attractive option.

But, by focusing on tissue obtained from mouse embryos, the Salk researchers were able for the first time to identify and isolate a sufficiently large number of fetal breast stem cells to begin to understand how their GPS works.

The largest number of adult stem cells is present in the umbilical cord blood and in bone marrow and they have been used effectively for decades to treat cancers, blood and immune disorders.

The use of human embryonic stem cells, as opposed to patient blood, as the starting material for AST - VAC2 provides a scalable system for the production of a large number of vaccine doses in a single lot, reducing manufacturing costs, enabling «off - the - shelf» availability, and ensuring product consistency.

In an attempt to bring patient - specific induced pluripotent stem cell (iPSCs) technology closer to the clinic, researchers have created iPSCs from patient - derived chondrocytes, using an non-integrative reprogramming method, and used these to then create large numbers of cartilage producing cells.

Previous research from the laboratory of Dan S. Kaufman at the Stem Cell Institute, University of Minnesota, USA has demonstrated that large numbers of Natural Killer (NK) immune cells with potent anti-HIV activity [1] can be derived from hESCs and iPSCs [2, 3], although they lack antigen specific recognition receptors [4, 5].

Due to the large number of hES cells and human induced Pluripotent Stem (hiPS) cells needed by I - Stem's research groups, the development of large - scale culture systems for expansion and differentiation of those cells is critical.

Excitingly, because stem cells can produce such large numbers of neurons, we can even test for and identify new drug candidates using patient specific neurons.

Stem cell therapy safety and efficacy has to be established in a larger number of individuals and with a longer follow - up duration.