Sentences with phrase «large phenotypic effect»

The alternative model is that mutations of large phenotypic effect underlie most of these traits in dogs and that the same variants have been transferred to a wide diversity of dog breeds leading to phenotypic diversity from a narrow genetic base [5], [8], [12].

Not exact matches

We are particularly interested in assessing whether the majority of phenotypic variation among breed - affiliated dogs is a consequence of QTLs of large effect or whether much of the variation is attributable to many QTLs of modest or small effect.

The largest numbers of variants identified by genome - wide association are copy - number changes, which have a greater phenotypic effect than do single nucleotide polymorphisms.