Sentences with phrase «larger precursor protein»

On page 735, molecular biologists describe a new candidate for b - secretase, an elusive enzyme that is needed to free one end of b - amyloid from its larger precursor protein.

This protein is part of the enzymatic engine that churns out amyloid beta — a key molecular culprit in Alzheimer's disease — by snipping it out of a larger precursor protein called APP.

For example, antibody studies showed that it is located in the Golgi apparatus and endosomes, two structures within cells in which b - amyloid is known to be cleaved from its large precursor protein.