Sentences with phrase «large sequencing project»

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When the team looked for it in data from the Human Microbiome Project, a large - scale project to sequence the DNA of all the microbes that live in and on our bodies, they found that it was present in 73 per cent of all 466 faecal sProject, a large - scale project to sequence the DNA of all the microbes that live in and on our bodies, they found that it was present in 73 per cent of all 466 faecal sproject to sequence the DNA of all the microbes that live in and on our bodies, they found that it was present in 73 per cent of all 466 faecal samples.

By the end of this year, hundreds of children with unexplained forms of intellectual disability and developmental delay will have had their genomes decoded as part of the first large - scale, national clinical sequencing projects.

Scientists and clinicians hope that the lessons learned in these initial large - scale clinical sequencing projects will inform genomic medicine as it reaches more patients and moves to other specialties, such as neurology and cardiology, and even to routine health care.

The researchers believed that mapping techniques commonly used by the larger projects, while efficient, limited their ability to find unique sequences among all the copies and duplications in this region.

When the researchers expanded their search to include all the data from the Human Microbiome Project, a large - scale project to sequence the DNA of all the microbes that live in and on our bodies, they found that the same virus was present in 73 per cent of all 466 human faecal sProject, a large - scale project to sequence the DNA of all the microbes that live in and on our bodies, they found that the same virus was present in 73 per cent of all 466 human faecal sproject to sequence the DNA of all the microbes that live in and on our bodies, they found that the same virus was present in 73 per cent of all 466 human faecal samples.

As large - scale genome sequencing projects, such as the Human Genome Project, near completion, the research community's focus is shifting toward efforts to determine functional information about these sequenced genes.

Hadfield and his colleagues are doing large - scale genomic analyses of different tumor types, as part of the massive Genomics England project to sequence 100,000 British genomes.

In the largest measles genomics project to date, the scientists performed DNA sequencing for 27 different measles viruses.

Large - scale gene - sequencing projects are revealing hundreds of autism - associated genes.

Most if not all large scale genome sequencing projects are funded by agencies that, now usually the NIH with the National Science Foundation, that require you to release your data immediately.

Bioinformatics tries to solve biological problems by using computers to make sense of the large amounts of data that arise from sequencing and other large - scale projects.

Large - scale genome sequencing efforts, like the Human Microbiome Project, have focused on the community of microorganisms that live in the human gut.

The IU scientists discovered the unprecedented lack of Complex I in a multicellular organism during a larger project to expand the number of parasitic plants that have undergone mitochondrial genome sequencing.

So far, the project includes 271 sequences of 120 species that were collected during the Bush Blitz surveys, Australia's largest nature discovery project.

«Tim and I were able to work very closely in all the steps of the project from the experimental design in the wet lab to the final analysis of the results; the major challenge was how to handle the very large number of barley samples and for this we designed a novel approach to sequencing that exploited deep results in combinatorics,» Lonardi said.

But that project sequenced the C. robusta species of coffee, a large and low - quality bean that has lost its popularity in the last few decades.

The Wellcome Trust's Sanger Centre is expected to make the little striped swimmer the target of a new large - scale sequencing project, Philip Ingham, a developmental geneticist at the U.K.'s University of Sheffield, announced last week at the Cold Spring Harbor Laboratory in New York.

The newest study from the Autism Speaks MSSNG project — the world's largest autism genome sequencing program — identified an additional 18 gene variations that appear to increase the risk of autism.

When the team checked the DNA of a larger group of nearly 111,000 people, they found that about one in 200 carried one of the four APOC3 variants, reported Jacy Crosby of the University of Texas Health Science Center, Houston, who represented a large consortium called the National Heart, Lung, and Blood Institute Exome Sequencing Project.

Also today, NHGRI and the National Cancer Institute (NCI), both part of the National Institutes of Health (NIH), announced that all three sequencing centers will devote a significant part of their efforts to The Cancer Genome Atlas (TCGA) Pilot Project, which is testing the feasibility of a large - scale, systematic approach to identify important genomic changes involved in cancer.

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(1940 ---RRB- Gauer - Henry reflex gauge boson gauge theory gauss (unit) Gauss, Carl Friedrich (1777 — 1855) Gaussian distribution Gay - Lussac, Joseph Louis (1778 — 1850) GCOM (Global Change Observing Mission) Geber (c. 720 — 815) gegenschein Geiger, Hans Wilhelm (1882 — 1945) Geiger - Müller counter Giessler tube gel gelatin Gelfond's theorem Gell - Mann, Murray (1929 ---RRB- GEM «gemination,» of martian canals Geminga Gemini (constellation) Gemini Observatory Gemini Project Gemini - Titan II gemstone gene gene expression gene mapping gene pool gene therapy gene transfer General Catalogue of Variable Stars (GCVS) general precession general theory of relativity generation ship generator Genesis (inflatable orbiting module) Genesis (sample return probe) genetic code genetic counseling genetic disorder genetic drift genetic engineering genetic marker genetic material genetic pool genetic recombination genetics GENETICS AND HEREDITY Geneva Extrasolar Planet Search Program genome genome, interstellar transmission of genotype gentian violet genus geoboard geode geodesic geodesy geodesy satellites geodetic precession Geographos (minor planet 1620) geography GEOGRAPHY Geo - IK geologic time geology GEOLOGY AND PLANETARY SCIENCE geomagnetic field geomagnetic storm geometric mean geometric sequence geometry GEOMETRY geometry puzzles geophysics GEOS (Geodetic Earth Orbiting Satellite) Geosat geostationary orbit geosynchronous orbit geosynchronous / geostationary transfer orbit (GTO) geosyncline Geotail (satellite) geotropism germ germ cells Germain, Sophie (1776 — 1831) German Rocket Society germanium germination Gesner, Konrad von (1516 — 1565) gestation Get Off the Earth puzzle Gettier problem geyser g - force GFO (Geosat Follow - On) GFZ - 1 (GeoForschungsZentrum) ghost crater Ghost Head Nebula (NGC 2080) ghost image Ghost of Jupiter (NGC 3242) Giacconi, Riccardo (1931 ---RRB- Giacobini - Zinner, Comet (Comet 21P /) Giaever, Ivar (1929 ---RRB- giant branch Giant Magellan Telescope giant molecular cloud giant planet giant star Giant's Causeway Giauque, William Francis (1895 — 1982) gibberellins Gibbs, Josiah Willard (1839 — 1903) Gibbs free energy Gibson, Edward G. 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Recent and rapid advances in technologies that permit large - scale creation and synthesis («writing») of longer pieces of synthetic DNA, as well as the advent of extremely fast, cheap and accurate sequencing («reading») of DNA, have changed our collective thinking about the feasible size and scope of projects in many labs.

In the same way that the fly genome paved the way for larger projects, including sequencing the human genome, FlyEM may ultimately contribute to our understanding of the human brain by establishing a fly «connectome» — a map that shows how all neurons in the fly brain are connected to each other.

Abstract: We report the discovery of a low - mass companion orbiting the metal - rich, main sequence F star TYC 2949 -00557-1 during the MARVELS (Multi-object APO Radial Velocity Exoplanet Large - area Survey) Pilot Project.

The large volume of sequence data from novel organisms generated by metagenomic projects has triggered the development of specialized databases and tools focused on particular groups of organisms or data types.

... ▽ More We report the discovery of a low - mass companion orbiting the metal - rich, main sequence F star TYC 2949 -00557-1 during the MARVELS (Multi-object APO Radial Velocity Exoplanet Large - area Survey) Pilot Project.

A research project launched today will blend the muscle of a huge Chinese genome sequencing center with the funding prowess and ambition of a high - profile American advocacy group, to create the world's largest library of sequenced genomes from people with autism.

In the meantime, we are in the midst of large - scale sequencing efforts for the Centers for Complex Disease Genomics (CCDG), Alzheimers Disease Sequencing Project (ADSP), and Gabriella Miller Kids First (GMKF) insequencing efforts for the Centers for Complex Disease Genomics (CCDG), Alzheimers Disease Sequencing Project (ADSP), and Gabriella Miller Kids First (GMKF) inSequencing Project (ADSP), and Gabriella Miller Kids First (GMKF) initiatives.

The scientists used data from the UK10K Project — a massive, whole ‐ genome sequence ‐ based resource of the general European population; the NIH - funded 1000 Genomes Project, one of the world's earliest efforts to sequence the genomes of a large number of people; and data from several other studies.

Success of this project will provide answers to a number of major evolutionary questions, and will help develop innovative third - generation sequencing approaches for small organisms with large genomes, said Johanna Cannon.

«In our research project on pediatric leukemia we plan to use Gemcode to define the exact chromosomal breakpoints of large scale chromosomal rearrangements and repetitive sequences that are typical for leukemic cells, but are difficult to characterize in short sequence reads,» said Professor Ann - Christine Syvänen, who leads the Molecular Medicine group.

The Ensembl (http://www.ensembl.org/) project provides a comprehensive and integrated source of annotation of large genome sequences.

The National Institute on Aging (NIA) and the National Human Genome Research Institute (NHGRI) were asked to develop and execute a large scale sequencing project to identify AD risk and protective gene variants.

More recently, in a joint initiative with the BBMRI - LPC project (Biobanking and Biomolecular Resources Research Infrastructure — Large Prospective Cohorts) and the Wellcome Trust Sanger Institute, the CNAG - CRG launched a call to promote the use of sequencing technologies for the identification of novel causative variants and genes and to molecularly diagnose rare disease patients.

Being backed by several large organizations, including NASA and the Defense Advanced Research Projects Agency, we are sure to see big changes coming our way as genetic sequencing moves towards being as easy to extract as someone's pulse.

The 100,000 Genomes Project, is the first major large - scale whole genome sequencing project in theProject, is the first major large - scale whole genome sequencing project in theproject in the world.

In a large - scale sequencing project in approximately 200 pedigrees with suspected X-linked intellectual disability, two protein - truncating mutations in SLC9A6 were found [5].

Assistant Professor Johan Bengtsson - Palme (University of Gothenburg) heads a biodiversity research project recently granted financing of large - scale sequencing via the SciLifeLab National Sequencing Projects isequencing via the SciLifeLab National Sequencing Projects iSequencing Projects initiative.

This discriminatory power will only increase as ambitious large - scale sequencing projects like CCDG make their data publicly available.

The Swedish Biodiversity Program aims to target biodiversity of bacteria, viruses, archaea and eukaryotes and combinations thereof to promote large research projects aiming to uncover and understand genomic variability in nature by use of massively parallel sequencing and microbial single cell analysis.

Within the SweGen project, large - scale DNA sequencing methods were used to analyse the whole genome of 1000 individuals from different parts of the country.

With support from the Knut and Alice Wallenberg foundation SciLifeLab has launched a national sequencing project initiative that serves to support and advance large - scale genomic research in Sweden.

As a part of this arrangement, it's been agreed that sequence data will be integrated into the large, global set of genetic data produced by the MalariaGEN P. falciparum Community Project and released with user - friendly web tools to maximise the value of these findings for the scientific community.

I have expertise and experience in developing high throughput pipelines for DNA sequencing at large scale, having contributed in a pivotal manner to the sequencing and completion of the Human Genome Project.

Large - scale sequencing efforts like the 1,000 Genomes Project and The Cancer Genome Atlas now consider BAM the standard format for data exchange.

Under Dr. Mullikin's leadership, NISC has begun to apply genome sequencing technologies to clinical research, especially with its largest project, called ClinSeq, for which NISC has generated more than 500 whole - exome sequences to date.

Since then, I've participated in the International HapMap Project, the Cancer Genome Atlas, the 1,000 Genomes Project, the Alzheimer's Disease Sequencing Project, and other large - scale collaborations.

Also, BWA generates alignments in SAM / BAM format by default, which is convenient for our large - scale sequencing projects where BAM files are becoming the standard format.

Complete genome sequences from more than a thousand organisms as well as data from large - scale protein structure determination projects are also publicly available.

In it, the authors review bioinformatics approaches for evaluating single - base substitutions in both coding and noncoding regions, with an emphasis on large cancer resequencing efforts including the Tumor Sequencing Project, the Cancer Genome Atlas (TCGA), and the AML1 cancer genome.