Sentences with phrase «larger trials expectedanchor»

Second, while the small sample size that accompanies an open trial is a limitation, our findings were statistically significant, with large effect sizes that are comparable to larger trials of standard PCIT.

Asymmetry might be due to publication bias, but might also reflect a relationship between trial size and effect size such as when larger trials have lower compliance, and compliance is positively related to effect size.

Definitive larger trials will therefore be required to establish whether the results of the present meta - analysis are reliable.

Further UK trials with long term follow up will also be needed, in particular larger trials, including all families, which use outcome measures capable of measuring change at the positive end of the mental health spectrum.

Larger trials that can investigate the role of baseline relationship functioning on PTSD, and relationship satisfaction outcomes are needed to facilitate treatment - matching efforts and to determine the boundaries of CBCT's efficacy.

This presentation will share results from this qualitative interview and discuss implications for future groups and larger trials being run in this growing field.

Researchers hope that if the ongoing preliminary studies prove the safety and effectiveness of these drugs for certain treatments, the government will step in to fund larger trials.

Taking triple the daily recommendation didn't lower risk in older women, but larger trials are underway

The authors concluded that these meta - analyses support the need for further controlled, larger trials to assess the clinical efficacy of rTMS on negative and positive symptoms of schizophrenia, while suggesting the need for exploration for alternative stimulation protocols.

Larger trials involving aducanumab will be carried out and will run until 2022.

If this holds up over the next few years of larger trials it should become very clear as to the degree to which amyloid - β is or is not in fact the primary cause of pathology in Alzheimer's disease.

Whitehead and the other researchers said that in the case of dengue, the testing was warranted because they knew that the vaccine appeared to be effective at preventing dengue 1, 3 and 4 viruses through previous testing but needed to learn more about its impact on dengue 2 before proceeding to larger trials that could take three to 10 years and cost tens of millions of dollars.

In addition, replication of positive results in larger trials is costly, and NIMH is constrained by limited funding and a budget that has lagged well behind inflation over the last decade.

Additional limitations to the traditional approach include: costly failures to replicate positive results in larger trials; difficulty in determining the reasons for negative results; low yield in terms of identifying disease or intervention mechanisms due to an exclusive focus on symptom change and clinical endpoints; and, the expensive and very lengthy practice of first establishing multi-component psychosocial treatments followed by years of «unpacking» studies.

The team is planning larger trials and other experiments to better understand how the drug might be working.

Spigelman cautions, however, that larger trials are needed to confirm the effectiveness of both therapies and for them to be approved for global use.

The results are encouraging and we now need larger trials to understand whether the effects we saw in this study translate into long - term benefits, and to study how psilocybin compares to other current treatments.»

In any case, while the results need replication in larger trials, they point to a potential method to target drug therapy for PTSD patients.

But this won't become clear until the results from larger trials are in.

The small, phase 1 trial enrolled 11 patients and found that side - effects were similar in this population as previously reported in larger trials of enzalutamide against prostate cancer.

Published early online in CANCER, a peer - reviewed journal of the American Cancer Society, the results indicate that larger trials are warranted to determine whether the drug should become part of standard therapy for women with the disease.

The researchers are also calling for caution until larger trials have taken place.

However, prior to changing practice, larger trials are needed to determine whether improvement in these surrogate measures will translate into fracture reduction for vulnerable elderly persons,» the study concludes.

Burt is now organizing larger trials for both diseases as well as other autoimmune disorders.

Larger trials and longer follow - up will be needed to confirm the results, he added.

The company is starting larger trials to see if the vaccine can actually protect people from getting sick.

Several compounds that boost glutamate signalling in the brain have reached early clinical trials, although it is too soon to say if they will pass the larger trials needed to prove their worth.

Kaptchuk agrees and wants to run some larger trials to get a better picture of the effect.

The researchers have now treated a third individual and are preparing for larger trials in Europe and the U.S.

If confirmed by larger trials, the finding could lead to a diagnostic test that will help cardiologists identify and treat high - risk patients.

It is worth noting at this point that this is not yet another case of a drug entering the market only to be withdrawn later because of lack of efficacy or even adverse reactions which could have been noticed with longer or larger trials.

We need much larger trials, on more diverse populations, before we can start to make a difference to how patients are treated.»

Larger trials with stricter safety measures have demonstrated that with a cautious protocol, breech birth can be conducted safely in appropriately supported obstetrical units.

If myelofibrosis trial results are consistent with previous observations, the healthcare behemoth will help fund larger trials in order to support New Drug Applications.

The program will involve clinical trials testing for safety in humans, followed by a larger trial using non-human primates exposed to Ebola.

Physicians prescribe medical foods, but they are less tightly regulated than drugs and normally don't require large trials, which means the stuff could be on the market as soon as this year.

The company then analyzes the different varieties, and the varieties that are successful will be planted in a larger trial consisting of several acres, and tested in different growing areas.

One large trial in patients with heart disease showe d that supplementing with 1 gram of omega - 3 per day reduced their risk of death by 20 %.

It doesn't indicate if this is going to go to the public, which is something we would obviously need in order to officially review this, but it does say that a larger trial is being planned for this.

Another perennial top - finisher, the state's largest trial lawyers» group was involved in issues in 2016 ranging from the Scaffold Law to the expansion of ride - hailing.

A large trial of supplements is due to finish in July, but a smaller one, in which 36 people took a pill containing all three pigments every day for six months, has already yielded positive results.

But this study showed that acupuncture added nothing beyond medication,» said Legro, who noted that this large trial is one of the highest quality acupuncture trials to address fertility outcomes.

Advanced Cell Technology is now planning a larger trial, first in 100 people with Stargardt's, then in people with macular degeneration.

Several large trials of amyloid - based therapies are underway in groups of people more carefully selected to be at high risk for Alzheimer's.

We will know more later this year, when the results from a large trial that addresses exactly this question will be published.

Next up: a larger trial in hundreds of patients to see if lowering mutant Htt protein slows progression of the disease, then a trial in healthy people who carry the mutant HTT gene to see if antisense treatments could prevent Huntington's altogether.

«Although it should be validated with a larger trial with more robust clinical endpoints,» he added, «given the pharmacoeconomic implications, these data warrant consideration by prescribers, payers and patients.»

«To the best of our knowledge, this is the largest trial of a perioperative, cardiac output - guided hemodynamic therapy algorithm to date.

Stanford researchers are in the middle of a larger trial (which will involve up to 156 patients) that might provide more definitive answers.

«These results support advancing to a larger trial capable of addressing whether inosine might fill the critical unmet need for disease - modifying treatment.