Sentences with phrase «larger ongoing study»

Participants were part of a larger ongoing study examining the cardiovascular effects of binge drinking.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Ongoing projects include studies of gene - environment interactions and adverse pregnancy outcomes, as well as informed medical decision making demonstration projects in Medicaid maternity populations and within HealthWise, the nation's largest source of health information materials distributed through healthcare networks.

The study looked at 90,214 participants in three large, ongoing studies.

Researchers leading a large, ongoing study in women called VOICE that compares PrEP with pills to a vaginal microbicide plan to revaluate the ethics of continuing to use a placebo control group given the new evidence of oral Truvada's powerful impact.

«It is still possible, however, that vitamin D supplementation could have beneficial effects on cardiovascular health via non-blood pressure effects, and ongoing large randomized trials are due to report on this in the next few years,» the study concludes.

The first large U.S. study aimed at resolving an ongoing debate about the best way to treat an early sign of breast cancer will launch later this year under the direction of a Duke Cancer Institute investigator.

A phase II basket study is ongoing to determine whether these early results can be confirmed in a much larger cohort of patients.

Early results from a larger, ongoing study led by environmental health scientist Richard Pilsner at the University of Massachusetts Amherst suggest that phthalate levels in expectant fathers have an effect on couples» reproductive success via epigenetic modifications of sperm DNA.

In this 9 - centre, large ongoing cohort study, researchers evaluated the survival in Caucasian CHB patients with or without cirrhosis who have been receiving ETV or TDF.

HRS, sponsored by the National Institute on Aging, is the largest ongoing national study of adults age 51 and older.

While the research is still ongoing, this latest study represents the largest analysis to date, including over 7,000 tissue samples.

These new findings laid the groundwork for a much larger, ongoing study funded by the Wellcome Trust and involving several UK Universities and Pharmaceutical companies that will seek to replicate the findings and refine the test.

In ongoing studies, the researchers spray influenza virus into the noses of volunteers via a mist, created by an atomizer that only produces particles larger than 10 microns.

The drug has already demonstrated safety in nonhuman primate trials, and the cardiovascular research might even be able to skip ahead to a larger phase II trial based on safety data from the ongoing phase I studies, Leeper suggests.

«Our future field studies will focus on voluntary commitment devices in other health behaviors, such as gym exercise and smoking cessation, which can work in large - scale incentive programs and help people maintain self - control on an ongoing basis.»

An ongoing study conducted at a large metropolitan NICU, however, shows that a little skin - to - skin snuggling between mothers and babies can go a long way toward reducing maternal stress levels.

A larger ongoing phase 3 study (SONAR; ClinicalTrials.gov identifier NCT01858532) will shed more light on the kidney and cardiovascular protective effects of atrasentan.

The star - forming dwarf galaxy in the new study was found during an ongoing, large - scale inventory of the heavens, the Sloan Digital Sky Survey, which revealed it as a possible point of interest.

The NYGC and its founding member institutions are conducting additional studies involving Watson to help accelerate the discovery of potentially actionable sequence variants in various types of cancer, including an ongoing study that involves DNA and RNA from a larger cohort of glioblastoma patients, and a study of 200 patients with different types of cancer.

«We're looking forward to longer - term results to come in the next five years from various ongoing observational studies,» Dr. Arterburn said: The Utah Obesity Study, the Michigan Bariatric Surgery Collaborative, and large cohorts from Veterans Affairs health system and the HMO Research Network (including Group Health) and should yield important long - term information comparing the efficacy, safety, and costs of surgical and non-surgical care for severe obesity.

Dr Shepherd is additionally co-convenor of an extensive pan-African network of crop scientists and virologists that is carrying out the world's largest ongoing plant pathogenic virus diversity studies.

We study common, low frequency and rare variants [1] in an ancestrally diverse population of > 40,000 individuals recruited from throughout New York City through the Mount Sinai's ongoing BioMe EMR - linked Biobank, [2] in the large - scale UK Biobank (n = 500,000), and [3] in a unique discordant - sib family study.

Larger studies are now needed to assess the potential role of this technology in the ongoing care of patients with GLILD and it is likely that it will be increasingly used in a wider range of inflammatory disorders.

To complement ongoing positional cloning efforts, we have undertaken a large - scale candidate gene association study.

February 27, 2002 Human and fly studies tally good and bad mutations, stress ongoing role of natural selection Natural selection plays a much larger role in molecular evolution than suspected.

Two large - scale trials, each involving upwards of 20,000 people, are still ongoing, said Manson, who is leading one of the studies.

Researchers hope that if the ongoing preliminary studies prove the safety and effectiveness of these drugs for certain treatments, the government will step in to fund larger trials.

The participants were all drawn from a larger, ongoing study known as Whitehall II that began in 1985.

The new study — the first of its kind to assess people as young as 45 — is part of a larger, ongoing study known as Whitehall II.

In the study, published this week in the Archives of Internal Medicine, Sieri and her colleagues analyzed data from a large, ongoing study of nutrition and cancer risk.

The large, ongoing French E3N study is providing valuable safety data for users of bioidentical hormones, most recently on estrogen, progesterone and the risk of stroke.

In 2010, The University of Texas MD Anderson Cancer Center received more than $ 4.5 million — one of the largest yoga - related grants ever — from the National Institutes of Health's National Cancer Institute to support an ongoing study of the efficacy of yoga as part of a treatment program for women with breast cancer.

This is a continuation of the large, ongoing French study of HRT known as the E3N Cohort Study, which has already published results twice, each time more clearly and definitively confirming that progestins increase breast cancer risk significantly, while progesterone doesstudy of HRT known as the E3N Cohort Study, which has already published results twice, each time more clearly and definitively confirming that progestins increase breast cancer risk significantly, while progesterone doesStudy, which has already published results twice, each time more clearly and definitively confirming that progestins increase breast cancer risk significantly, while progesterone does not.

Most, though not all, of his research is based on two large ongoing cohort studies at Harvard: the Nurses Health Study and the Health Professionals Follow - Up Study.

A study conducted in 2000 examined the relationship between the HEI and the risk of major chronic disease (cardiovascular disease and cancer), using the large cohorts in two ongoing studies at Harvard (nurses and health professionals).

My colleagues and I recently conducted a large survey study as part of our ongoing efforts to understand the writing lives of college students in order to better support student learning.

A large well - controlled study in the UK found that parents» reports of their child being bullied at school predicted increased risk of ongoing mental health problems for children several years later (Arseneault et al, 2008).

An ongoing communication with an enthusiastic Social Studies teacher in a large Midwestern school district ended abruptly when she emailed me: «Due to NCLB corrective action our district will need to channel our professional development time and funds toward this goal.

Researchers are currently recruiting dogs for this ongoing study — both those with mass lesions, as well as some without any known or palpable masses; for example, they may have inflammatory large bowel disease.

The gestural abstraction of Yayoi Kusama's ongoing series of Infinity Net paintings and her important large - scale accumulation sculpture Prisoner's Door provides a formal counterpoint to the geometric abstraction of Conrad Shawcross's Perimeter Studies sequence and Plosion sculpture, which take theories of cosmic expansion and contraction as their starting point.

on the subversion of opacity is the third iteration of the large - scale curatorial project by Italian curator Alessandro Facente entitled About Practice, a series of group shows about ongoing studies and theories on the artist's practice in relation to reality.

Heading Southwest [About Practice # 2] is part of the large - scale curatorial project by Italian curator Alessandro Facente entitled About Practice, a series of group shows about ongoing studies and theories on the artist's practice in relation to reality.

«Unreasonable Sized Paintings» (a term neither limited to unorthodox variations in canvas shape nor monumentally sized paintings), showing at SVA Chelsea Gallery, refers to the work of painters who, during occasional unpremeditated episodes, feel compelled to make paintings that are neither specific studies of larger or smaller paintings nor parts of particular ongoing series, but rather the byproduct of pure pleasure or the release of spontaneous thoughts that need to be concretized without limitations.

A 2000 graduate of the Whitney Museum Independent Study Program, Geyer works with photography, video and performance, using both fiction and documentary strategies in order to address larger concepts such as national identity, gender, and class in the context of the ongoing re-adjustment of cultural meanings and social memories.

As our ongoing Energy Challenge series and plenty of independent studies have made clear, the country and world are still not engaged seriously in advancing non-polluting energy technologies, from solar cells to the elusive notion of capturing carbon dioxide from power plants at a large scale and stashing it somewhere.

I don't know, I'm not part of that conspiracy, and I see a lot of assertions on here and elsewhere by people who imply they are smart, or at least smart enough to know more on this issue than the climate scientists who actually professionally study it, who throw around large highfalutin science terms, but that repeatedly misconstrue the basic climate change issue itself, conflate the process of science with Climate Change refutation, seem to have an extensively poor understanding of the issue, and take small select bits of data as part of the ongoing total picture of increasing overall corroboration, to falsely equate that with a flaw in Climate Change theory itself, or as a referendum on it.

The most recent study is part of ongoing effort to create an OCSI 2.0 — an instrument that like 1.0 «disentangles» knoweldge & identity but that can distinguish levels of knowledge in a more fine grained way across larger portion of popuolation & w / regard to more interesting elements of climate science.

The UMTRI / Toyota Teen Driver Distraction Study, the largest scientific survey of its kind, also found that texting while driving remains commonplace among teens, despite ongoing, nationwide efforts to educate drivers on the significant risks associated with these behaviors.

This study of intervention effects is part of a larger ongoing longitudinal study of all consenting fifth - grade students in 18 public schools serving high - crime areas of Seattle, Wash..