Sentences with phrase «late stage advanced»

The ultimate goal is to develop new and better approaches for genetic engineering of stem cells to be tested within a clinical trial for the treatment of late stage advanced cancers.

Not exact matches

But a late - stage clinical trial called CheckMate - 026 for the drug failed to meet its primary goal of halting cancer progression in advanced, untreated patients whose tumors consisted of at least 5 % PD - L1.

«With Ablynx, we continue to advance the strategic transformation of our research and development, expanding our late - stage pipeline and strengthening our platform for growth in rare blood disorders,» Sanofi Chief Executive Officer Olivier Brandicourt said.

Now, according to the company mission, «Golden Spike will exploit these advances, and others in the late stages of development, for commercial use, to offer human expeditions to the Moon at prices comparable to robotic flagship missions.»

This year, Flatiron Health teamed up with Guardant Health, a company that makes genetic - cancer tests for people with advanced or late - stage cancer.

That's a clear win for Gilead, according to some of the analysts who have been watching this late - stage program advance at a rapid pace.

ZURICH (Reuters)- Roche's Tecentriq immuno - oncology drug failed a late - stage follow - up trial against advanced bladder cancer, the Swiss drugmaker said on Wednesday, raising questions about whether regulators could scale back their approval of the medicine.

By: Robyn Wilkinson 4th November 2016 There is an increasing investment trend involving near - surface, easily mined base metal oxide deposits in Africa that can generate early cash flow amid current commodity prices to fund further exploration of the deposit at a later stage, advances specialist consultant to the mining industry The... →

Others advance from mid-stage to being late - stage, pre-IPO companies.

The Gospels, besides being relatively late, were written to meet the practical needs of the rapidly growing Christian community and reflect a stage of relatively advanced theological and institutional development.

The ancient Greeks saw all of nature as alive and themselves as but the most advanced stage in what Lovejoy was later to term the «great chain of being.»

21:22 - 25); but while it is harshly in conflict with the measure of mercy evident in much of the later legislation, it clearly represented in an early stage an ethical advance in placing a limit upon damages.

On the HealthTech stage, exhibitors will deliver presentations covering latest advances in hardware, software, materials and services.

Ishida's just - launched bagmaker for snacks will take centre stage at this year's Gulfood Manufacturing alongside the company's latest developments in multihead weighers, tray sealers and advanced quality inspection system.

Coconut oil does seem to be more effective in those who do not have advanced stages of Alzheimer's and are still in the earlier stages, although we have seen a few testimonials for late - stage Alzheimer's as well (See: Woman with End - stage Alzheimer's Sees Improvement in One Week after Starting Coconut Oil)

Ishida's just - launched bagmaker for snacks will take centre stage at this year's Gulfood Manufacturing alongside the company's latest developments in multihead weighers, tray sealers and advanced quality inspection systems.

Ishida's just - launched bagmaker for snacks will take centre stage at this year's Gulfood Manufacturing alongside the company's latest developments in multihead weighers, tray sealers and advanced quality inspection systems, underlining the company's versatility in meeting a huge variety of food packing requirements.

Radiologists came from across the hospital to peer at the results, disbelieving: A perfectly healthy 21 - year - old nonsmoker with no family history of the disease had lung cancer, which three days later would be diagnosed as stage IV, the most advanced form.

Ranked 4th in the world (according the latest FIFA world rankings), the sheer star power and ability of captain Cristiano Ronaldo should make them second favourites to advance to the knockout stages from Group G.

«What can we do to ensure that, if the leave campaign looks to be gaining momentum at a late stage, that will not be used to pretend that there are things on the meeting's agenda to try to change people's opinions, or that things will not be leaked in advance of that meeting to try to give people the impression that the Government have agreed a better deal than is actually the case?»

According to him, the gunboats which have reached advance stages of completion will be fitted with anti-ballistic protection and latest technology.

«Such advances in sequencing technology facilitate rational precision therapies for individuals with late - stage cancer.»

«Although there is a high risk of progression to decompensated cirrhosis and liver cancer among patients with advanced fibrosis, limiting access to people who have already progressed to late - stage disease as compared to treating earlier to prevent these liver - related complications seems counter-intuitive as a public health strategy.»

Since the late 1990s, San Francisco Bay Area has consistently had the lowest percentage of advanced - stage diagnoses for prostate cancer.

Trial participants have advanced disease with geography atrophy — considered a late stage in dry AMD — and very poor visual abilities.

Up to half of women with advanced - stage ovarian cancer might be cured, compared to the current 20 per cent survival rate, argues Dr. Steven Narod, senior scientist at Women's College Research Institute, who calls for a new standard of treatment for women with late - stage ovarian cancer.

The research also indicates that a low protein, low salt diet may not only slows the progression of CKD as an effective adjunct therapy, but it can also be used for the management of uremia, or high levels of urea and other uremic toxins in the blood, in late - stage or advanced CKD and help patients defer the need to initiate dialysis.

The high mortality rate is mainly due to late diagnosis of the disease, when it is already in an advanced stage.

Early detection offers the best opportunity for treating and surviving cancer, however, liver cancer often advances undetected and is almost always diagnosed when it has reached late stages.

While expression levels of all marker genes remained almost unchanged in wild - type ACVR1 cultures compared with the empty viral vector, the expression profile induced by caACVR1 Q207D displayed evidence of advanced chondrogenic differentiation as shown by decreased levels of the early differentiation stage marker collagen type II together with enhanced expression of the later - stage markers Ihh and collagen type X. Indian hedgehog has been shown previously to be induced by BMP signaling transmitted via the ACVR1 receptor (9).

The Learning Collaborative will engage a for - profit partner to advance auranofin through late stage drug development, registration and commercialization.

The autopsy study revealed that an additional 8 % of children in late childhood or early adolescence had progressed beyond the fatty - streak stage and had developed more advanced, focal lesions.

Results from these behavioral assays show that J147 has the ability to rescue the cognitive decline and disinhibition phenotype associated with AD when administered at an extremely late stage in the disease progression when pathology is already far advanced.

Lung cancer is the leading cause of cancer mortality worldwide, suffering from a late stage of disease at the time of diagnosis and a paucity of effective therapeutic strategies to treat advanced tumours.

For Dr. Daniel Grossman, a professor of obstetrics, gynecology and reproductive sciences at the University of California at San Francisco and director of Advancing New Standards in Reproductive Health, if lawmakers want to curb abortion at a later stage, they should make it easier for women to access care in the early stages of the pregnancy.

So it is good to share your expectations and goals in advance so that you can avoid the complications at a later stage.

Some couples never advance to the later stages of a relationship because they aren't compatible or a lack of emotional maturity.

The initial eliminations were based on the all - important «pitch,» whereas later eliminations were decided by full reads from Publisher's Weekly reviewers (participants who had advanced to that stage were provided with the PW review of their works).

The latest e-reader news has it that the color displays are in an advanced stage of development and samples have already been provided to leading e-reader manufacturers which includes Amazon and Barnes & Noble among others though there is no definite partnership reached with any e-reader manufacturer as of now.

Many chronic diseases begin slowly and are clinically silent (or invisible) until later more advanced stages.

We give priority to quality over quantity and, above all, the safety of our clients, leading us to the various stages of training (beginner, advanced and competition) as well as for different environments (social or recreational and competitive) with the aim of bringing anyone to surf through a safe and fun process of teaching and learning, based on the latest research in training methodology of Surfing.

While your little transport can take a hit or two, you will need to employ tactics to ensure that you use your power - ups at the latest possible stage or risk being blown to smithereens as the waves continue their relentless advance.

The action becomes so intense in later campaign stages that you will be forced to learn to build quickly in order to have some form of cover against the advancing horde of enemies coming your way.

In advance of Bomberman's glorious return to the console world stage later this week in Super Bomberman R for the Nintendo Switch, it's worthwhile to review the bomber king's mighty legacy across the console, handheld, and mobile gaming spaces.

Echoing the promised utopia and oft - dismal reality of advanced technological networks and intimating at the vague disillusion of late - stage capitalism, Bleeding Edge features site - specific installations and new media works by artists Anthony Antonellis, Kelsey... Continue reading Bleeding Edge An Immersive Triumph at Hudson Valley Center for Contemporary Art

Ice observations taken from the Norwegian research vessel Lance in the pack ice north of Svalbard in late July / early August report the ice edge at 81.5 N and pack ice in the advanced stages of melt.

When the consent order was made on 20 July 2006, although the husband had not received an offer of employment from his new employers, the negotiations were at a very advanced stage and in fact, a contract he later signed on 31 July was in his hands only a few hours after the consent order was made.

Medical advances are being made against the disease and some of the latest treatments offer a much greater life expectancy, but you must be in the early stages to benefit.

Even at firms where such symptoms have apparently progressed to an advanced stage, it is often not too late to begin to institute a corrective program.

You might even be in late stages with advanced Kimmelsteil - Wilson disease and they will never know!