Sentences with phrase «large numbers of them cause»

However, if the dog or puppy becomes run down or immunosuppressed, for example, because of illness, stress or malnutrition then the immune system can not keep the mites under control and large numbers of them cause the disease demodicosis.

While there may be a much larger number of causes of cleft palates than I am aware of, these are the toxins that may cause cleft palates (or other birth defects, if administered during pregnancy) that I know of:

Not exact matches

Bankers are warning that the large number of withdrawals are causing branches to run out of money.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

These crises began in the emerging world and caused very substantial damage to the economies and financial systems of a large number of emerging market economies.

A large number of people declaring bankruptcy or defaulting on their loans would have caused their credit scores to plummet, which in turn would affect the average.

On 19 June 2011, a security breach of the Mt. Gox bitcoin exchange caused the nominal price of a bitcoin to fraudulently drop to one cent on the Mt. Gox exchange, after a hacker used credentials from a Mt. Gox auditor's compromised computer illegally to transfer a large number of bitcoins to himself.

To spread the word about a project to the largest number of users, in hopes that they will spread the word further, generating massive interest in the project, and eventually causing the price of the airdropped token to rise dramatically.

Members of the Council pointed out that further GDP revisions are possible for 2015, with the release of 2015 tax data in 2018 having the potential to cause the largest update to the 2015 numbers.

He repeats his description of the ways bad charity (the Great Society) drove out good charity (religiously based groups): It reinterpreted the causes of poverty as exclusively material and environmental; its bureaucracy tried to reach ever - larger numbers of poor people with a decreasingly personal strategy for fighting poverty; it dismissed the role of volunteers in favor of professional social workers; and it removed the incentives for work, saving, and marriage.

The «STAND UP» event seta national and global record in the Guinness World Records for the largest number of people to stand up for a cause... Lutherans across the U.S. participated in the event organised as part of «ONE: The Campaign to Make Poverty History», in cooperation with the United Nations» Millennium Campaign.»

Through the Network, the church has access to a large number of child - care providers well aware of the problems caused by our national policy of child «care - lessness.»

Therefore we can say winning the War is Not by The Large Well Trained Number of Armies or Number of Equipments or Higher the Technologies an Army had but it is rather more about how much faith you have in course and cause!?

Time is a precious commodity on most campuses, yet large numbers of students volunteer their time to support worthy causes.

Probably one of the main causes for the increasingly large numbers of divorces or separations in the usual family group is simply that husband or wife become bored or «fed up» with the narrowness and restrictions they meet.

«This has caused a large generation gap in both attitudes toward premarital sex and number of sexual partners,» she explained in a statement.

When he had built up his Turkish forces to seventy thousand men, the presence of such a large number of soldiers in Baghdad was causing discontent among the people of the city so the Caliph ordered new housing built especially for the army.

After all, a very large number of embryos die of natural causes in their first month without our ever knowing about them, much less grieving for them.

The next stage was to accept that in many entities we have to consider a large number of interacting components, and processes of cause - effect which are not simply linear, but may interest either by being linked into networks, or by various types of feed - back interaction, positive or negative and so on.

The number of unborn and children who have died due to natural causes is literally thousands of times larger than those killed by the actions of human dictators.

A large number of things can cause interference with wireless monitors, and this includes things like radio signals, wireless signals from other types of wireless devices that might be in your home or in neighbor's homes, etc. even microwave ovens can cause interference on a wireless signal.

Some lactation experts believe that hyperlactation is caused by a large number of alveoli, or milk producing glands.

This is especially true during the winter, when many of the viruses that cause colds are circulating in larger numbers.

Given the structural damage caused by the earthquake to water supply systems, there is an additional risk of water borne diseases affecting large numbers of the urban, rural and displaced populations.

I have read that particularly in American cities there were large numbers of infant deaths caused by the contaminated milk.

The cause that prompted him to speak at the Cambridge Union and at other universities, for example, was the campaign for the Living Wage, a wage meant to cover the costs of life that the current minimum wage does not and one which the Cambridge newspaper «Varsity» recently revealed was not being extended to large numbers of low - earning workers within our multi-billion pound University.

«In the summer of 2014, we had a large number of special ed [ucation] students move into our district that were not budgeted for, which caused us to expend more than half - a-million dollars in additional funds to cover the cost of these students» tuitions and additional transportation for those students,» says Burnell.

SERAP believes that causing unspeakable hardships or aggravating the suffering of large numbers of Nigerians ought to constitute an inhumane act of a nature amounting to a crime against humanity, for which the most appropriate forum of redress is the ICC.»

• The State Emergency Operations Center has received reports that several farms were impacted by the flood waters causing a large number of dead livestock and potential hazardous waste material due to those deaths.

Mr Fry, who used to have the largest number of Twitter followers before he was overtaken by Sarah Brown, retweeted the letter yesterday, causing 1,000 visitors per minute to LabourList, which reprinted the letter, and crashing the site.

This caused large numbers of non-college-educated working people, a largely Republican demographic, to change from working one job to working two or more, often with strange and stressful schedules, in order to preserve approximately the same income level.

This unfortunate development is widely believed to have been caused by congestion in our Senior High Schools due to the large numbers of students admitted after government rolled out the Free SHS scheme.

«A weapon of mass destruction (WMD or WoMD) is a nuclear, radiological, chemical, biological or other weapon that can kill and bring significant harm to a large number of humans or cause great damage to human - made structures (e.g. buildings), natural structures (e.g. mountains), or the biosphere.»

The seller would also have to face the reactions from its own citizens of basically abandoning a bunch of them and causing a schism that most likely separates a large number of families.

The large number of tourists who ride the boat take too long to get off and have been causing delays on the line, the Department of Transportation recently said.

There have been a number of large - scale subway disruptions this year, including a recent Con Edison power outage that caused a delays on 12 lines.

This «Alabama paradox» was caused by an algorithm known as the largest remainder method, which was used to round the number of seats a state would receive under strict proportionality to a whole number.

Although some scientists presumed the larger number of very old people in later years was due simply to a larger population base, the new data show the main cause is actually increased survival after age 70.

The researchers now are studying some of the master genes to determine whether modifying them also causes changes in large numbers of other genes.

However, the researchers say the findings are consistent with a large number of studies linking road traffic noise and hypertension, which is a leading cause of stroke.

«Essentially, they showed me that a large number of traffic incidents are caused by medical conditions while driving, specifically cardiovascular events, such as myocardial infraction and myocardial ischemia,» says Najarian, director of data science at the Michigan Center for Integrative Research in Critical Care.

Excess amounts from human activities often end up in rivers, streams and coastal environments, causing algal blooms, loss of sea grass and low oxygen levels in the water, which can kill large numbers of fish and other organisms.

Fat cells cultured from the body mass index of a morbidly obese patient cause multiple myeloma cells to anchor to a much greater extent than normal cells and produce a significantly larger number of blood vessels to sustain the cancer cells.

Infections are the cause of large numbers of infant deaths during the first four weeks of life and half those deaths take place in sub-Saharan Africa.

The number of veterans at risk is large: traumatic brain injury caused by explosive blasts is thought to afflict about 20 percent of the 2.3 million servicemen and women deployed in combat since 2001, according to a team of researchers from Boston University, New York Medical College and the Veterans Affairs Boston Healthcare System.

In the era of online social media, network contagion effects allow social causes to reach a large number of interconnected individuals fast, efficiently, and at low cost.

Was it humankind or climate change that caused the extinction of a considerable number of large mammals about the time of the last Ice Age?

So in the May issue, Lester Brown of the Earth Policy Institute, he writes an essay in which he raises sort of the specter that potentially, in the decades to come, that if we are not careful, that these problems with maintaining a sufficient food supply could get bad enough that it actually would threaten the state of civilization globally; that it just could cause widespread chaos, cause a large number of failed states and trigger [an] enormous number of problems down the line.

«I anticipate a large number of follow - up studies searching for causes and the best treatment option for this newly identified morbidity associated with carotid narrowing.»

So when a large number of cholera cases caused by a new strain named O139 started turning up in India, WHO officials were understandably alarmed.