Sentences with phrase «lead candidate cyad»

For example, Novartis and the University of Pennsylvania's lead candidate (CTL019) for treating a range of hematological malignancies received breakthrough status from the US Food and Drug Administration (FDA) in 2014, permitting access to an expedited drug development pathway for high unmet medical needs.

The company's lead candidate, GLN - 1001, is a first - in - class, orally available oncolytic small molecule, currently being developed as a potentially disease modifying therapy for glioblastoma by targeting specific vulnerabilities in tumor cells.

Our lead candidate, LYS - GM101, has been designed to replace this defective gene in the cells of GM1 patients, in order to allow for production of the functional lysosomal acid beta - galactosidase (bgal) enzyme.

They expect to move their lead candidate UBX0101 into human clinical trials for osteoarthritis sometime in 2018, and move on to other clinical indications after that.

In addition to AFFiRiS and Prothena, BioArctic Neuroscience AB continues to report earlier - stage but promising preclinical results with their lead candidate PD0805, a mAB targeting AS protofibrils.

For example, Novartis and the University of Pennsylvania's lead candidate (CTL019) for treating a range of hematological malignancies received breakthrough status from the US Food and Drug Administration (FDA) in 2014, permitting access to an expedited drug development pathway for high unmet medical needs (1).

By 2006, he was a lead candidate for his current U.N. post, following the death of his countryman, Joke Waller - Hunter.

During his recent fundraiser County Legislator Ed Day, the GOP's current lead candidate for the 2013 county executive race, offered some precepts and plans that people could expect as part of his administration.

As the lead candidate on the Labour regional list, even if she does lose, Kezia will be a second place winner thanks to the Additional Member System.

In Germany, the country where Juncker's name was most prominent, polls showed less than a fifth of voters even knew he was the lead candidate for the EPP.

He gained 2.01 % of the vote as the lead candidate for the Eastern region in the 2009 European elections.

It was clear Button was the lead candidate to be super-sub and he was apparently thrilled to be asked, according to Boullier:

The company doesn't have a product to sell yet, but its lead candidate, imetelstat, has produced compelling trial results that suggest it could eventually dominate a somewhat underserved niche.

This company's lead candidate, trilaciclib, is intended to prevent the blood cell devastation often caused by standard chemotherapies, and it appears to do the trick.

Given the clinical trial results underpinning a new drug application for Kite Pharma's lead candidate, which the Food and Drug Administration is currently reviewing, I'd say there's a solid chance Gilead can squeeze out a return on its investment.

During its first trial, AnaptysBio's lead candidate helped all 12 eczema patients treated to achieve a 50 % clear skin goal 57 days after receiving a single injection.

The company's lead candidate is Trevyent, a development stage drug product that utilizes SteadyMed's PatchPump technology to administer treprostinil, a vasodilatory prostacyclin analogue to treat pulmonary arterial hypertension.

Funds will help company reach clinical validation for lead candidate in X-ALD, a rare neurodegenerative and life - threatening disease

Funds will help company reach clinical validation for lead candidate in X-ALD, a rare neurodegenerative and life - threatening disease Mataró, Barcelona, Spain, October 14, 2015 — Minoryx -LSB-...]

Juno's setbacks contrast with the biologics license application planned this year by Novartis, and the rolling BLA in progress by Kite Pharma — which on Tuesday reported positive 6 - month trial data for its CAR T - cell lead candidate.

Befitting a campaign in which the leading candidate is known for a TV show that blurred the lines between reality and scripted TV drama, there are any number of sub-texts and counter-narratives in Trump's attack on Kelly.

Tedros Adhanom Ghebreyesus, a leading candidate to be the next World Health Organization director - general, is facing a stunning allegation: covering up three cholera outbreaks in his home country of Ethiopia while he was its health minister.

He is widely considered to be a leading candidate to chair the U.S. Federal Reserve should Trump choose not to retain Janet Yellen.

«They're the leading candidate in this effort and can afford to pay the most because of cost synergies and scale.»

The receivers of Great Southern will wind up the failed agribusiness» 2007 plantation scheme after leading candidates withdrew their offers.

Cristina Fernandez de Kirchner, who was president from 2007 to 2015 (Macri defeated a candidate from her coalition), has emerged as a leading candidate with a new party, Unidad Ciudadana.

In Europe, opinion polls show that the race to elect the next French president is too close to call with both leading candidates losing momentum ahead of Sunday's first - round vote.

Currently the leading candidate, with 45 nominations, is «Donald J. Trump Elementary.»

This technique, I've learned from Davis, leads candidates to eventually drop their guard and reveal how events in their lives fit together.

Four recent polls in Iowa show him within the margin of error for first place or, in one case, the actual leading candidate.

San Francisco Fed President Williams is leading candidate to become next President of the New York Fed, sources said.

But not only is he the leading candidate for the Republican nomination, and therefore someone the media has to cover, he is such a ratings win that most news outlets can't help but run as many stories about him as possible.

With promises of more transparent government, better - trained police and improved public schools, four of the leading candidates for Baltimore County executive made their pitch to voters at a forum Saturday in Woodlawn.

The leading candidate to replace him is Representative Kevin McCarthy of California, the majority leader, who is viewed more favorably by the House's more conservative members both for his willingness to bend to their will and for his cheerful manner.

7) Among the leading candidates to replace Cohn are reportedly Peter Navarro, the hardline protectionist who leads the White House National Trade Council, and Larry Kudlow, the hardline supply - sider who hosted a show on CNBC.

One of the most fortunate events in my life was to study under four brilliant economists at Stanford, who also formed my dissertation committee - Ronald McKinnon, an influential and original scholar in international economics; Thomas Sargent, a leading «rational expectations» theorist; John Taylor, also a «rational expectations» macroeconomist (currently serving in the Bush administration, and a leading candidate to succeed Alan Greenspan at the Fed, according to the Wall Street Journal), and Robert Hall, who heads the official Recession Dating Committee of the National Bureau of Economic Research.

As Summers's name has circulated as a leading candidate in recent weeks, the White House has discouraged speculation about whom Obama is going to pick, saying he is considering a range of candidates and will not decide until the fall.

One of the leading candidates to replace Bernanke is Janet Yellen, vice chair of the Fed and a stalwart defender of its existing policies.

He turned to Tiff Macklem, the bank's senior deputy governor (who is, incidentally, getting more attention these days as a leading candidate to succeed Carney when he departs next June to take over the Bank of England) to flesh out the household debt picture with details.

Correction: An earlier version of this story named David Sokol as a leading candidate to succeed Warren Buffett as CEO of Berkshire Hathaway.

Uber's board met this weekend to review its three leading candidates for the job, which has been vacant since Uber co-founder Travis Kalanick was pressured to resign in June.

Former Rep. Jeff Miller, R - Fla., who chaired the House Committee on Veterans» Affairs before retiring from Congress last year, is considered a leading candidate to become President Donald Trump's next nominee for Veterans Affairs secretary, according to several people familiar with the matter.

Triumph's lack of loan fees makes it a leading candidate for anyone looking to refinance an existing home loan.

WASHINGTON (AP)-- President Donald Trump's new attorney, Emmet Flood, a veteran of the Clinton impeachment battles, is the leading candidate to replace the White House's top lawyer, several people...

Over the next several weeks, at least six top male executives left or said they were planning to leave the company, including Trevor Edwards, president of the Nike brand, who was widely viewed as a leading candidate to succeed Mr. Parker, and Jayme Martin, Mr. Edwards's lieutenant, who oversaw much of Nike's global business.

WASHINGTON (AP)-- President Donald Trump's new attorney, Emmet Flood, a veteran of the Clinton impeachment battles, is the leading candidate to replace the White House's top lawyer, several people familiar with the matter said Thursday.

The company is rumored to be adding a new batch of cryptocurrencies this year, with Ripple XRP among the leading candidates for inclusion.

Americans will choose their next President in November 2016, and a leading candidate threatens the U.S.» established trade agreements with other countries.

Now it appears that the prickly America First advocate who played a crucial role in driving Cohn to quit could, in fact, be taking his old position: Trump administration officials are reportedly considering White House trade adviser Peter Navarro as one of the leading candidates to head the National Economic Council (NEC).

Khosrowshahi became one of three leading candidates over a weekend of board meetings, according to The New York Times, citing sources.