Sentences with phrase «largely diseases of aging»

Because neurodegenerative disorders like PD are largely diseases of aging, modeling them in a culture dish using neurons grown from iPS cells has been thought to be exceedingly difficult, if not impossible.

Not exact matches

Why have we made more progress on certain diseases while other mass - scale killers, like chronic obstructive pulmonary disease (COPD), are largely off of people's radars and so difficult to treat in an age of therapies which can resemble magic?

I can't help but consider the fact that due to the (largely uncontrollable) circumstances of my birth, I will spend the day celebrating while roughly 24,000 children under the age of five die from preventable, treatable diseases.

Surviving past age 100 means they've largely evaded the scourges that kill their peers before they reach their 90s (what's called compressed morbidity), or sidestepped the worst aspects of these life - threatening diseases — even if they strike sooner — because they have combinations of protective genes, what researchers call «greater functional reserves.»

«It is well established that there is a «hyper - inflammatory phenotype» based largely on genetic factors that is of value in protecting the young from bacterial infection before they have made IgG antibodies to the bacteria they encounter; but which, in later life predisposes to the inflammatory diseases of old age.

Type 1 diabetes is an autoimmune disease, type 2 diabetes is a lifestyle disease largely caused by being overweight, some researchers have suggested that Alzheimer's disease is a type 3 diabetes, and here evidence is presented for the existence of a type 4 age - related diabetes:

Current research on aging has largely focused the molecular mechanisms of age - related diseases, and mitochondrial dysfunction has been associated with several human diseases of aging.

Erosion of telomeres has long been associated with diseases of aging, but how telomere length affects human disease has remained largely a mystery.

Advanced age is the main risk factor for most chronic diseases and functional deficits in humans, but the fundamental mechanisms that drive ageing remain largely unknown, impeding the development of interventions that might delay or prevent age - related disorders and maximize healthy lifespan.

This is perplexing, considering that it's well - established that the major diseases of our age, including heart disease, type - 2 diabetes, and colon cancer, are all largely caused by unhealthy diet and lifestyle practices (1, 10, 14).

Approximately 2 - 5 % of stray cats (compared with approximately 15 - 20 % of stray dogs) in shelters are returned to their guardians and more than 70 % of cats (compared with about 56 % of dogs) are put to death in shelters each year, largely, shelters cite, because of a lack of adopters, no space, age, and spread of disease.

According to the American Heart Association this $ 545 billion increase in costs for treating heart disease and stroke is largely due to the aging of the population.

The onset of end - stage renal disease among non-Indigenous people occurs largely among older people, but rates among Aboriginal and Torres Strait Islander people are high from the 25 - 34 years age group.

Not only can symptoms be distressing, AUD can trigger a cascade of lifelong adverse outcomes, such as: other mental disorders, suicide, serious unintentional injury, illicit drug use, antisocial behaviour, as well as early onset of heart disease, stroke and cancer.3 While the peak age for the onset for AUD is 18 — 24 years, the factors that predict the transition from alcohol use to AUD symptom onset and from symptom onset to diagnosable AUD remain largely unknown.