Sentences with phrase «larger multicenter»

He points to research by a Stanford University researcher, Allan K. Mishra, who has studied PRP for years, whose in his most recent published research includes a large multicenter study [8] involving a host of well - respected orthopedic surgeons around the country who followed 230 patients in a double - blind randomized control study [the gold standard for medical research].

A large multicenter study of women attempting TOLAC (n = 33,699) also showed that augmentation or induction of labor was associated with an increased risk of uterine rupture when compared with spontaneous labor (1.4 % for induction with prostaglandins with or without oxytocin, 1.1 % for oxytocin alone, 0.9 % for augmented labor, and 0.4 % for spontaneous labor).

In addition, there was no effect on breastfeeding duration when the pacifier was introduced at 1 month of age.280 A more recent systematic review found that the highest level of evidence (ie, from clinical trials) does not support an adverse relationship between pacifier use and breastfeeding duration or exclusivity.281 The association between shortened duration of breastfeeding and pacifier use in observational studies likely reflects a number of complex factors such as breastfeeding difficulties or intent to wean.281 A large multicenter, randomized controlled trial of 1021 mothers who were highly motivated to breastfeed were assigned to 2 groups: mothers advised to offer a pacifier after 15 days and mothers advised not to offer a pacifier.

A statin drug commonly used to lower cholesterol is not effective in reducing the number and severity of flare ups from chronic obstructive pulmonary disease (COPD), according to the results of a large multicenter clinical trial designed and directed by Gerard J. Criner, MD, Director of Pulmonary and Critical Care Medicine at Temple University Hospital in Philadelphia, PA..

The attendees developed a list of top research priorities and a research agenda for exercise in solid organ transplant, which includes the need to conduct large multicenter intervention studies, standardize measures of physical function in clinical trials, examine the benefits of novel types of exercise, and assess the effects of exercise on measures such as immunity, infection, and cognition.

«If our results are confirmed in a large multicenter trial,» Dutta said, «vitamin D supplementation would provide us with a new tool in the armamentarium of diabetes prevention strategies.»

Imaging decision - making for those with cardiac implantable electronic devices has started to change with publication this year of a large multicenter study called the MagnaSafe Registry study, which showed that non-conditional devices can be safely imaged by MRI, if proper precautions are observed.

Review outcomes and funding rates for contracts (a mechanism often used to fund large multicenter clinical trials) were not included in these analyses.

In patients with metastatic breast cancer, our large multicenter study confirmed that CTC can be used as a prognostic marker and that dynamic early changes during chemotherapy are associated with the treatment outcome (Pierga, Ann Oncol 2012).

The department serves as liaison to and interfaces with internal and external investigators on both small and large multicenter studies to manage and access samples and to coordinate biospecimen collection and processing.

It was a large multicenter clinical study comprising phase I and phase II portions.

Not exact matches

The research team is planning larger, multicenter trials to confirm the role of subglandular ADC analysis in predicting preterm birth, Dr. Masselli said.

The researchers believe that a larger, multicenter study is needed to better define the potential role of focused ultrasound in managing Parkinson's disease.

«This is the first large prospective multicenter study that was specifically constructed to look at the relationship between sleep apnea and a specific cancer,» said lead author Miguel Ángel Martinez - Garcia, MD, PhD, from the Hospital Universitario y Politécnico La Fe, Valencia, Spain.

The study is believed to be the first and largest, multicenter, double - blind, randomized controlled trial of its kind to investigate the use of sublingual immunotherapy against ragweed allergy.

Large, multicenter trials are now the norm for clinical trials.

«Our findings, in a large, multicenter sample of patients, reinforce the known association between OSA and cardiovascular disease,» said researcher Luciano Drager, MD, PhD, of the University of São Paulo School of Medicine in Brazil.

Indeed, research doesn't always support the notion that salt causes high blood pressure: A large, multicenter study known as INTERSALT compared urinary sodium levels — an accurate indicator of prior sodium consumption — with hypertension in more than 10,000 people in 1988 and found no statistically significant association between them.

As the next step for this line of research, the investigators plan to expand to a larger prospective multicenter trial to further investigate the efficacy of the treatment in a larger sample of patients with dry AMD.

In this study, O'Connor and colleagues studied all cases of morphologic induction failure from the large, multicenter Medical Research Council UK ALL 2003 trial, to determine whether end of induction MRD should be used in defining induction failure.

Applications involving contracts (such as used for large, multicenter clinical trials) were not included in these analyses.

Despite the marginal improvements in survival of patients suffering from malignant glioma treated with gene therapy vectors, the clinical trials conducted so far using viral vectors, in particular adenoviral vectors, have proven that the use of adenoviral vectors is a safe therapeutic approach, even in large, multicenter, phase 3 clinical trials.

The largest intervention study on a vegan diet that I know of showed better overall nutrient intake, but calcium was one nutrient that was very low Nutrient intake in the GEICO multicenter trial: the effects of a multicomponent worksite intervention.

In a large, multicenter trial conducted in the United Kingdom, 7 or 10.5 g / d of psyllium was provided to 340 patients with mild to moderate hypercholes - terolemia over 12 weeks (MacMahon and Carless, 1998).