Sentences with phrase «largely unknown»

The deeds of Oskar Schindler may have gone largely unknown but for a chance conversation between Australian author Thomas Kenneally and a luggage repair shop employee in LA.

Most members of her family, friends don't remembered even on her birthday to send gifts or call her, receiving such overwhelming attention from the man whom she met on the Internet so, even if he is largely unknown to her, meant a lot to her.He made her feel very needed and wanted again, after her recent divorce.The problem of solitude has caused many men and women in the United States and other Western countries to lose millions of dollars every month for dating scams.

Tinder made its debut in South Korea in 2015 but despite its international popularity, the dating app is still largely unknown in a country notorious as the graveyard of many foreign - born startups and companies including Uber and Google.

Although scientists have identified a handful of genetic mutations that are linked to schizophrenia as well as autism, the role that specific genes and environmental factors play in the disorders is still largely unknown.

Alzheimer's disease affects as many as 5 million people in the U.S., and the cause is largely unknown (although genes play a role).

Furthermore, it is largely unknown whether resting metabolic rate (RMR) or thyroid hormones, factors that can influence energy expenditure [28], might be also involved in the potential effects of PFASs on weight regulation [29,30].

The long - term side effects of Truvada — for instance, whether the decrease in bone density might lead to fractures — are still largely unknown, which raises questions about the advisability of prescribing this expensive drug to healthy people, HIV experts say.

Both studies concluded that diet has a profound effect on the diversity of gut bacteria, although, Fu said, the «underlying theories of these dietary factors remain largely unknown.»

The truth about rep ranges is something that is largely unknown within the bodybuilding community.

''... it could be hypothesized that PD is, at least in part, a type of «segmental» aging, in which specific, localized, and accelerated aging mechanisms, which for reasons at present largely unknown, markedly affect dopaminergic (DA) neurons in the pars compacta region of the midbrain substantia nigra (SnPC).»

... and that illustrates another point, which is that BPA, parabens, triclosan and the thousands of other chemicals are largely unknown entities.

In type 1 diabetes, there is destruction of the insulin producing cells of the pancreas for reasons that are still largely unknown.

While I'd love to discuss testosterone supplements and their side effects, I can't — testosterone booster side effects are largely unknown, and there's a good reason for that: Boosters are all different.

While I'd love to discuss testosterone supplements and their side effects, I can't — testosterone booster side effects are largely unknown, and there's a good reason for that:

The real truth is that although it sounds good because raspberries are healthy right... in the long - term, supplements like this can help you gain weight because (1) they aren't actually made from raspberries, but rather in a lab; (2) they have never been tested on humans and side effects are largely unknown; and (3) many people gain weight when taking the supplement.

As for other treatments to water, such as spiral tubing, crystals, sunshine, etc. — I believe they all some kind of effect: but exactly what effect is still largely unknown.

Now here's a muscle that is largely unknown but is critical to riding a bike.

The interplay between these and other endocrine signaling systems and its effect on body weight regulation and subjective feelings of hunger and satiety remains largely unknown.

How well a ketogenic works for individuals on the autism Spectrum is largely unknown.

The mechanism of its action, by the time of its wide introduction in the 1990s was largely unknown.

In addition to being an amazing natural sweetener, honey has benefits that have gone largely unknown.

These tools are largely unknown to traditional physicians, but have been available for over 20 years.

Fibre has multiple purported mechanisms of health benefit but the importance of each is largely unknown.

Benefits Of Kefir Kefir Probiotics And Kefir Health Benefits The main reason why kefir grains have remained in circulation around the world despite being largely unknown in mainstream health drink market is their health and medicinal value.

While the reason for this is largely unknown, one theory is that working women look for jobs with more flexible hours when they decide to have a family.

How these longevity pathways regulate adult stem cell homeostasis and aging in mammals still remains largely unknown.

To test the technology, it has to be put into effect — and the consequences of that are still largely unknown.

This compound is known as Transfer Factor and whilst there is a large scientific literature on this subject, the nature and mechanism of action of Transfer Factors are largely unknown.

Aging of the hematopoietic stem cell (HSC) compartment is characterized by lineage bias and reduced stem cell function, the molecular basis of which is largely unknown.

The FISS team would anxiously wait for Boaty to return after being gone for upwards of 48 hours at a time, and in largely unknown marine environments.

The stage of B cell development represented by PEL, how this stage relates to tumor pathology, and how this information may be used to treat the disease are largely unknown.

However, the specific role of these enzymes in cancer is still largely unknown.

The human burden of tuberculosis caused by the bovine tubercle bacillus is still largely unknown.

Despite many recent discoveries about the genetics of ALS, the etiology of sporadic ALS remains largely unknown with gene - environment interaction suspected as a driver.

The evolutionary origins of metabolism, in particular the emergence of the sugar phosphates that constitute glycolysis, the pentose phosphate pathway, and the RNA and DNA backbone, are largely unknown.

Until now, mechanisms involved in dopaminergic circuit formation remained largely unknown.

It remains largely unknown to what extent the local proteome of tumors intrinsically varies.

Despite many recent discoveries about the genetics of ALS, the etiology of sALS remains largely unknown.

Objective: Primary sclerosing cholangitis (PSC) is a genetically complex, inflammatory bile duct disease of largely unknown aetiology often leading to liver transplantation or death.

Dr. Barbé: The molecular mechanisms responsible for the onset and severity of repeat diseases, such as myotonic dystrophy and Huntington's disease, are largely unknown.

To date, it remains largely unknown how major pH regulatory systems and their energetics are affected by trans ‐ generational exposure to near ‐ future acidification levels.

Advanced age is the main risk factor for most chronic diseases and functional deficits in humans, but the fundamental mechanisms that drive ageing remain largely unknown, impeding the development of interventions that might delay or prevent age - related disorders and maximize healthy lifespan.

However, the mechanism responsible for the migration of intestinal cells remains largely unknown.

But CPEBs are not limited to the transcriptionally silent germline; they are also expressed, in various combinations, in somatic cells, yet their role in regulation of mitosis - related gene expression is largely unknown.

He joined the small, «largely unknown» MDI Biological Laboratory in 2010 as an opportunity to transform a summer research station into a global mecca of scientific discovery.

Because Sanger sequencing does not provide the sensitivity to reliably distinguish somatic from germline mutations, the proportion of de novo mutations that occur somatically rather than in the germline remains largely unknown.

Asthma and allergies run in families and are the result of complex interactions between largely unknown genetic and environmental factors.

And I'll end with the thought that if we do decide brown dwarf planets are not uncommon, and that complex life may find ways of evolving on such worlds, then nearby space may be littered with astrobiologically interesting destinations that are largely unknown to us.

For the development and verification of a new method, it would be better to select a nearby galaxy which can be spatially resolved and examined in detail compared to a distant galaxy whose properties are largely unknown.

While the rate at which melting permafrost will add carbon to the atmosphere is largely unknown, a study released February 11 in Proceedings of the National Academy of Sciences at least begins to tackle the problem.