Not exact matches
Beset by labour disputes and an inability to adapt to
changing markets, the
country's
largest firms merged
in 1968 as British Leyland before being nationalized
in 1975.
In the longer term the EU wants to change existing taxation rights to make sure digital firms with large operations but no physical presence in a given country pay taxes there instead of being allowed to reroute their profits to low - tax jurisdiction
In the longer term the EU wants to
change existing taxation rights to make sure digital firms with
large operations but no physical presence
in a given country pay taxes there instead of being allowed to reroute their profits to low - tax jurisdiction
in a given
country pay taxes there instead of being allowed to reroute their profits to low - tax jurisdictions.
(A Fortune magazine piece last year covered how GoDaddy worked to
change the tone of its racy, sometimes sexist, ads
in order to better appeal to women, who represent a
large swath of the
country's small business owners.)
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth
in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures
in European
countries that may increase the amount of discount required on Gilead's products; an increase
in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a
larger than anticipated shift
in payer mix to more highly discounted payer segments and geographic regions and decreases
in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations
in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations
in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials
in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations
in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates
in the timelines currently anticipated; Gilead's ability to receive regulatory approvals
in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta
in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to
changes in its stock price, corporate or other market conditions; fluctuations
in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time
in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
The
country has the world's third -
largest economy, yet this may
change over the next few decades as its population — the fastest aging
in the world — plummets from 126 million
in 2015 to 87 million
in 2060.
Incorporating three metrics is a balanced and robust approach: While
country - adjusted and industry - adjusted returns risk being skewed toward smaller companies (it's easier to get
large returns if you start from a small base), the
change in market capitalization is skewed toward
larger companies.
China's slow move to a market - based system, which has been facilitated by
In a
country as
large and economically important as China,
change should be approached over the long - term.
The
larger objective of this subtle but far - reaching
change is to encourage greater foreign investments
in services, and to position India as a hub for exporting services to third -
country markets.
These concerns might recently have been exacerbated by
changes in the pattern of corporate financing:
in countries in which the swap spread has increased the most — the US and UK — growth
in private sector bond issuance has been relatively
large, while net equity issuance has been low (or even negative as
in the United States).
Brazil, South America's
largest country and Canada's leading trading partner
in the region, is tottering under corruption and governmental
changes.
The
largest costs of climate
change are disproportionately borne by poor
countries, especially
in Africa and South - Southeast Asia.
Unless it was meant for us as a new system to drop Republican systems for the Royalist systems that are taking place now that Jordan and Morocco both Royelists are planed to join GCC as one with a
change to the name of the GCC since the Royalist empire will be extending to
countries outer of the Arabian Gulf Countries... What ever it is all we need is freedom of rights, justice, peace, equality and to live in prosperity... Egypt is not in the heart of Egyptions only but as well in the heart of every Arabic nation, Egyptions were our teachers in our schools and Egypt was the university of our Yemeni students... Egypt was the source of islamic educations, Egypt was the face of all arts, books, papers, TV plays and movies to all of Arabian speaking countries... Egypt is our Arabian Icon so please please other nations are becoming larger and stronger in the area on your account as a living icon for the Arabian Unity what ever our faiths or beliefs are we are brothers in blood, culture and language, God Bless to
countries outer of the Arabian Gulf
Countries... What ever it is all we need is freedom of rights, justice, peace, equality and to live in prosperity... Egypt is not in the heart of Egyptions only but as well in the heart of every Arabic nation, Egyptions were our teachers in our schools and Egypt was the university of our Yemeni students... Egypt was the source of islamic educations, Egypt was the face of all arts, books, papers, TV plays and movies to all of Arabian speaking countries... Egypt is our Arabian Icon so please please other nations are becoming larger and stronger in the area on your account as a living icon for the Arabian Unity what ever our faiths or beliefs are we are brothers in blood, culture and language, God Bless to
Countries... What ever it is all we need is freedom of rights, justice, peace, equality and to live
in prosperity... Egypt is not
in the heart of Egyptions only but as well
in the heart of every Arabic nation, Egyptions were our teachers
in our schools and Egypt was the university of our Yemeni students... Egypt was the source of islamic educations, Egypt was the face of all arts, books, papers, TV plays and movies to all of Arabian speaking
countries... Egypt is our Arabian Icon so please please other nations are becoming larger and stronger in the area on your account as a living icon for the Arabian Unity what ever our faiths or beliefs are we are brothers in blood, culture and language, God Bless to
countries... Egypt is our Arabian Icon so please please other nations are becoming
larger and stronger
in the area on your account as a living icon for the Arabian Unity what ever our faiths or beliefs are we are brothers
in blood, culture and language, God Bless to All.Amen.
My family, for generations, has had a front row seat to the
change and transition Dearborn has gone through to where it is now the
largest Arab American community
in the
country.
Australia had a government
change just before the conference, whereupon the new prime minister, Kevin Rudd, immediately signed on to the Kyoto treaty, committing his
country to
large cuts
in CO2 emissions.
At the same time, they hedged a
large proportion of their capital from
changes in Brazil's economic situation by taking it out of the
country en masse.
It is currently the third -
largest barbecue franchise
in the
country, but Losacco hopes its
changes will boost it up the ranks.
Mr Helou — who is
in China with 1000 other business leaders who are joining Mr Turnbull on what has been dubbed as Australia's
largest ever trade mission to the
country — said he didn't expect the
changes to «materially» hit Murray Goulburn's overall sales into China.
At 23,000 square feet, Mastros Beverly Hills is one of the
largest and busiest restaurants
in the
country, with a 700 bottle wine list that
changes often.
Although, with the availability of
larger variants, the potato chips and potato based snacks dominate the market, the market trends are
changing quickly from traditional snacks to innovative and healthy packaged snacks with regional flavours gaining more popularity
in the
country.
According to those officials present, despite the fact that Houston is the seventh
largest school district
in the
country and therefore a major consumer of milk, the profit margins for dairies supplying schools (as opposed to private entities) is extremely low and would be wiped out by the manufacturing costs associated with making such
changes.
The required provision of baby
changing facilities was a
large step towards making public places more accessible for parents and
in many
countries there are now laws
in place to protect the rights of a breastfeeding mother when feeding her child
in public.
There are
large and small
changes happening
in different parts of the
country, but it's not consistent.
Certainly, he had inherited the former Prime Minister's eagerness for America to be involved
in other nations» affairs (something which is anathema to the old left who see that
country as a bullish, neo-colonial world policeman), saying to an American who queried what was wrong with U.S. disengagement that it was very concerning because only America has the financial resources and will power to cause
large, lasting
change in the world.
Whether one wants public support for the media or not is a political question (and one all developed democracies have answered
in the affirmative
in the twentieth century), but as people's media habits and the economics of the industry
change, effective intervention probably ought to be built around the «information» part of the sentence quoted above rather than the «several
large sheets» part (just as «public service broadcasters» have
in many
countries sought to redefine themselves as «public service media organizations» to emphasize their cross-platform ambitions).
At the end of this government's second full year, the same is happening again
in the aftermath of another of the Lib Dems» doomed attempts to
change the constitution, to the yawning indifference of the
country at
large.
It warned: «To preserve the United Kingdom's strong fiscal credibility, any
changes in spending should be part of a multi-year plan focused on further reducing the
country's
large structural fiscal deficit when the economy is stronger.»
His management innovations and game -
changing philosophy had been adopted at least
in part by many other
large police forces across the
country.
«The Governor has led the nation
in combating climate
change from banning fracking to one of the most aggressive clean energy standards
in the
country to closing down dangerous Indian Point to the single
largest procurement of renewable energy
in our nation's history and the first multi-state cap and trade system to lower carbon pollution,» said Cuomo campaign spokeswoman Abbey Fashouer.
The former Vice President, while maintaining that the future of the
country is bright
in view of anticipated
changes in all aspects of the life of the nation, appealed to groups «that are aggrieved
in one way or the other and espousing separatist sentiments, to drop their agitation and take advantage of the improving political climate
in the
country, to seek accommodation
in the
larger united national community that is fast unfolding.»
There is still time for Corbyn's supporters to pull back from the edge, reject the seductive embrace of false consciousness paranoia and conspiracy theory, and focus on
changing the minds of real people
in the
country at
large.
The city school system — the
largest of its kind
in the
country — is on the verge of dramatic
change, and Gov. Cuomo has bet his second term on an aggressive campaign to transform a system he claims has failed more than 250,000 students over the past decade while state bureaucrats twiddled their thumbs.
The «#Ubermadness» ad points out Buffalo is the
largest city
in the
country without ride - hailing and urges viewers to tell state lawmakers they want that to
change.
«Marshallese people have been put into an unfortunate position where the
changes in the
country are so
large that their traditional knowledge isn't sufficient to understand them,» he says.
In an attempt to resolve a sticking point between the U.S. and China, Indian negotiators have proposed monitoring the emissions responsible for climate
change from all
large countries
Prof Guan said: «
In recent years, many researchers have proposed that consumption - based accounting be applied to re-allocate the responsibilities of mitigating climate
change because of the
large net emission flows from developing
countries to developed
countries.
«
In many of the specifics of the way people view climate change — for instance, seeing it as a moral issue and understanding that climate change is going to hurt people in developing countries and the world's poor the most — we saw really large shifts.&raqu
In many of the specifics of the way people view climate
change — for instance, seeing it as a moral issue and understanding that climate
change is going to hurt people
in developing countries and the world's poor the most — we saw really large shifts.&raqu
in developing
countries and the world's poor the most — we saw really
large shifts.»
«A Harper loss will send a strong signal, ahead of Paris and to Republicans
in the U.S., that climate inaction is increasingly becoming a losing political strategy even
in developed
countries with
large fossil fuel resources,» said Paul Bledsoe, a former Clinton White House climate
change official.
WHILE Australia's new carbon tax, announced last week, is a step
in the right direction it is unlikely to
change the
country's status as the
largest per - capita emitter of greenhouse gases
in the developed world.
Given the
country's status of being the
largest greenhouse gas emitter
in the world, Greenpeace says, a tiny drop
in China's carbon emissions could translate into a big
change in the international stage.
The Native American Graves Protection and Repatriation Act of 1990, and legislation like it
in other
countries with
large indigenous populations, is
changing the relationship between archaeologists and the people whose ancestors we study.
The new study is one of the first to monitor recent
large - scale glacier
change in Bolivia, to better understand how receding glaciers could affect communities
in the
country.
In 2007, the American Physical Society, the
country's
largest organization of physicists, adopted a strong statement on climate
change that said «The evidence is incontrovertible: Global warming is occurring.»
It could be an idea for a
large - scale project like The Cancer Genome Atlas, a multiyear effort that involved researchers from institutions across the
country working collaboratively to catalogue all of the
changes to DNA and molecules
in more than 30 different cancer types.
Reckien's team, funded by the European Science Foundation COST Action TU0902, studied the response to climate
change issues of 200
large and medium - sized cities
in eleven European
countries.
Often called the Third Pole due to how much ice and snow accumulates there, the Himalayas and Tibetan Plateau are the source of major rivers
in nearby
countries and
changes to them can affect the
largest populations
in China and India.
Even if we are
in a part of the
country that doesn't have
large transitions
in the weather, we can still see the
changes happening all around us.
A dedicated champion of culture
change, Working Mother is the
largest multimedia company
in the
country focused on diversity and the advancement of women.
Interracial us understand when to begin dating and the game has
changed Google removes one of the worlds
largest gay dating apps from its online store
in Indonesia amid
countrys crackdown on LGBT.
When a typical teenager discovers her family is moving from a
large city to a small town
in the
country, there are plenty of
changes she's planning on... but battling swarms of murderous insects isn't one of them.
Most of the film is set
in 1971,
in Harrisville, Rhode Island, where a family of seven — parents Roger (Livingston, Game
Change) and Carolyn (Taylor, Public Enemies), and their five young daughters — have just moved
in to their
large country 18th - century abode.