Sentences with phrase «late in the diseases»

However, researchers have long thought that tumors don't release intact cells into the bloodstream until relatively late in the disease, and then only in vanishingly small numbers.

Therapy could come in the form of new drugs, but some experts suspect drug trials have failed so far because compounds were tested too late in the disease's progression.

Physiotherapy (PT) and occupational therapy (OT) have been traditionally used later in the disease.

But therapies that target common molecular pathways active late in disease could be part of a multi-pronged treatment plan for people with these inherited conditions.

The result is that Alzheimer's is generally detected very late in the disease process, if it is correctly identified at all — a blueprint for treatment failure, because the illness has already irreparably damaged the brain.

«Then we let the atherosclerosis develop and progress [in mice] in order to see where those cells were later in disease.»

The team found that most of the genetic changes in the original breast tumour were also present in the metastatic tumours, showing that the cancer cells spread late in disease development.

Getting Alzheimer's drugs to market requires long and costly clinical studies, which some experts say have failed thus far because experimental drugs were tested too late in the disease process.

The findings emphasize the value of implementing palliative medicine soon after a cancer diagnosis rather than waiting until later in the disease's progression.

Jeffrey Goldberg, MD, PhD: The toughest part of diagnosing glaucoma is that in most patients it affects the peripheral vision, the edges of your vision, first, and the center of your vision very late in the disease.

Unfortunately, even if we do see slowing or improvement in early HD, it's likely that there will be a point later in the disease where the drug doesn't produce significant benefits.

Now this latter element, it turns out that we have a real opportunity because as Dave Calkins and others have now demonstrated very beautifully in animal models, and we even have very good data now in humans; in glaucoma there's an injury that happens first, and it's the death or loss of the cell that happens later in the disease.

So, intraocular pressure may be elevated, axon transport fails, the axon ends up being physically damaged; the retinal ganglion cells die relatively late in the disease.

Later in the disease, weakness and muscle atrophy may occur in the hands, resulting in difficulty with fine motor skills.

Recent Alzheimer's drug trials have disappointed, perhaps because the drug was given too late in the disease.

The problem is that two thirds of cases are not diagnosed until late in the disease, when the chances of survival reduce dramatically.

Serum bilirubin is not elevated until late in the disease.

Slow but progressive weight loss is common in cats with FIV, often followed by severe wasting late in the disease process.

Even when surgery follows caval syndrome rapidly, treatment often fails, and a dogs chances this late in the disease's progression are slim.

Regenerative nodules remain undetected until late in the disease when they are usually not curable and the course of the disease is short, sometimes only weeks.

Problems caught early can often be treated more effectively than those that present much later in the disease.

SIGNS OF HEARTWORM DISEASE ARE NOT USUALLY SEEN UNTIL VERY LATE IN THE DISEASE PROCESS Coughing, breathing difficulties, vomiting and weight loss may be observed.

And late in the disease, their immune systems may be too weakened to produce antibody in quantity.

However, by the time a veterinarian can feel a tumor in the abdomen, it may be later in the disease process and carry a less than desirable prognosis.

Cataracts may occur and generally occur later in the disease.

Note: Many dogs do not develop the classical ear margin crusts until later in the disease.

When the tumor has moved, later in the disease these dogs may have a cough.

Muscle tremor, fits, and paralysis usually occur later in the disease.

The number one reason dental disease goes untreated is that in most cases, there are few signs or symptoms until very late in the disease process.

But when the cat is brought in late in the disease, the pet may need heart support before its thyroid problem can be dealt with.

Signs usually do not show up until late in the disease, when the dog suffers from internal bleeding due to the tumor rupturing.

Well for starters, there are generally little to no visible signs of the disease process, so most owners don't notice problems until late in the disease process.

Not exact matches

Tehrani targeted the most conservative companies in the business, ones that had no presence in a particular class of disease targets, to entice those who might jump on the bandwagon later.

The equipment is there for a good reason and can stop you from suffering with work related diseases later on in life.

Weeks later, Yee realized that he didn't have the equipment he needed to pluck out of Ziskin's blood the rare (perhaps one in 100,000) T cells that could identify the subtle peptide markers on the surface of her cancer cells and attack the disease.

«Right now, there is absolutely no question that there is an association between having a history of repetitive hits to the head and later - life neurodegenerative disease, and in particular chronic traumatic encephalopathy,» says Dr. Robert Stern, professor of neurology at the Boston University School of Medicine, and director of clinical research at BU's Chronic Traumatic Encephalopathy Center.

By 1890, the same disease appeared in Gros Michel crops in Costa Rica and Panama, and 20 years later, it was finally attributed to the fungus Fusarium oxysporum f.sp.

Still, more drugs are in late - stage trials that could have an impact on the disease, and researchers are pinning hopes on diagnosing the disease early, before symptoms even show up.

«We got involved in biotech in the late 90's when two of our children were diagnosed with a rare genetic disease... at the time there was nothing,» said Crowley «So we really focused as parents initially on what could we do to help drive science to a cure.

In a late - stage trial, Darzalex combined with Velcade and chemotherapy slashed patients» risk of worsening disease or death by a stunning 61 % compared with the results for Velcade and chemotherapy alone.

Various studies at the time suspected sugar was bad for the heart, and the latest JAMA suggests the Foundation paid the researchers to counter those arguments and «downplay early warning signs that sucrose consumption was a risk factor in [coronary heart disease].»

The studies conducted in the late 60s that suggested fat intake was a greater risk factor for heart disease than sugar consumption were actually funded by the Sugar Research Foundation, according to a new analysis published Monday in JAMA Internal Medicine.

The effort aims to «bring us closer to curing diseases like cancer and diabetes — and give all of us access to the personalized information we need to keep ourselves and our families healthier,» Obama said at the time of the announcement in late January.

The Centers for Disease Control is reportedly aiming its latest series of anti-smoking ads in areas where smoking rates are the highest.

The global health community and a coalition of public - private initiatives has successfully begun taming the scourge, with a 21 % decrease in its global incidence and 29 % drop in mortality rate between 2010 and 2015; still, there were 212 million malaria cases worldwide and nearly 430,000 deaths from the disease in 2015, according to the latest World Health Organization (WHO) figures.

In late 2013 his father, Riley Bechtel, who had served for 24 years as CEO, retired four years early at 61 after being diagnosed with Parkinson's disease.

The WHO assessment factored in the latest understanding of the disease and actions taken by Brazil, said Chan, adding that she would be going to the games in Rio de Janeiro.

The Centers for Disease Control and Prevention says smoking rates have fallen from 21 percent of the adult population in 2005 to 15 percent in 2015, when the agency conducted its latest survey.

The company is also seeking deeper inroads into rare diseases, with a number of assets in late - stage development, and last year it scored a major regulatory win when Europe approved its «bubble boy syndrome» gene therapy Strimvelis.

Health officials in Texas have already announced the death of a 77 - year - old Harris county resident from Vibrio: She came into contact with flood waters when they ripped into her home, and later died as a result of flesh - eating disease.