Sentences with phrase «large scaffold protein»
The huntingtin gene encodes a large scaffold protein, with many interaction partners, which is thought to be involved in intracellular trafficking.
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The Meiler laboratory develops technologies to engineer protein, for example through assembly of large protein scaffolds from fragments (Fortenberry, C.; et al.; «Exploring symmetry as an avenue to the computational design of large protein domains»; JACS 2011; 133; 18026 & Eisenbeis, S.; et al.; «Potential of Fragment Recombination for Rational Design of Proteins»; JACS 2012; 134; 4019).
Large amounts of this protein create a cellular matrix, or a scaffolding, to which other structural proteins attach themselves to reform the wound, including more collagen itself.