Sentences with phrase «largest controlled studies»

It was one of the largest controlled studies to date analyzing the impact of yoga on fertility.

However, larger controlled studies with long - term follow - up are required to demonstrate whether the favorable properties of DFS translate into improved event - free survival in patients with coronary artery disease.»

Replication of these findings with larger controlled studies will be necessary.

Other studies that measured actual frequency, volume and gas content of flatulence, in larger controlled study groups, show that flatulence is correlated to fibre intake.

Not exact matches

Page said that even in a best case scenario, a male birth control pill for consumers is still between five and 10 years away, since much larger - scale studies need to be done before the FDA would give a seal of approval.

And yet the largest observational study — again we don't have controlled experiments — found that childhood swearing is largely innocuous.

Unlike a similar study last year that found that women chiefs make more than men, this one had a far larger sample and controlled for «chief executives» tenure, characteristics of the firms (size, performance and risk), and the size and independence of the boards.»

Theres a old football saying that if you have the three best QBs in the entire country, you do nt really have 1 and if Urban Meyer is going to control his programs he better spend a summer studying Charlie Weisses playbook on how to manage large Eggos.

The most recent findings of the Belarus study (an excellent, large scale, randomized, first world study) were recently published and show that 11 year - olds have a 17 % GREATER chance of being obese or overweight if they were in the breastfeeding group than in the control group.

A larger study, with randomization to intervention and control groups might help define whether changes were attributable to the intervention, to differences at baseline, or to other influences.

While I agree that much of the research out there for PRP is less than desirable, I think it important to cite to some studies as a counterpoint which do have large numbers, platelet concentrations and control groups.

He points to research by a Stanford University researcher, Allan K. Mishra, who has studied PRP for years, whose in his most recent published research includes a large multicenter study [8] involving a host of well - respected orthopedic surgeons around the country who followed 230 patients in a double - blind randomized control study [the gold standard for medical research].

The strengths of the study include the ability to compare outcomes by the woman's planned place of birth at the start of care in labour, the high participation of midwifery units and trusts in England, the large sample size and statistical power to detect clinically important differences in adverse perinatal outcomes, the minimisation of selection bias through achievement of a high response rate and absence of self selection bias due to non-consent, the ability to compare groups that were similar in terms of identified clinical risk (according to current clinical guidelines) and to further increase the comparability of the groups by conducting an additional analysis restricted to women with no complicating conditions identified at the start of care in labour, and the ability to control for several important potential confounders.

Much of the evidence against BPA comes from large population studies rather than controlled clinical trials.

One study finds an association with disease x, but not y or z, another finds one with y but not x. None of these studies are able to fully control for the critically important confounding variable of maternal health, and none of the decent quality ones have demonstrated a large difference in risk.

More recently, Lucas and Cole, 19 in a large, prospective, controlled study reported a lower incidence of necrotizing enterocolitis among VLBW infants fed human milk compared with formula - fed infants.

This study is still the largest randomized control trial done to date on HFA.

It seems as if another study with a larger sample size is warranted — in addition to a study that has a control group in which parents refrain from giving their infants yogurt.

Some of these studies involved large representative samples from the United States; 2 some studies controlled for potential confounders, such as parental stress3 and socioeconomic status; 4 and some studies examined the potential of parental reasoning to moderate the association between physical punishment and child aggression.5 Virtually without exception, these studies found that physical punishment was associated with higher levels of aggression against parents, siblings, peers and spouses.

Physical punishment is associated with a range of mental health problems in children, youth and adults, including depression, unhappiness, anxiety, feelings of hopelessness, use of drugs and alcohol, and general psychological maladjustment.26 — 29 These relationships may be mediated by disruptions in parent — child attachment resulting from pain inflicted by a caregiver, 30,31 by increased levels of cortisol32 or by chemical disruption of the brain's mechanism for regulating stress.33 Researchers are also finding that physical punishment is linked to slower cognitive development and adversely affects academic achievement.34 These findings come from large longitudinal studies that control for a wide range of potential confounders.35 Intriguing results are now emerging from neuroimaging studies, which suggest that physical punishment may reduce the volume of the brain's grey matter in areas associated with performance on the Wechsler Adult Intelligence Scale, third edition (WAIS - III).36 In addition, physical punishment can cause alterations in the dopaminergic regions associated with vulnerability to the abuse of drugs and alcohol.37

In addition, there was no effect on breastfeeding duration when the pacifier was introduced at 1 month of age.280 A more recent systematic review found that the highest level of evidence (ie, from clinical trials) does not support an adverse relationship between pacifier use and breastfeeding duration or exclusivity.281 The association between shortened duration of breastfeeding and pacifier use in observational studies likely reflects a number of complex factors such as breastfeeding difficulties or intent to wean.281 A large multicenter, randomized controlled trial of 1021 mothers who were highly motivated to breastfeed were assigned to 2 groups: mothers advised to offer a pacifier after 15 days and mothers advised not to offer a pacifier.

The German Study of Sudden Infant Death, the largest and most recent case - control study of SIDS, found that exclusive breastfeeding at 1 month of age halved the risk of SIDS (adjusted OR: 0.48 [95 % CI: 0.28 — 0.82]-Study of Sudden Infant Death, the largest and most recent case - control study of SIDS, found that exclusive breastfeeding at 1 month of age halved the risk of SIDS (adjusted OR: 0.48 [95 % CI: 0.28 — 0.82]-study of SIDS, found that exclusive breastfeeding at 1 month of age halved the risk of SIDS (adjusted OR: 0.48 [95 % CI: 0.28 — 0.82]-RRB-.

Two later studies not included in these meta - analyses reported equivalent or even larger protective associations.265, 266 The mechanism for this apparent strong protective effect is still unclear, but lowered arousal thresholds, favorable modification of autonomic control during sleep, and maintaining airway patency during sleep have been proposed.247, 267, — , 270 It is common for the pacifier to fall from the mouth soon after the infant falls asleep; even so, the protective effect persists throughout that sleep period.247, 271 Two studies have shown that pacifier use is most protective when used for all sleep periods.169, 266 However, these studies also showed increased risk of SIDS when the pacifier was usually used but not used the last time the infant was placed for sleep; the significance of these findings is yet unclear.

In one study, a large reduction in blood pressure associated with having been breastfed for at least 3 months (Web table 1) was reported to have been somewhat attenuated after controlling for current weight, age, birth weight, time of birth, birth order, mother's age, and history of high antenatal maternal blood pressure (14), but quantitative estimates suitable for inclusion in the meta - analyses were not available.

The case - control study, published online in of the Journal of the American Academy of Dermatology, used a large clinical database of electronic medical records to collect detailed data of cutaneous melanomas developing in 462 women aged 49 years or younger.

More large - scale, randomized controlled studies are needed to tease out the risks and benefits.

Commenting on the study, ESMO spokesperson Dirk Arnold, MD, PhD, from Instituto CUF de Oncologia in Lisbon, Portugal, said «this large population - based cohort - control study impressively confirms the hypothesis of an association of colorectal polyps with diets and other life - style factors.

The researchers write that a large - scale, controlled and randomized study should be conducted to validate their findings.

The study, published in today's edition of CBE - Life Sciences Education, is the largest and most carefully controlled analysis to date of how participating in course - based undergraduate research experiences affects students» outcomes.

«The extent of fault creep, and therefore locking, controls the size and timing of large earthquakes on the Northern San Andreas Fault system,» said James Lienkaemper, a co-author of the study and research geophysicist at U.S. Geological Survey (USGS).

In Europe and China, a series of large - population studies confirmed that mutations in the area of the genome controlling MHCI increase the risk of schizophrenia.

The ability of the inorganic component of sea spray particles to take up water has been the focus of this international study where a large suite of well - controlled laboratory experiments have shown, for the first time, that the hygroscopicity of the inorganic component of sea spray is significantly lower than pure sodium chloride, a substance routinely used to describe their hygroscopicity in climate models.

The study, «Prevalence of hypertension, awareness, treatment and control in the Hispanic Community,» led by Dr. Paul D. Sorlie of the National Heart, Lung, and Blood Institute (NHLBI), sampled 16,400 individuals, making it one of the largest and most rigorous health studies of the Hispanic community.

Based on these points, Dr. Canli suggests a major research step would be to conduct large - scale studies with depressed patients, controls, and infectious - disease related protocols to determine the association or causal nature of infectious disease and depression.

We wanted to test those findings in a larger, controlled study.»

For the study, Dorevitch and colleagues estimated the number of recreational waterborne illnesses using data from two large epidemiological studies as well as reports of water - borne disease outbreaks from the Centers for Disease Control and Prevention, or CDC.

Women using depot medroxyprogesterone acetate (DMPA), commonly known as Depo - Provera or the birth control shot, have a moderately increased risk of becoming infected with HIV, a large meta - analysis of 12 studies involving more than 39 500 women published in The Lancet Infectious Diseases has found.

Researchers leading a large, ongoing study in women called VOICE that compares PrEP with pills to a vaginal microbicide plan to revaluate the ethics of continuing to use a placebo control group given the new evidence of oral Truvada's powerful impact.

The study is the largest placebo - controlled trial in older men conducted on the subject to date.

Author Sheila Crowell, assistant professor of psychology at the U, says that results of the large and tightly controlled study also suggest that as an entertainment medium, 3 - D may not provide a different experience from 2 - D, insofar as evoking emotional responses go.

«Testosterone therapy improves sexual interest, function in older men: Largest placebo - controlled study to date finds testosterone can address low libido, erectile dysfunction.»

In the largest study of its kind, using Centers for Disease Control data on nearly 14 million linked infant birth and neonatal death data, term singleton U.S. births, researchers at New York - Presbyterian / Weill Cornell Medical Center found the absolute risk of neonatal mortality was 3.2 / 10,000 births in midwife hospital births, and 12.6 / 10,000 births in midwife home births, and it further increased in first - time mothers to 21.9 / 10,000 births in midwife home deliveries.

The UI study, which was the largest of its kind in the world to date, recruited and assessed 95 pathological gamblers and 91 control subjects, matched for age, sex, and level of education, from Iowa, as well as 1,075 first - degree adult relatives of the study participants (first - degree relatives include parents, siblings, and children.)

While the current study controlled for a large number of vascular risk factors, no information was available for vascular biomarkers, and migraine specifics, such as migraine aura.

... Finally, this study draws attention to the need for large controlled clinical trials to determine if a combination of fall prevention strategies and treatment with bone - active drugs might produce additive benefits on fractures, especially in high - risk populations such as those living in nursing homes.

«If we find that we are able to reduce the recurrence rate of autism within families substantially enough, others will want to study this in larger groups with larger controls.»

A related study, also published in PLOS Genetics, shows that RPM - 1 functions as a part of a novel pathway to control β - catenin activity — this is the first evidence that RPM - 1 works in connection with extracellular signals, such as a family of protein growth factors known as Wnts, and is part of larger signaling networks that regulate development.

These include the behaviour of the Italian government in the aftermath of Chernobyl, the basis of decision - making in civil nuclear power in Switzerland and France, and the controversy over the supposed effects of radiation doses to fathers on their offspring at Sellafield (a large case control study, which has recently been published, contradicts the views in the book), and the Black enquiry into childhood leukaemias in the vicinity of the plant.

Although several large studies have shown that α - synuclein levels are lower in the CSF of PD patients and those with related synucleinopathies compared to controls, its role in cognitive decline and dementia had been unexplored.

«This study confirms several other reports in the literature,» said Dr Letur, «with a large sample and matched control group.