Results from
the largest genetic study of glaucoma, a leading cause of blindness and vision loss worldwide, showed that two genetic variations are associated with primary open angle glaucoma (POAG), a common form of the disease.
The analysis is
the largest genetic study ever of the Khoe and San peoples.
SOMEWHERE in the heart of Asia was where dogs became man's best friend — according to
the largest genetic study yet.
And
the largest genetic study of autistic children and their parents to date has located a host of new variations in autistic individuals.
The project is led by the Cross-Disorder Group of the Psychiatric Genomics Consortium and is
the largest genetic study of psychiatric illness to date.
«
Largest genetic study of mosquitoes reveals spread of insecticide resistance across Africa: New intelligence to help towards campaign against malaria in Africa.»
Dogs became man's best friends somewhere in central Asia close to Nepal and Mongolia, according to
the largest genetic study yet.
Largest genetic study of fish labeling accuracy.»
But the world's
largest genetic study of the condition «shows that autism is many different diseases,» says Stanley Nelson, a professor of genetics and psychiatry at UCLA who collaborated on the investigation.
SMART GENES
A large genetic study turns up more genes that may help build intelligence into the brain.
Many of the most obvious common diseases already had
large genetic studies under way.
Not exact matches
This is the second generation of the API undertaking and will extend the
study to a
larger share of people who have the APOE4 gene, which is a major
genetic risk factor for Alzheimer's.
«[A.I.] can help analyze
large data sets from sources such as clinical trials, health records,
genetic profiles, and preclinical
studies; within this data, it can recognize patterns and trends and develop hypotheses at a much faster rate than researchers alone,» says Deloitte.
Low levels of physical activity and inefficient sleep patterns intensify the effects of
genetic risk factors for obesity, according to results of a
large - scale
study presented at the American Society of Human Genetics (ASHG) 2017 Annual Meeting in Orlando, Fla..
In contrast, the new
study made use of wrist accelerometer data, which is more objective and quantifiable, and a
large genetic dataset from about 85,000 UK Biobank participants aged 40 to 70.
A
large - scale
genetic study published in The Lancet in 2012 found no relationship between gene variants that increased HDL and the likelihood of heart attack (though this research did not evaluate the SCARB1 variants).
The authors note that while the sample size of the meta - analyses was
large (123,132 to 260,861 participants in different
studies), they used only GWAS summary statistics and can not estimate all
genetic variance factors; some
studies also used different methodologies.
Yet, in this latest,
large - scale
study, tens of new
genetic risk factors were discovered.
The
study of the current biodiversity of plants thus enables us to go back in time and gradually sketch the
genetic portrait of the common ancestor of a
large proportion of modern - day flowers.
«
Large - scale
genetic study provides new insight into the causes of migraine.»
In conclusion, these results highlight the importance of
large - scale
genetic studies to better characterize complex diseases.
Unlike «big data»
genetic studies, which have loosely linked hundreds of
genetic changes to schizophrenia but can not explain varying symptoms, the new
study revealed distinct disease versions that may affect
large slices of patients and enable precision treatment design, say the authors.
African populations harbour the greatest
genetic diversity and have the highest per capita health burden, yet they are rarely included in
large genome
studies of disease association.
A
large - scale
genetic study of the links between telomere length and risk for five common cancers finds that long telomeres are associated with an increased risk of lung adenocarcinoma.
The
largest of its kind, the
study examined
genetic data in 100,000 individuals including 40,000 people with a diagnosis of schizophrenia and also found that some of the genes identified as increasing risk for schizophrenia have previously been associated with other neurodevelopmental disorders, including intellectual disability and autism spectrum disorders.
In addition to helping farmers check crop health, the new system will be helpful for
studying how plants respond to changes in growing conditions and for high - throughput phenotyping, an automated method used in crop research and development to analyze how
genetic modifications affect plant characteristics such as leaf size or drought resistance in a
large number of plants.
By measuring the levels of various substances in the shoots of the legume, which lives in symbiosis with fungi, and combining the results with
large - scale
genetic studies, the researchers have found that the levels of secondary substances (flavonoids and terpenoids) rise in the shoots as a result of the increased hormonal levels.
The association
study matches
genetic variants with a trait by looking at
large groups of people with that trait and then compares how their genomes differ from a group without the trait.
Large - scale
genetic study defines relationship between primary sclerosing cholangitis and other autoimmune diseases.
Of these twelve
genetic regions, six are also associated with IBD, while the six other regions showed little to no association in a recent
large study of IBD.
The
study also included
genetic data from eight extant species, including the three
largest lemur species still alive today.
Their efforts are part of a
larger push to
study more than 300 known
genetic hair disorders, which range from rare diseases detected in a few dozen families to male - pattern baldness, which affects hundreds of millions.
Segal doesn't try to explain such spookily synchronized outcomes, but her
studies suggest that the harmony between identical twins stems in
large part from shared
genetic identity.
Although previous
studies have found that a
large percentage of hair colour variation is explained by heritable factors, previous
genetic studies only identified a dozen or so hair colour genes.
Before this
study — the
largest of its kind — conducted by a team led by Professor Dirk Inzé, scientists had little insight into the genes and
genetic processes that drive some plants to limit their growth under drought conditions while others grow normally.
As the
largest ever
genetic study on pigmentation, it will improve our understanding of diseases like melanoma, an aggressive form of skin cancer.
«We have made great efforts and spent many nights in the field to cover
large parts of Poland when sampling saliva from the two tree frog species for
genetic analyses,» said Tomasz Majtyka, the University of Wroclaw and equal first author of the
study.
The
largest ever
genetic study of mosquitoes reveals the movement of insecticide resistance between different regions of Africa and finds several rapidly evolving insecticide resistance genes.
The Navajo — at almost 300,000, the
largest tribal population — have ruled out all participation in
genetic studies.
The
study found the
largest correlation between
genetic risk factors and blood pressure.
As far as we're aware, it's the first
study worldwide to show this in such detail, including a
large number of
genetic variants.»
«Jaguar scat
study suggests restricted movement in areas of conservation importance in Mesoamerica: Noninvasive
genetic survey on wild Mesoamerican jaguars is
largest of its kind, reveals conservation priority.»
And
large, genome - wide
studies searching for
genetic underpinnings for more common diseases, such as lung cancer or autism, have pointed to the nether regions of the genome between the protein - producing genes — areas that were often thought to contain «junk» DNA that was not part of the pantheon of known genes.
Neanderthal
genetic material is found in only small amounts in the genomes of modern humans because, after interbreeding, natural selection removed
large numbers of weakly deleterious Neanderthal gene variants, according to a
study by Ivan Juric and colleagues at the University of California, Davis, published November 8th, 2016 in PLOS Genetics.
«Recently,
large - scale
genetic studies have shown that certain genes contribute to adult substance use disorders.
«
Largest ever genome - wide
study strengthens
genetic link to obesity.»
A
large long - term
study at New Zealand's Dunedin School of Medicine demonstrated a
genetic basis for the different ways that people respond to emotional stress — and in the process raised new questions about how antidepressant drugs actually work.
In the
largest study of its kind,
genetic changes causing neurodevelopmental disorders have been discovered by scientists at the Wellcome Sanger Institute and their collaborators in the NHS Regional Genetics services.
In the new work, researchers looked at
genetic and health data on more than 100,000 individuals from previous
large studies to determine whether
genetic alterations that are associated with vitamin D levels predispose people to asthma, dermatitis, or high IgE levels.
The
largest ever
genetic study of children with previously undiagnosed rare developmental disorders has discovered 14 new developmental disorders.