Sentences with phrase «large sequencing gaps»

The device has made it possible for researchers to study bacteria and viruses in the field, but its high error - rate and large sequencing gaps have, until now, limited its use on human cells with their billions of nucleotides.

Not exact matches

Using SHIMS, the lab greatly improved the human X reference sequence, accurately assembling three large amplicons, identifying previously unknown palindromes, and ultimately shortening the entire length of the sequence by eliminating four major gaps.

Three large groups of geneticists independently set out to fill the gaps, adding hundreds of fully sequenced genomes from Africa, Australia, and Papua New Guinea to existing databases.

Importantly, our decision to use a synthetic genome meant that placed chain - gaps larger than our window size would spread across window boundaries, ensuring that genomic bins would contain no more than 200 kb of sequence.

The new PcyM assembly is significantly larger than the PcyB assembly (31 versus 26 Mb)(see Table 1), more contiguous (N90 of 370kb versus 3.9 kb), and has no sequencing gaps (0 versus 1943 gaps).

Large - scale sequencing retained some advantages (capacity and experience) over the rest of the research community, but the gap was rapidly shrinking.

Unfolding as an American epic of the small and incidental, Graham's sequences of photographs span gaps of time and place, their interweaving of narrative threads, their digressions and shifts of scene creating imaginative spaces and a sense of the country at large, while mirroring its social divisions and discrepancies alongside the unpredictable fluctuations of life.