Sentences with phrase «leading type of cancer»

The leading type of cancer among men is lung cancer and among women is breast cancer.

Not exact matches

Celgene's lead product, Revlimid, a drug designed to treat multiple myeloma and a few other cancer types, has been benefiting from longer duration of use, strong pricing power, and high multiple myeloma market share.

The mayor's office released no information on symptoms Maggie Daley may have exhibited that led to the testing, the type of cancer detected, its extent, or the type of treatment she will receive.

Experts are more concerned when a food contains higher levels of inorganic arsenic — a potent carcinogen that can lead to health problems later in life, including certain types of cancer.

Led by researchers at the University of Pittsburgh School of Medicine, an international panel of pathologists and clinicians has reclassified a type of thyroid cancer to reflect that it is noninvasive and has a low risk of recurrence.

It also sought to match epigenetic changes and genetic differences to the physical characteristics of each cell type and use this knowledge to understand how these can lead to blood disorders, cancer and other complex diseases.

There are concerns the vaccine, which guards against four types of the HPV shown to cause cervical cancer and anogenital warts, may give girls a false sense of security about contracting sexually transmitted infections (STIs) and lead them to engage in riskier sexual activity.

Due to an inability to differentiate aggressive cancers from nonaggressive types, physicians treat the majority of cases, which may lead to side effects such as impotence and / or incontinence.

The only VLP - based vaccine to hit the U.S. market is Merck & Co.'s Gardasil, which won FDA approval in June as preventative against certain types of human papillomavirus (HPV), which could lead to cervical cancer.

A COMPOUND that slows the proliferation of triple - negative breast cancer cells in lab tests could lead to the first drugs to target this aggressive type of tumour.

They demonstrate that high vs. low levels of physical activity engagement are associated with reduced risk of 13 cancer types (including 3 of the top 4 leading cancers among men and women worldwide).

A team led by professor Massimiliano Mazzone has demonstrated that the metabolism of macrophages, a particular type of white blood cell, can be attuned to prevent the spread of cancer.

Primary liver cancer, or hepatocellular carcinoma, is the sixth most prevalent type of cancer and third - leading cause of cancer - related deaths worldwide, according to the National Cancer Institute cancer, or hepatocellular carcinoma, is the sixth most prevalent type of cancer and third - leading cause of cancer - related deaths worldwide, according to the National Cancer Institute cancer and third - leading cause of cancer - related deaths worldwide, according to the National Cancer Institute cancer - related deaths worldwide, according to the National Cancer Institute Cancer Institute (NCI).

«However, unlike smoking, which substantially increases the likelihood of premature death (for example, mortality from lung cancer), obesity and associated Type 2 diabetes primarily lead to long - term disability, so that from a lifetime perspective, obesity could tax the health care system even more than smoking.»

That trend is problematic considering that African - Americans — the most at - risk population for multiple myeloma — have different genetics that can affect how this type of cancer progresses and what kind of targeted therapies are most effective, said Zarko Manojlovic, lead author of the study.

New research led by Li Ding, Ph.D., of Washington University School of Medicine in St. Louis, shows that current approaches to genome analysis systematically miss detecting a certain type of complex mutation in cancer patients» tumors.

Specifically, they found that chemotherapy alone leads to two types of dormant cancer cells that are not killed outright and become resistant to additional chemotherapy, but when combined with immunotherapy, a majority of dormant cells also is destroyed.

Cancer stem cells are strongly associated with the growth and recurrence of all cancers and are especially difficult to eradicate with normal treatment, which also leads to tumours developing resistance to other types of therapy.

In a new study published in Scientific Reports, Tokyo Medical and Dental University (TMDU)- led researchers investigated photodynamic detection of cancer stem cells in a glioma cell line, a model of a highly aggressive type of brain cancer.

It is known that cells without this type of DNA repair can develop mutations leading to cancer development.

His research on attaching selenium to the leading clinical chemotherapeutic monoclonal antibody for a type of breast cancer shows it can more effectively kill the cancer cells, he reports.

Another research goal is to find out whether the mutation leads to specific types of tumours or cancers that are triggered at a particular time of life.

The findings, which were published online in the journal Cancer Cell, could ultimately lead to new targeted therapies for many other types of cancer carrying similar p53 mutaCancer Cell, could ultimately lead to new targeted therapies for many other types of cancer carrying similar p53 mutacancer carrying similar p53 mutations.

«This is the very first time researchers have looked at the proportions of mutations within different cancer types and assigned them to these three factors,» said lead author Cristian Tomasetti, assistant professor of biostatistics at the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins Bloomberg School of Public Health, referring to heredity, environmental and random facancer types and assigned them to these three factors,» said lead author Cristian Tomasetti, assistant professor of biostatistics at the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins Bloomberg School of Public Health, referring to heredity, environmental and random faCancer Center and the Johns Hopkins Bloomberg School of Public Health, referring to heredity, environmental and random factors.

The work, appearing online Nov. 17 in the journal Nature, provides a possible explanation for how one type of DNA damage may lead to cancer, diabetes, hypertension, cardiovascular and lung disease, and Alzheimer's disease.

There are 14 million new infections each year, which can lead to six different types of cancers.

However, lingering infections with a subset of about 19 «high - risk» HPV types can lead to the development of cervical cancer or other genital / anal cancers.

But in both cases, tumors can become resistant to treatments — leading to the most challenging and aggressive types of those cancers.

According to the American Cancer Society, prostate cancer is the second most common type of cancer in American men (behind skin cancer), and the second - leading cause of cancer death in men (after lung caCancer Society, prostate cancer is the second most common type of cancer in American men (behind skin cancer), and the second - leading cause of cancer death in men (after lung cacancer is the second most common type of cancer in American men (behind skin cancer), and the second - leading cause of cancer death in men (after lung cacancer in American men (behind skin cancer), and the second - leading cause of cancer death in men (after lung cacancer), and the second - leading cause of cancer death in men (after lung cacancer death in men (after lung cancercancer).

The discovery, which is described online in the journal Cell, may lead to new ways to trigger cell death in some types of cancer cells.

While it is difficult to say at this point what types of cancer might be amenable to such an approach, this new concept could lead to an improvement in human cancer treatment in the long term, the researchers say.

Dario C. Altieri, M.D., Wistar's President and CEO and lead author of the study, and colleagues showed how the activation of this pathway leads to an unfavorable prognosis for patients with gliomas — a type of brain tumor — and how the pathway could be a valuable therapeutic target in cancer.

Researchers leading the largest genomic tumor profiling effort of its kind say such studies are technically feasible in a broad population of adult and pediatric patients with many different types of cancer, and that some patients can benefit by receiving precision drugs targeted to their tumors» mutations or being enrolled in clinical trials.

«The next step of our work will see how this approach works in other cancer types, and we hope it could ultimately lead to testing this technique in trials to see if it can help patients.»

In a study published in Molecular Cell this month, Alexei V. Tulin, PhD, Associate Professor at Fox Chase Cancer Center, and colleagues reported that chemical modification of one type of histone — called H2Av — leads to substantial changes in nucleosome shape.

However, cells with too short telomeres can lose capping function leading to a cellular catastrophe and genetic instability: the origin of many cancer types.

After identifying three different types of resistance to a promising investigational lung cancer drug in a phase 1 trial, a team of researchers led by Dana - Farber Cancer Institute scientists say new targeted inhibitors and combinations are urgently needed to stay ahead of tumors» constant and varied molecular shape - shicancer drug in a phase 1 trial, a team of researchers led by Dana - Farber Cancer Institute scientists say new targeted inhibitors and combinations are urgently needed to stay ahead of tumors» constant and varied molecular shape - shiCancer Institute scientists say new targeted inhibitors and combinations are urgently needed to stay ahead of tumors» constant and varied molecular shape - shifting.

We have also identified a decreased risk of ovarian cancer associated with all types of mutations predicted not to lead to NMD in BRCA2; the estimated risk was only significant for all mutations together and those mutations leading to in - frame splice site or frame shift mutations.

Beyond LFS, osteosarcoma is the most common type of bone cancer in all children, and after leukemia, the second leading cause of cancer death for them.

Professor Chien's research on how blood flow regulates interaction between the blood stream, blood cells and artery walls also leads to new information relevant to other types of cells, e.g., stem cells and cancer cells.

A research team, led by Chao Cheng, Ph.D., Assistant Professor in the Department of Genetics at The Geisel School of Medicine at Dartmouth, used gene expression data from breast cancer patients to computationally infer the presence of different types of immune cells.

The research ideas you develop at the workshop should: • Lead to the significant advancement of our understanding of sensor technologies suitable for liquid biopsy • Consider the practical challenges of low volume liquid usually taken for analysis and the inconsistency of sample preparation across point of care sites • Prioritise biomarkers with high specificity for cancer or even for multiple cancer types, including markers specific to cancers that will become aggressive as opposed to non-lethal disease

take a lead in developing the next generation of cancer cell lines and use cell lines to systematically explore in vitro sensitivity to large numbers of anticancer drugs and drug combinations in order to inform choice of cancer types for early drug trials.

Its scientists carry out research seeking new knowledge leading to the prevention of disease through vaccines and the treatment and cure of infectious diseases, cancer, inflammatory and autoimmune diseases such as rheumatoid arthritis, type 1 (juvenile) diabetes, Crohn's disease and asthma.

To help plug this diagnostic hole, Rebecca is leading the OCCAMS trial, a CRUK - funded multicentre study which is part of the International Cancer Genome Consortium (ICGC) global project to generate a comprehensive catalogue of genomic abnormalities in 50 tumour types.

The research, which appears in the EMBO Journal, indicates that when tissue responds to certain types of injury, mature cells seem to get younger and begin dividing rapidly, creating scenarios that can lead to cancer.

LA JOLLA — Scientists at the Salk Institute have uncovered a molecule whose mutation leads to the aggressive growth of a common and deadly type of lung cancer in humans.

Cancer Institute research highlights include innovative studies to develop individualized approaches for treatment and prevention of lung cancer; collaboration between medical and materials science researchers to develop treatments for various types of leukemia using nanotechnology to target only cancer cells; and development of novel therapeutics to treat metastatic melanoma using an approach that regulates the processes leading to tumor develoCancer Institute research highlights include innovative studies to develop individualized approaches for treatment and prevention of lung cancer; collaboration between medical and materials science researchers to develop treatments for various types of leukemia using nanotechnology to target only cancer cells; and development of novel therapeutics to treat metastatic melanoma using an approach that regulates the processes leading to tumor develocancer; collaboration between medical and materials science researchers to develop treatments for various types of leukemia using nanotechnology to target only cancer cells; and development of novel therapeutics to treat metastatic melanoma using an approach that regulates the processes leading to tumor develocancer cells; and development of novel therapeutics to treat metastatic melanoma using an approach that regulates the processes leading to tumor development.

The knowledge about how this cancer form arises and develops is still limited but new results from a research team led by Lene Uhrbom, Uppsala University / SciLifeLab, shows that disease progress and the malignancy are affected by the cell type from which the tumor originates as well as the age of the patient.

«HER2 - positive, ER - positive tumors have molecular features distinct from those of HER2 - positive, ER - negative cancers, suggesting that the two types of tumors should be treated with differently tailored approaches,» wrote study authors led by Luca Gianni, MD, of San Raffaele Scientific Institute in Milan.