Sentences with phrase «lead to blindness in»

Worst case scenario, the untreated parasite infection could lead to blindness in humans.

Advanced Cell Technology (ACT), based in Marlborough, Mass., will begin testing its retinal cell treatment this year in a dozen patients with Stargardt's macular dystrophy, an inherited degenerative eye disease that leads to blindness in children.

Not exact matches

The price is for Spark Therapeutics» Luxturna, approved by the Food and Drug Administration in December to treat a rare, inherited retinal disease that can lead to blindness.

«The institute is seeking to grow the rice in developing countries to address severe vitamin A deficiency that can lead to blindness and other health issues,» Booth said.

Vitamin A deficiency is the leading cause of childhood blindness, and also compromises the immune system, severely reducing the body's ability to ward off infections, especially in children.

The International Rice Research Institute (IRRI) and national rice research institutes in Bangladesh and the Philippines have joined with Helen Keller International (HKI), a leading global health organization that reduces blindness and prevents malnutrition worldwide, in a new effort to further develop and evaluate Golden Rice as a potential tool to reduce vitamin A deficiency.

Over time this process becomes irreversible, leading to partial blindness in the weaker eye.

A treatment that appears safe and effective in treating natural color - blindness in monkeys might just lead to colorizing the world for similarly afflicted people, along with restoring sight to those with other retinal diseases

In the meantime, Lin said, the study provides valuable new information on ATF6's role in human development and how its malfunctioning can lead to blindnesIn the meantime, Lin said, the study provides valuable new information on ATF6's role in human development and how its malfunctioning can lead to blindnesin human development and how its malfunctioning can lead to blindness.

According to a smaller study, running also reduces the risk of macular degeneration — the leading cause of blindness in developed countries.

According to the World Health Organization (WHO), diabetic retinopathy is the leading cause of blindness in adults of working age, and its incidence is showing an upward trend.

Though this research focused on the form of the disease called Leber congenital amaurosis 2, or LCA2, the scientists and engineers involved in the study believe the technology holds promise for other forms of LCA as well as other inherited diseases that lead to severe vision loss or blindness.

Their blindness was caused by either mutations in the genes RPE65 or LRAT, leading to a serious defect in the retinoid cycle.

«This could lead to major advances in preventing the progress of some of the leading causes of blindness,» he says.

ROP involves an abnormal growth of blood vessels in the retina that may lead to scarring, retinal detachment and, in severe cases, blindness.

An imbalance in the process can lead to blindness.

The prevalence of Type 1 and Type 2 diabetes in the United States is 9.3 percent and expected to increase, along with complications associated with diabetes that include diabetic retinopathy, the leading cause of new cases of blindness among adults ages 20 to 74 in the United States.

A new technique reported in the February 2015 issue of The FASEB Journal suggests that during early stages, it might be possible to reverse age - related macular degeneration, a leading cause of blindness that is currently irreversible.

A case in point: the new gene therapy for Leber congenital amaurosis, the eye disorder that causes progressive loss of vision, usually leading to complete blindness by age 40.

In Europe and the United States, gene therapists have restored vision in individuals suffering from a rare genetic disorder that inevitably leads to blindnesIn Europe and the United States, gene therapists have restored vision in individuals suffering from a rare genetic disorder that inevitably leads to blindnesin individuals suffering from a rare genetic disorder that inevitably leads to blindness.

Mutations in the mitochondrial DNA can lead to blindness, seizures, dementia or mental impairment, and early death.

In humans, leprosy causes nerve and muscle damage which can lead to deformity, disability and blindness if left untreated.

The researchers found that mutations to a gene called ATF6, a key regulator of the unfolded protein response, can lead to achromatopsia, a hereditary visual disorder characterized by color blindness, decreased vision, light sensitivity, and uncontrolled eye movement in children.

Mitochondrial diseases affect the batteries of the cell and can lead to muscular weakness, blindness, fatal heart failure, learning disability, liver failure, diabetes and can lead to death in early infancy.

A fault in the CHM gene causes choroideremia, in which cells in the retina stop working and slowly die, leading to blindness.

«This is important because the death of photoreceptor cells is known to cause retinal degenerative diseases in humans that lead to blindness.

A leading cause of blindness in the world especially for the elderly, glaucoma is caused by high intra-ocular pressure in the eye which then leads to damage to the optic nerve.

In healthy individuals HCMV establishes lifelong latency, but in immunocompromised patients, viral reactivation can lead to severe clinical symptoms, such as disseminated viral infection, blindness and potentially canceIn healthy individuals HCMV establishes lifelong latency, but in immunocompromised patients, viral reactivation can lead to severe clinical symptoms, such as disseminated viral infection, blindness and potentially cancein immunocompromised patients, viral reactivation can lead to severe clinical symptoms, such as disseminated viral infection, blindness and potentially cancer.

Scientists in Italy have discovered a simple eye drop that may reverse glaucoma, the disease caused when pressure builds in the eye, injuring nerve cells and ultimately leading to blindness.

Two of these drugs use RNAi to shut down genes involved in macular degeneration, the leading cause of blindness in the elderly, and a third disables a deadly pneumonia - causing virus.

Researchers from Massachusetts Eye and Ear have, for the first time, identified rapidly proliferating cells (known as «neural crest - derived progenitor cells») in the corneal endothelium of specimens from normal corneas and from corneas with Fuchs» Endothelial Corneal Dystrophy (FECD), a condition in which the cells responsible for keeping the cornea clear die prematurely — often leading to blindness.

Many diseases that lead to blindness, such as glaucoma and macular degeneration, are caused by the death of certain cells in the human retina that lack the ability to regenerate.

The worm's larvae can trigger damage in the eyes, leading to river blindness if untreated.

This results in the buildup of fluid and other deposits in the eye, which can lead to blindness if not treated.

Researchers report that kittens with the disorder, a visual impairment medically known as amblyopia that leads to poor sight or blindness in one eye, can completely recover their vision by simply spending 10 days in total darkness.

Every year around 100 million people contract Chlamydia infections, which are one of the main causes of female infertility and ectopic pregnancies and can also lead to blindness — especially in developing countries.

The condition is hereditary or age - related, and causes degeneration of the photoreceptors — light - sensitive cells in the retina — leading to blindness.

There may be a connection between taking vasodilators and developing early - stage age - related macular degeneration (AMD), the leading cause of vision loss and blindness among Americans who are age 65 and older, according to a study published online in Ophthalmology, the journal of the American Academy of Ophthalmology.

Loss of, or diminished, retinal DHA leads to visual impairment and may play an important role in the development of blindness from retinitis pigmentosa and other retinal degenerative diseases, as well as age - related macular degeneration (AMD), the foremost cause of blindness in people older than 50 years.

«Fish eyes to help understand human inherited blindness: Discovery of a gene in zebrafish that triggers congenital blindness could lead to a suitable cure for similar disease in humans..»

Exchange of material between this gene and a neighboring gene associated with green light leads to a high amount of genetic variation but can result in color blindness if the process goes awry.

Glaucoma comprises a group of eye diseases that cause pressure to build up in the eye, which damages the optic nerve and ultimately leads to blindness.

Even worse, a miscalculation or lapse in regimen can cause blood sugar levels to rise too high (hyperglycemia), potentially leading to heart disease, blindness and other long - term complications, or to plummet too low (hypoglycemia), which in the worst cases can result in coma or even death.

Age - related macular degeneration, a disease that slowly degrades light - sensitive cells in the retina, is the leading cause of vision loss and blindness among people 65 and older, according to the Centers for Disease Control...

It strikes men in their twenties, leading to total blindness within three to six months of the first symptoms appearing.

Mitochondria produce energy for the cell and if they are damaged or not working correctly, it can result in the damage and eventual death of RGCs leading to blindness.

Defects in mitochondrial DNA lead to devastating genetic diseases, with such symptoms as brain abnormalities, severe fatigue, blindness or defective heart function — and can be fatal.

New York, NY, December 19, 2008 — Research to Prevent Blindness (RPB), the leading voluntary health organization supporting eye research, awarded 100 grants totaling $ 10.24 million in 2008.

In 2014, a Japanese woman in her 70s with age - related macular degeneration — a common eye condition that can lead to blindness — had a tiny sheet of retinal pigment tissue made from her own skin cells implanted into one eye, which reportedly stopped the disease's progressioIn 2014, a Japanese woman in her 70s with age - related macular degeneration — a common eye condition that can lead to blindness — had a tiny sheet of retinal pigment tissue made from her own skin cells implanted into one eye, which reportedly stopped the disease's progressioin her 70s with age - related macular degeneration — a common eye condition that can lead to blindness — had a tiny sheet of retinal pigment tissue made from her own skin cells implanted into one eye, which reportedly stopped the disease's progression.

Congratulations to William C. Campbell, Ph.D., who has been jointly awarded this year's Nobel Prize in Physiology or Medicine for the discovery of avermectin, which led to a treatment for river blindness.