Sentences with phrase «large treatment study»

The inclusion criteria of the large treatment study on aggressive children were a clinical or borderline - clinical score (T ≥ 65) on the externalizing subscale of the parent - report form of the Child Behavior Checklist (CBCL; Achenbach 1991) and sufficient knowledge of the English language to complete the questionnaires without an interpreter.

This study was part of a larger treatment study on aggressive children that aimed to determine the processes of change related to treatment success (Granic et al. 2007).

Not exact matches

Pagan said that a larger, more comprehensive study must be done before determining the drug's true impact, but if the drug's effectiveness is confirmed in such tests, nilotinib could become the first treatment to impede the killing of brain cells that's consistent with Parkinson's, according to NPR.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Although Lu - PSMA - 617 put up good numbers in its small single - arm study, it still needs to outperform a physician's choice of approved treatments in a much larger global trial.

Although these results sound promising, Mathew cautions that more studies on larger groups of people need to be done before he can recommend capsaicin as a definite treatment for cluster headaches.

In order to assess the efficiency and safety of domperidone, researchers Catherine Paul et al. analyzed both the limited studies available on maternal and infant exposure to the stimulant as well as larger studies focused on its use in gastrointestinal disorder treatment.

However, given that the largest study on chiropractic treatment with the best scientific design showed NO DIFFERENCE in overall crying times, my suggestion would be to focus on some of the other more promising options instead.

Large - scale studies of SM treatment are needed.

In Soweto, for instance, there is a large hospital facility known throughout the world as a great center for the study and treatment of traumatic injuries.

UKPDS - Implications for the care of people with Type 2 diabetes The United Kingdom Prospective Diabetes Study (UKPDS), the largest clinical research study of diabetes ever conducted, has provided conclusive evidence that the life threatening complications of Type 2 diabetes (non insulin dependent diabetes) can be significantly reduced by appropriate treatStudy (UKPDS), the largest clinical research study of diabetes ever conducted, has provided conclusive evidence that the life threatening complications of Type 2 diabetes (non insulin dependent diabetes) can be significantly reduced by appropriate treatstudy of diabetes ever conducted, has provided conclusive evidence that the life threatening complications of Type 2 diabetes (non insulin dependent diabetes) can be significantly reduced by appropriate treatment.

To that goal, Smith is launching a radiation study looking at two - to - two - and - a-half weeks of treatment of external beam treating a large area surrounding the tumor bed.

A new study by a team of scientists from the University of Malta and the Institut de Génétique Moléculaire de Montpellier (CNRS / Université de Montpellier) could help develop treatment strategies for a crippling disorder that was the focus of the Ice Bucket Challenge, the world's largest global social media phenomenon.

Research Fellow, Mette Andersen, who led the study, said, «This is the largest population - based study to examine whether levothyroxine treatment for patients with subclinical hypothyroidism can affect their mortality.

Previous studies also demonstrate that moderate hypo - fractionated radiation therapy (HRT), consisting of daily treatment for one month using a larger dose per treatment, provides a similar low risk of recurrence, and may even be lower with HRT than CRT.

She says the results merit a larger study to discover the best timing and combination of treatments.

«This study demonstrates the value of using the SEER database to analyze factors associated with surgery as a treatment for localized pancreatic cancer in a large number of patients over a prolonged period of time,» says Dr. Kim, who is also Chief Medical Officer of UH Seidman Cancer Center and the Charles Hubay Professor at Case Western Reserve School of Medicine.

Unlike «big data» genetic studies, which have loosely linked hundreds of genetic changes to schizophrenia but can not explain varying symptoms, the new study revealed distinct disease versions that may affect large slices of patients and enable precision treatment design, say the authors.

A climate scientist studying the cooling effects of various environmentally engineered roofing treatments recently led a tour of a large postal facility's green roof

Bride and his co-authors analyzed a large, national sample of Substance Use Disorder counselors from the National Institutes of Health - funded National Treatment Center Studies.

The task force analyzed several large studies and determined that the benefits of screening and treatment did not outweigh the risks.

The study, «Prevalence of hypertension, awareness, treatment and control in the Hispanic Community,» led by Dr. Paul D. Sorlie of the National Heart, Lung, and Blood Institute (NHLBI), sampled 16,400 individuals, making it one of the largest and most rigorous health studies of the Hispanic community.

If the findings can be replicated in larger studies, it might be possible for doctors to identify which people will later develop schizophrenia, and offer them preventative treatments, he says.

«If we can confirm these results in the larger study that we are planning to begin soon, this imaging system may allow us to personalize breast cancer treatment and offer the treatment that is most likely to benefit individual patients,» says Hershman, who is also a professor of medicine and epidemiology at Columbia University Irving Medical Center.

If this 10 - lipid test is validated in larger studies, it could help researchers to develop treatments for Alzheimer's that halt or slow the disease before it even begins.

«Such biases, conscious or unconscious, can make candidate medical treatments look better than they actually are, the authors of the analysis warn, and lead to eye - catching results that can't be replicated in larger or more rigorous animal studies — or in human trials.»

Although changes in treatment methodology still have to be studied, Dr. Cripe believes it may be that the timing of various treatments is what matters, and that perhaps initially suppressing immunity could allow the virus to infect a large number of tumor cells before relieving the immunosuppression to allow the body's own T cells to fight off the tumor.

He also began consulting on a large first - episode treatment program in four cities in Norway and Denmark, applying insights from earlier studies that had convinced him that combining multifamily psychoeducation, social services, and low - dose antipsychotics could prevent relapse among young, first - episode patients.

All families in our study completed the treatment, and half of them experienced a large or very large improvement of the behavioral problems,» says Mats Johnson.

For the major nutrient phosphorus, measurements from this study confirmed earlier calculations: inputs from wastewater treatment plants account for 50 per cent of phosphorus loads in large Swiss rivers.

«I anticipate a large number of follow - up studies searching for causes and the best treatment option for this newly identified morbidity associated with carotid narrowing.»

«If these findings are confirmed in larger studies, they hold significant implications for new treatment targets and open the door for more questions such as: should these patients be treated more aggressively with medications, cognitive rehabilitation, or even surgery to open up the artery,» said Lal.

«This interesting study looking at maternal ethnicity provides useful data based on a large number of women undergoing fertility treatment.

The study estimates that there are around 20,000 to 25,000 potential patients that could receive mechanical thrombectomy within the U.K. if used as a mainstream treatment for large vessel clots.

It represents the first large scale study of individuals seeking treatment for gambling problems in the UK, at a time when this disorder is being re-classified alongside drug addiction as the first «behavioural addiction».

«We don't know what exposure is leading to this susceptibility to dietary glutamate, but this pilot study suggests the need for a large - scale clinical trial, since dietary change could be an effective low - cost treatment option for developing countries.»

Aggressive treatment of high blood pressure comes with risks, and the study, a large clinical trial sponsored by the National Institutes of Health, has not yet been peer - reviewed or published.

«Our results provide a large body of evidence demonstrating that the harmine drug class can make human beta cells proliferate at levels that may be relevant for diabetes treatment,» said senior study author Andrew Stewart, MD, Director of the Diabetes, Obesity and Metabolism Institute at the Icahn School of Medicine.

Then there's the larger question of whether science should study treatments for a condition that is not, in mental health terms, a problem.

«While this was the first head - to - head comparison of these two treatments, larger prospective studies will be needed to confirm these findings.»

... Finally, this study draws attention to the need for large controlled clinical trials to determine if a combination of fall prevention strategies and treatment with bone - active drugs might produce additive benefits on fractures, especially in high - risk populations such as those living in nursing homes.

Funded by the National Institute of Mental Health, STAR * D was the largest and longest study of depression treatment ever conducted.

A new study, which is the largest study within this field of research so far, shows that DFI analysis can be used for selecting the most efficient treatment to involuntarily childless couples.

«We report here a gene therapy dose - finding study in a large animal model of a severe muscle disease where a single treatment resulted in dramatic rescue,» said Childers.

The investigators acknowledge that there are possible confounding factors in the study (notably that maternal health information was incomplete in the second and third trimesters of pregnancy), but the design of this large study in a series of egg donation treatments ruled out any possibility that the weight of the egg donor (all defined as of normal weight) could affect results in the recipient.

The largest study of survivors of the largest recorded outbreak of Ebola virus disease found they commonly reported complications such as vision, hearing and joint pain problems up to months after they were discharged from an Ebola treatment facility.

The largest study of survivors of the largest recorded outbreak of Ebola Virus Disease found they commonly reported complications such as vision, hearing and joint pain problems up to months after they were discharged from an Ebola treatment facility.

Two different family - based therapies are both effective at combating anorexia nervosa in teenagers, according to the largest study ever to compare two such treatments for the life - threatening eating disorder.

His colleague Alex Liddle, an Arthritis Research UK clinical research fellow who ran the study, added: «Partial and total knee replacements are both successful treatments and a large proportion of patients with end - stage knee osteoarthritis are suitable for either.

This study is the first phase of a larger initiative to develop and pilot test Critical Time Intervention, a transitional assistance model for individuals leaving residential substance abuse treatment.