Sentences with phrase «larger scale trial»

It eliminates expensive, larger scale trial and error.

This is a very promising finding that provides an excellent basis for future larger scale trials using the intervention in very early development.»

Moving forward, the NUS team intends to carry out larger scale trials to establish the full potential performance of sand for impact resistance.

Several large scale trials were launched with this hope.

So overall it looks like you may be correct in identifying that honey has advantages over sugar, but we will need a few more larger scale trials over a longer period to see if this can really have long term health benefits, rather than short term effects.

Not exact matches

While the new mid-stage study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even for the sickest patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale in the developing world.

Just this month, as part of the first large - scale clinical trial of its kind, researchers working in rural India found that newborns who were given a synbiotic were at a substantially lower risk of developing sepsis, a potentially fatal condition characterized by severe infection.

Some small studies have suggested that synbiotics could provide benefits to a range of other conditions influenced by the gut microbiome as well, including obesity, diabetes, and non-alcoholic fatty liver disease, but larger - scale clinical trials focusing on each of those conditions are needed.

Grail, a year - old, Menlo Park, Ca. - based early cancer screening startup that spun out of the DNA - sequencing giant Illumina is reportedly looking to raise up to $ 1.7 billion in fresh funding to launch a large - scale clinical trial.

The results, which mirror those of similar, small - scale studies of the illegal drug in recent years, come as MDMA is about to enter larger, Phase 3 trials this summer.

If large - scale trials can replicate safety and efficacy results, the drug could be approved for legal use by 2021.

«It's often very difficult to go to large - scale factory trials,» Andersen said.

Our highly skilled technicians combined with our laboratory - scale processing equipment reduce the need for large plant trials and accelerates the development of your product and speed to market distribution.

He contributes to other large - scale clinical trials including SAVE (evaluating whether treatment of obstructive sleep apnoea with continuous positive airways pressure can reduce the incidence of serious CV events in patients with established CVD), and CREDENCE, a randomised, double - blind, placebo - controlled trial assessing whether canagliflozin can slow the progression of diabetic nephropathy in patients with type 2 diabetes.

The third program, developed in Australia and employed in a large - scale trial at the University of South Carolina, is called the Triple P - Positive Parenting Program.

Conducted by Ron Prinz of the University of South Carolina, this first large - scale American trial of Triple P directly addressed, and affirmed, the success of the program in reducing substantiated child maltreatment, out - of - home placements of maltreated children, and maltreatment injuries.

Despite aromatherapy's long history of use, there is still a lack of large - scale clinical trials exploring the effects of aromatherapy on anxiety.

«Protein in breast milk reduces infection risk in premature infants: Study shows need for large - scale trial of lactoferrin's role in immune system development.»

«Our results justify the need for a large - scale trial of lactoferrin, as well as its counterpart derived from cow milk, bovine lactoferrin.»

The Department for Work and Pensions (DWP) quietly published a large - scale trial of the scheme last year.

And in several large - scale pharmaceutical trials, drugs specifically designed to elevate HDL had no effect on heart disease risk.

In light of the results, the CNIO Breast Cancer Clinical Research Unit has already launched a large - scale Phase II Clinical Trial to validate the results in a large group of patients.

Several large - scale trials are under way to assess how well cannabis treats these conditions.

But billions of dollars have poured into large - scale clinical trials of amyloid - lowering therapies that so far have failed.

Small - scale studies have suggested that the nets do work, but there haven't been any large - scale clinical trials.

An NIH - backed vaccine is among several heading for human trials, but the timeline for large - scale deployment remains murky

This year, Rocke hopes to conduct larger - scale field trials to determine the levels of immunity required for success in a mass vaccination.

As Scientific American reported earlier this year, more than half of the current cancer clinical trials do incorporate some form of immunotherapy but still oncologists are often only in the early stages of understanding how to use such treatment on a larger scale.

That's because a trial like this one is almost without precedent in modern medical research: It involves giving children a vaccine that is almost certain not to benefit them, and that might harm them, all to protect other children from an unlikely scenario — a large - scale anthrax attack.

It is hard to see how we might find out the truth without large - scale and long - term trials.

And scientists who conduct human challenge studies, which typically involve a few dozen participants, say they have critical benefits: In addition to saving time and money, they can reveal harm caused by a potential drug or vaccine before it enters large - scale human efficacy trials.

A panel of scientists said there was no scientific justification for this large - scale trial of a single product and the money has now been handed to the National Institutes of Health to compare several vaccines instead.

But vaccines that only contained HIV's surface protein looked lackluster in animal and test tube studies, and then proved worthless in large - scale clinical trials.

This vaccine has been at the heart of a controversy in the US after Congress awarded the defence department $ 20 million to test it in large - scale trials in America as an immune therapy for HIV - positive people.

Researchers recommend large - scale clinical trials to confirm that nighttime fasting results in favorable changes to biomarkers of glycemic control and breast cancer risk.

It was originally designed to advance to a Phase 3 trial among 28,000 volunteers but was scaled back because the decline in new Ebola cases made it impossible to conduct the larger study.

In 2013, Dr. Schwartz and his colleagues launched the first large - scale, Phase II, randomized trial of selumetinib.

«We don't know what exposure is leading to this susceptibility to dietary glutamate, but this pilot study suggests the need for a large - scale clinical trial, since dietary change could be an effective low - cost treatment option for developing countries.»

Becoming compliant with the proposed ruling could, according to one HHS official, drive up the cost of doing large - scale trials or surveys because of the extra work involved in ensuring that projects meet the standards required.

Many scientists believe that small or medium scale field trials may be needed to understand the risks of large - scale geoengineering projects.

Wolfe acknowledges, however, that we won't know what the long - term safety issues are until a large - scale human trial is conducted, which researchers hope to begin in the next three years.

«However, large - scale, randomized clinical trials will provide more definitive evidence regarding these risks in the coming years.»

We also have a large - scale biologics manufacturing facility in Rensselaer, New York, where we produce commercial and investigational products for clinical trials, and a satellite office in Basking Ridge, New Jersey.

The controversy came to a head in March when the National Institutes of Health issued a notice of a competition soliciting participation in a large - scale clinical trial to evaluate the effectiveness of fetal surgery as a treatment for spina bifida.

One malaria vaccine is in large - scale trials.

For example, this could support large - scale epidemiologic studies or remote pharmacological trials,» said senior and corresponding author David L. Kaplan, Ph.D., Stern Family Professor in the Department of Biomedical Engineering at Tufts School of Engineering.

Graham looked to the Internet for treatment options and came across Duke University oncologist Keith Sullivan, who was comparing standard chemotherapy and stem cell therapy as part of a large - scale clinical trial for scleroderma.

Larger scale clinical trials are needed to clarify the best approach to cannabinoid therapy in obstructive sleep apnea, the authors said.

The researchers caution that the reliable detection of small to moderate risks and benefits of drug therapies requires cogent data from large - scale randomized trials designed a priori to test the hypothesis.

While a postdoctoral fellow at the Naval Medical Research Institute in Bethesda, he developed a system for large - scale efficient culture of lymphocytes that has proved to be the foundation for over 35 early phase clinical trials of adoptive immunotherapy.