But
the larger impact of the technology is still ahead, in the ways it will integrate with, and alter, classroom practice.
Not exact matches
First, the spread
of McDonald's and the like — all
of whom used
technology and engineering to produce
large volumes
of food at low prices — had an
impact.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a
larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect
of lowering prices or reducing the number
of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease
technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange
impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
With a deep double walled side
impact protection, orthopaedic inner cushion, and anti-rebound
technology, the Doona is also
larger than most
of its peers meaning that your infant can remain in the safest form
of car seat for longer.
With a deep double walled side
impact protection, orthopedic inner cushion, and anti-rebound
technology, the Doona is also
larger than most
of its peers, meaning that your infant can remain in the safest form
of car seat longer.
But, as scientists report in ACS» journal Environmental Science &
Technology, «fracking» operations could have
impacts on water quantity because they are withdrawing these
large amounts
of water from nearby streams, which house aquatic ecosystems and are used by people for drinking and recreation.
The report also provides a closer look at the environmental
impact of building roads and bringing in construction equipment to develop hydro power in Africa and South America; the land - use advantages
of solar
technology; and the costs
of large - scale energy storage.
Because STEP grants are considered institutional grants, projects are more likely to be funded if the plan intends to boost the number
of all science,
technology, engineering, and mathematics graduates — thus, making a
large impact — as opposed to targeting one discipline or underrepresented group.
Jury member Penny Heaton, director
of vaccine development at the Bill & Melinda Gates Foundation, said CureVac's RNA
technology had «the potential for a
large and positive
impact on public health,» in a statement released by the company on 10 March.
With the ever increasing
impact of technology on education, it's nice to see that Olympia in London will be hosting a
large exhibition next week to show off the latest gizmos and computers for broadening young minds.
Comb
technology has already had a
large impact on studies
of how atoms and molecules respond to the strong electric fields obtainable in intense, ultrashort light pulses.
The Innovative and Novel Computational
Impact on Theory and Experiment (INCITE) program promotes transformational advances in science and
technology for computationally and / or data intensive,
large - scale research projects through
large allocations
of computer time and supporting resources at the Argonne and Oak Ridge Leadership Computing Facility (LCF) centers, operated by the US Department
of Energy (DOE) Office
of Science.
This investment with the SFI Research Centre IPIC will enable us to combine our expertise and utilise Tyndall's state
of the art facilities to develop ground breaking early stage
technologies, which will not only have a huge
impact on the future architecture design
of large data centres, but will also improve the power and computational capacity
of new consumer devices and provide robust sensing solutions in the autonomous vehicles and consumer device sectors as well as others.
In addition, the report provides an in - depth discussion
of the broader issues
impacting SMRs, such as the keys to successful deployment for SMRs, comparisons with
larger reactor
technologies, specific applications for SMRs, and the broader issues facing potential customers for SMRs.
«Water desalination and nanofiltration are big applications where, if things work out and this
technology withstands the different demands
of real - world tests, it would have a
large impact,» Karnik says.
«This is the first
of eight
large - scale integrated
technology demonstrations ERA is finishing up this year that are designed to reduce the
impact of aviation on the environment.»
«With nearly three decades» experience supporting primary schools and academies
of all sizes — from village primaries with 80 pupils right through to
large inner city academies with 800 pupils - we see the
impact that
technology is having on education and the challenges this brings.
Whether it's a course on designing cutting - edge
technologies, a practicum on
large - scale distance learning, or a course on evaluating the
impact of educational apps, we concentrate on the cognitive, affective, and social dimensions
of learning, not on the bit rate.
In «The Common Core Takes Hold,» Robert Rothman
of the Alliance for Excellent Education acknowledges a number
of McShane's concerns: states» shrinking budgets will likely
impact the funding necessary for implementation; there is little to no quality monitoring
of the new resources that are being created; the new assessments — and the
technology required to implement them — are hugely expensive; the public at
large is poorly informed and their support for the standards is waning; and a significant drop in student test scores following implementation
of Common Core - aligned assessments is a real concern.
We found that contextual constraints such as availability
of technology tools and characteristics
of student population had
large impacts on the teachers» development
of TPACK, as previously suggested by Koehler and Mishra (2005, 2008) and McCrory (2008).
Today's
technology has already endangered a
large range
of 20th century jobs and will continue to
impact tomorrow's jobs.
This report highlights the key findings
of Wisconsin's 2005
impact study, which found, among other things, that higher test scores correlated with higher staffing levels,
larger and more current collections, greater amounts
of technology resources, longer hours
of operation, and more time spent on instructionally - related student and teacher activities.
This move does not
impact DC Comics» recent relaunch
of a
large number
of titles in several series and the New 52, nor does it affect customers» ability to purchase new digital comics utilizing the digital day - and - date
technology which makes a digital comic available on the same day as a print edition.
With vastly contrasting pixelated art and a futuristic story, 2064: Read Only Memories challenges players not only to solve the mystery to save their friend, but to evaluate their feelings on complicated and incredibly relevant issues about what it means to be human, the dark side
of technology, and how discrimination can have a
larger - scale
impact on the world.
These
large scale prints speak
of our relationship to digital
technologies»
impact on image production, artistic processes and the dissemination
of information.
From the same period, Hans Haacke's Rhinewater Purification Plant demonstrates human
impact on water systems, while Agnes Denes» 2005
large - scale Pyramids
of Conscience monumentalizes humanity's relationship with Hudson River water, New York City tap water and crude oil, all
of which are entombed for contemplation via the «pure
technology»
of the artist's pyramids.
However, if some (or many)
of these efforts have some smoke - and - mirror aspect to them, or if they become the seemingly easy «solution du jour» and allow us to think that we can avoid
larger solutions (fuel efficiency standards; carbon tax, or firm carbon cap combined with a robust and regulated carbon credit trading mechanism; substantial investments in new energy
technologies; energy conservation; etc.), their net
impact can be more damaging than beneficial.
Carbon dioxide removal addresses the root cause
of climate change — high concentrations
of the greenhouse gas in the atmosphere — and generally have well - understood benefits and risks, but current
technologies would take decades to achieve moderate results and be cost - prohibitive at scales
large enough to have a sizeable
impact.
This includes an evaluation
of low - cost methods for undertaking floating - to - floating heavy lift operations, a study to identify cost - effective
technologies and strategies for monitoring and inspection, and another to assess the
impact of larger turbines (up to 15 MW) on floating foundations.
The number
of governments, private corporations, organizations, scientists and
technologies concerned with meeting the challenge
of climate change and global warming have increased beyond expectations in the past decade and continues to create an army
of «green fighters,» like Green Peace, but the
impact on
large numbers
of people have not reached a critical mass to reverse the present warming trends.
CCS
technology for
large scale commercial use is still in the beginning stages; and the economic and environmental
impacts of it remain unclear.
So when I say «energy innovation» policies, I'm not talking about a silver bullet, I'm talking about a suite
of policies from R&D, demonstration, financing, deployment, and market - based that not only develop the clean tech we need, but creates a competitive market for them, and get those
technologies to market quicker than if left alone.My concerns shared in the post are those that ignore the innovation piece and assume, to a point a you do, that price or regs or taxes will have not just an immediate
impact but a
LARGE impact.
In the case
of a
large office, for example, the combination
of green design techniques and clever
technology can not only reduce energy consumption and environmental
impact, but also reduce running costs, create a more pleasant working environment, improve employees» health and productivity, reduce legal liability, and boost property values and rental returns.
Additionally, the
larger company Y has convinced their chosen government representatives to back legislation that will effective block the roll - out
of this
technology indefinitely pending «environmental»
impact studies, etc..
The achievement
of the SE4All objectives will also depend critically on the efforts
of a group
of countries with a relatively
large impact at the global level, while state -
of - the - art
technology transfer to developing economies will be essential.
Wind / solar power in developed nations like Germany and France is economically sound, simply due to the very low discount rates in those countries (discount rate has a very
large impact on the LCOE
of capital intensive
technologies).
Evaluate solar resource variability that
impacts large penetrations
of solar
technologies; Develop standardized and integrating procedures for data bankability; Improve procedures for short - term solar resource forecasting; Advance solar resource modeling procedures based on physical principles.
Installation
of closed - cycle cooling at Indian Point would reduce these
impacts by more than 95 percent and is a feasible
technology used at other
large power plants around the country.
Changes in population, age, income,
technology, relative prices, lifestyle, regulation, governance, and many other aspects
of socioeconomic development will have an
impact on the supply and demand
of economic goods and services that is
large relative to the
impact of climate change.
Rather, mitigation scenarios represent major transformations
of the economy relative to baseline scenarios and, thus, represent
large and highly non-linear changes that will strongly
impact the development
of new energy
technologies on both the supply and demand sides, as well as other relevant
technologies that offset greenhouse gas emissions worldwide.
Externalities may be addressed by either a tax / credit or some other public policy, public ownership and management
of the commons, or privatization
of the commons, or through court actions — each option may have it's own costs — for example, the
large - scale privatization
of the climate system may be impractical with given
technology (analogy with toll roads), and even without that, it has at least an aesthetic cost (nature is supposed to be nature; and psychologically, humans may benifit from some amount
of public space) and perhaps scientific (ie nature — in this context, nature as it is with relatively small
impacts of humankind — is not nature if it is not being itself) costs; there may be inefficiencies in the court system that could be bypassed for issues that are easily addressed with legislation (unless we had a class - action lawsuit on behalf
of all people now until the year).
But that was one
of very few attempts to regulate the issue internationally, which opponents argue is a big missing ingredient given that
large - scale deployment
of technologies in one country could have significant
impacts in others.
Recent improvements in the energy efficiency and environmental
impact of WtE facilities means that the
technology promises to play a
larger role globally in years to come, especially as crowded developing countries start to jump on the bandwagon.
One, they are getting a lot
larger, we know that, but fundamentally that's not about sort
of more seats and chairs, it's really a new business model and it's affecting how law firms invest in
technology, how they think about
technology, how they think about process, how they think about their business models, that's going to be really what that opening session is about is exploring that whole space and talking about how those changes are
impacting all the conversations that will be happening throughout Legalweek in all the different streams and in all the different sessions.
«One could argue persuasively that the
impact of technology has been greater on — and more beneficial to — small firms than
large ones.
Gimmal helps
large - scale consumer packaged goods organizations meet these goals by providing state -
of - the - art
technologies that improve information management at a minimum
impact to day - to - day operations.
Truly transformational
impacts arise when AI is combined with accelerating science and
technology developments in neuroscience,
large scale databases, super-computing hardware, network communications, blockchain distributed ledger systems, digital currencies, the Internet
of Things (IoT), 3D / 4D printing, and cloud computing.
But, though we can begin to see the
impact of artificial intelligence in
large commercial firms,
technology is still really to bite on poorer private client firms — except perhaps in relation to practice management.
The company says that Ella combines Blue's planar magnetic
technology with an on - board amp and
large, high - capacity cabinets to deliver a perfect blend
of accuracy and
impact.
Our
technology consultant resume sample keeps readers» attention by instead showcasing the results
of selected projects, choosing only those with the
largest positive
impact and enterprise - wide influence.