Sentences with phrase «later stages level»

They do have the advantage of an extra 24 - hours recovery ahead of this game with United playing Bournemouth away on Wednesday night and that could be crucial, especially if the game heads into the later stages level and extra time is required.

Not exact matches

Intarcia has completed several late - stage clinical trials in which it uses the pump to deliver a glucose - controlling drug continuously for months — an idea, that if successful (and approved by the FDA) could significantly help patients with type 2 diabetes, fewer than half of whom maintain the recommended glycemic levels.

Ahern breaks down the challenge of scaling into three stages based on funding levels — Early (during which a company raises, seed, Series A and B funding), Growth (Series C and D), and Later (Series E to IPO).

In that case, high GDP growth levels simply disguise the seeming collapse of underlying economic growth in a way that has happened many times before — always in the late stages of similar apparent investment - driven growth miracles.

The lead bank plans to keep rates at their current level for the foreseeable future, perhaps even until the late stages of 2014.

We test (and encourage others to test) all of our crops (indoor and outdoor) throughout the later stages of flowering to ensure THC levels are not elevating unexpectedly.

Only in the later stages of the cognitive process does a form become disengaged from association with the individual and thus reach the level of an abstract universal.

I feel he would be available for a cheap price as he has not played much football recently but getting his fitness level up at such a late stage of pre-season and meeting his wage demands could be problematic.

Once you are pregnant, the level of hormones increases in your body speedily which at later stages also prepares the shape of a woman for the delivery.

Much of the attention in the later stages of the campaign has centred on the Labour party, which is split on the issue at every level.

A statement issued by the Coast Guard late Wednesday said Poulin «has suspended future rulemaking decisions and directed a formal risk identification and evaluation of the Hudson River, known as a Ports and Waterways Safety Assessment (PAWSA)... a disciplined approach to identify major waterway safety hazards, estimate risk levels, evaluate potential mitigation measures and set the stage for implementation of selected measures to reduce risk.»

Whether you are at the very early stage of finding seed capital — finance required for developing «proof of principle» — or at the later level of «start - up,» there are some key funding resources to explore, both regionally and nationally.

The team found that blood levels of THBS2, combined with levels of a known later - stage biomarker called CA19 - 9, was reliable at detecting the presence of pancreatic cancer in patients.

In type 1 and late - stage type 2 diabetes, the pancreas loses insulin - producing beta cells, increasing instability in blood sugar levels.

For example, a rexinoid approved for treating certain types of late - stage cancer raises levels of lipids called triglycerides in the blood, which could worsen obesity and cardiovascular disease.

«These medications are often stopped when patients are in the late, but pre-dialysis, stages of kidney disease because of the risk of dangerously high potassium levels.

LIWC categories associated with informality (leisure, assent) and impulse (anger, swear words, sexual, body, ingestion) were generally associated with declining ego level, while the relationship of ego development to verbosity or response length showed the greatest increases at the later stages of development.

But while this approach is good at diagnosing the disease at later stages, it can miss the disease early on when antibody levels are low.

Its levels declined again in late - stage patients with full dementia, closely mirroring the pattern of microglia activity during the course of the disease.

«By using both of these compounds — a blocker at the early stage of injury, and an activator at the later stage — we're able to complement the brain's natural healing processes and maintain a reduced level of swelling,» he says.

The drug, bexarotene, was found to reduce levels of the neurotoxic protein amyloid - beta in experimental mice with late - stage Alzheimer's but to increase levels during early stages of disease.

The research also indicates that a low protein, low salt diet may not only slows the progression of CKD as an effective adjunct therapy, but it can also be used for the management of uremia, or high levels of urea and other uremic toxins in the blood, in late - stage or advanced CKD and help patients defer the need to initiate dialysis.

In addition, blood estrogen levels at late stages of pregnancy were found to be about two times higher in Nrk mutant mice than in wild - type mice, suggesting that Nrk is also involved in the regulation of synthesis or secretion of estrogen.

However, virus strains that can utilize CXCR4 either in place of (X4 HIV) or in addition to CCR5 (R5X4 HIV) are found at significant levels in roughly 50 % of late - stage infected individuals [7], [8], supporting the need for therapies targeted to CXCR4 [9].

While expression levels of all marker genes remained almost unchanged in wild - type ACVR1 cultures compared with the empty viral vector, the expression profile induced by caACVR1 Q207D displayed evidence of advanced chondrogenic differentiation as shown by decreased levels of the early differentiation stage marker collagen type II together with enhanced expression of the later - stage markers Ihh and collagen type X. Indian hedgehog has been shown previously to be induced by BMP signaling transmitted via the ACVR1 receptor (9).

Furthermore, later - stage DSTs (such as those focusing on regulation) or higher level strategic tools (such as those focusing on portfolio management) might be readily applied to both autologous and allogeneic cell therapies.

A low - fat muffin and large latte raises your insulin levels and jacks up your stress hormone cortisol, setting the stage for a late - morning crash that will leave you running for another sugary, caffeinated pick - me - up.

The risk of migraine was highest during the later stage of perimenopause, when women have low levels of estrogen, the study found.

«Risk was highest at the later stage, when women have low levels of estrogen,» says lead study author Vincent Martin, MD, director of the Headache and Facial Pain Center at the University of Cincinnati Gardner Neuroscience Institute.

Conversely, within non-diabetic populations, periods of IER (75 - 85 % ER on restricted days) do not typically affect fasting glucose levels 37, 41, 45, 48 or HbA1c 41, 48; results of which can often be replicated by short term CER studies.62 - 65These findings are unsurprising given that frank hyperglycaemia within the T2DM diagnostic range is effectively a late - stage manifestation of IR, which along with compensatory increases insulin secretion, can precede the onset of T2DM by many years.66, 67 Findings from one large scale prospective cohort study, Whitehall II, reveal a sharp increase in the trajectory towards fasting hyperglycaemia which is only detectable three years prior to diagnosis with T2DM.67 Consequently, it can be argued that changes in circulating insulin concentrations, fasting (hepatic) insulin sensitivity and glucose uptake / clearance are more sensitive markers of deteriorating glucose control than fasting glycaemia in non - diabetics.68 - 70

In late stage adrenal fatigue, your body is no longer able to effectively regulate cortisol levels correctly.

Blood glucose levels are maintained even through the late stages of starvation, and cancer cells can evolve insulin - independence and the ability to import glucose massively from blood.

I actually don't know what that is, but it's clearly significantly harder than 55 % of VO2max, because two thirds of the subjects (who were trained, recreationally competitive cyclists) were unable to complete the trial at that level and had to lower the power to 50 % Wmax during the later stages of the trial.

Let me put it this way: your MAX HR measures the maximum stress your body can handle at any given time, and your stress levels correspond directly your heart rate, unless you are in late - stage overtraining.

(However, decreased performance levels may not be evident until middle and later stages of overtraining.)

I breezed through many stages right after being stuck on the previous one and the later levels are much too difficult.

Don't worry though, it ramps up in the later stages and really brings some demanding levels once you beat the game.

There are plenty of benefits for students in creating personalized learning paths: making career choices becomes faster, choosing the right education path becomes easier and university courses completed in high school level can be transferred as course credits at a later stage.

Our Families of Schools database has revealed, for example, that in the top performing school of one «family» of similar schools, 90 % of their disadvantaged pupils achieved a Level 4B — the level most likely to lead to getting five good GCSEs later on - or higher in their Key Stage 2 Maths Level 4B — the level most likely to lead to getting five good GCSEs later on - or higher in their Key Stage 2 Maths level most likely to lead to getting five good GCSEs later on - or higher in their Key Stage 2 Maths exam.

The latest data on those Key Stage 1 assessments - published last Thursday - showed that nearly 85 % of pupils were reading at the expected level (Level 2), with girls doing better than level (Level 2), with girls doing better than Level 2), with girls doing better than boys.

Chronic absenteeism sets the stage for poor attendance and inability to successfully do grade - level work in later grades (Attendance Works, 2013).

Even as political leaders in both red and blue states continue to back away from the standards — New York Gov. Andrew Cuomo is the latest example — the hottest battles have shifted to the local level, where education officials are staging public revolts against state and federal mandates to administer Common Core exams.

For instance, consider adding levels, transitions (such as stone), and features (such as water) at a later stage.

Yes, other mutual funds do late - stage private investing (as do some hedge funds), but few do so as often, as consistently or with the same level of success and influence.

On very rare occasions, cats in the later stages of FIV infection may test negative on FIV antibody tests because their immune systems are so compromised that they no longer produce detectable levels of antibody.

On very rare occasions, cats in the later stages of FIV infection may test negative because their immune systems are so compromised that they no longer produce detectable levels of antibody.

Contributing author «An Integrative Approach to Late Stage Chronic Renal Disease Utilizing Photobiomodulation» Low Level Laser Therapy — the History, Mechanisms and Clinic Applications Creighton University School of Medicine (scheduled release 2017)

Phosphorus levels may be suitable for early stage kidney disease but not as ideal for late stage renal failure

Distemper titers (another word for antibody level) of either the IgM type (produced in early stages of infection) and the IgG type (produced in later phases of infection) can be checked.

DISTEMPER ANTIBODY LEVELS — Distemper titers (another word of «antibody level») of either the «IgM» type (produced in early stages of infection) and the «IgG» type (produced in later phases of infection) can be checked.