«We found that the immune system in a large group of patients reacted to a protein formed only in the prostate, namely the enzyme transglutaminase 4,» says
lead investigator Dr Nils Landegren at SciLifeLab, Department of Medical Sciences at Uppsala University and Karolinska Institutet's Department of Medicine in Solna.
«Our findings show that a specific genetic marker (known as allele * 2 of the HS1, 2 A enhancer region) influences not just disease activity in RA patients, but also response to therapy in the early stages of their disease,» said
lead investigator Dr Gabriele Di Sante of the Institute of Rheumatology and Related Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Not exact matches
Dr Ian Kelleher,
Lead Investigator, Department of Psychiatry, RCSI said «Our analysis shows, we believe for the first time, that cessation of traumatic experiences predicted a significantly reduced incidence of psychotic experiences compared to individuals for whom the traumatic experiences continued.
The research, which underlines the importance of maintaining a healthy body weight both before and after pregnancy, is
led by
Dr Cuilin Zhang, senior
investigator, and
Dr Wei Bao, post-doctoral fellow, Eunice Kennedy Shriver National Institute of Child Health and Human Development at the US National Institutes of Health, Rockville, MD, USA, and colleagues.
Dr Florent Ginhoux, senior principal
investigator at SIgN and
lead scientist of the study, said previous research had examined thousands of cells at once.
The
investigators,
led by
Dr Jo Appleby of the University of Leicester School of Archaeology and Ancient History, surmise that the postcranial injuries, including the potentially fatal one to the pelvis, might have been inflicted after Richard's death, on the basis that had he been alive he would have been wearing a specific type of armour worn in the late 15th century that would have prevented such wounds.
Lead investigator,
Dr Jacqueline Hamilton, from York's Wolfson Atmospheric Chemistry Laboratories, said: «The risks of tobacco exposure do not end when a cigarette is extinguished.
According to
Dr Won Park, Inha University Hospital, Korea, and
lead investigator of the PLANETAS study, «the challenge for biosimilars is to demonstrate similarity in therapeutic effectiveness, safety and immunogenicity to their reference product, not just biochemical and pharmacokinetic equivalence.»
IMB Senior Principal
Investigator Dr Bruno Reversade, one of the study's authors, who also
led the discovery of Elabela two years ago, stated, «I am very pleased that we have further uncovered a critical role of Elabela in the establishment of the circulatory system, following its discovery as a hormone essential for heart development in 2013.
«These findings demonstrate a single origin of gills that likely corresponds with a key stage in vertebrate evolution: when some of our earliest relatives transitioned from filtering particles out of water pumped through static bodies to actively swimming through the oceans,» says
lead author
Dr Andrew Gillis, a Royal Society University Research Fellow in Cambridge's Department of Zoology, and a Whitman
Investigator at the Marine Biological Laboratory in Woods Hole, US.
Dr Vivian Vignoles, Reader in Social Psychology at the University of Sussex, Principal
Investigator of the Culture and Identity Research Network, and
lead author on the project, explains:
Dr Andy Grierson, fellow
lead investigator, added: «Diseases such as ALS and FTD are commonly associated with large protein clumps that accumulate in affected nerve cells.
Dr Simon Parker, Director of York's School of Social and Political Sciences and
lead investigator for the Precarious Trajectories research project on the Mediterranean migration crisis, is one of four experts to add their voice to UNICEF Innocenti's Research Watch.
Dr Kyle Jiang,
lead investigator from the Department of Mechanical Engineering, said: «We are looking at an industrial revolution happening in peoples» pockets.
Dr Wisner is the
lead investigator of largest study of MMH disorders in the US and founder of the North American Perinatal Maternal Mental Health Society, bringing together researchers and thought leaders in MMH.